Abstract:
:The possibility exists that agents used in anaesthesia may have adverse teratogenic effects on staff, patients, and developing fetuses. It has been shown that a range of neurotropic drugs, when injected into pregnant mice on the 9th day of gestation, produce a characteristic group of central nervous system malformations in their fetuses. We have studied the possible teratogenicity of pethidine, fentanyl, phenoperidine and lignocaine when tested in this way and conclude that they appear to have less effect than other neurotropic drugs previously tested.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Martin LV,Jurand Adoi
10.1111/j.1365-2044.1992.tb02267.xsubject
Has Abstractpub_date
1992-06-01 00:00:00pages
473-6issue
6eissn
0003-2409issn
1365-2044journal_volume
47pub_type
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