Abstract:
:Chronic granulomatous disease (CGD) is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an autosomal recessive form of chronic granulomatous disease. CGD has a variable natural history and age of presentation and should be considered when investigating a patient with recurrent or severe infections with catalase-positive organisms.
journal_name
Can Respir Jjournal_title
Canadian respiratory journalauthors
Rayment JH,Narang Idoi
10.1155/2016/4575942subject
Has Abstractpub_date
2016-01-01 00:00:00pages
4575942eissn
1198-2241issn
1916-7245journal_volume
2016pub_type
杂志文章abstract::Metastatic disease is one of the most common causes of calcified nodules in the lung or liver. The incidence of calcified metastasis mainly to the lung and liver is high at the initial presentation in patients with medullary thyroid carcinoma. Synchronous calcified metastasis in the lung and liver is reported for the ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2003/108081
更新日期:2003-01-01 00:00:00
abstract:Aim:In this study, we aimed to retrospectively investigate whether pectus excavatum (PE) is a risk factor for the development of primary spontaneous pneumothorax (PSP) and to determine its role in the etiology of the disease. Materials and Methods:Chest-computed tomography (CT) of the patients who were treated for spo...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2019/3291628
更新日期:2019-04-02 00:00:00
abstract::The bronchial epithelium has continuous contact with environmental agents initiating and maintaining airway type 2 inflammation in asthma. However, there is a lack of data on whether reduced airway eosinophilic inflammation can affect the production of epithelial-derived mediators, such as interleukin-25 (IL-25) and t...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2019/8607657
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Patients admitted to Lions Gate Hospital, North Vancouver, British Columbia, with a primary diagnosis of community-acquired pneumonia (CAP) have a mean length of stay (LOS) of 9.1 days compared with 7.9 days for peer group hospitals. This difference of 1.2 days results in an annual potential savings of 406 b...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2002/697424
更新日期:2002-07-01 00:00:00
abstract::Asthma is a common respiratory disease that can often be managed successfully. However, there are patients that do not respond to the maximum doses of standard therapy and subsequently have a reduced quality of life. Many factors can contribute to a failure to respond to treatment, and a comprehensive approach is impo...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2000/797306
更新日期:2000-09-01 00:00:00
abstract::Diffuse pulmonary ossification (DPO) is a rare form of interstitial lung disease. The present article describes a case of DPO in an elderly man who presented with progressive dyspnea on exertion and an isolated reduction in diffusing capacity for carbon monoxide. DPO may occur as sequelae of mitral stenosis, left hear...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2014/640419
更新日期:2014-01-01 00:00:00
abstract:Objective:To investigate the effects of Apatinib on the "stemness" of lung cancer cells in vivo and to explore its related mechanisms. Methods:A xenograft model of lung cancer cells A549 was established in nude mice and randomized into a control group (n = 4) and an Apatinib group (n = 4). Tumor tissues were harvested...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2020/2479369
更新日期:2020-08-10 00:00:00
abstract:OBJECTIVE:To achieve national consensus on standards of training, quality assurance and maintenance of competence for critical care ultrasound for intensivists and critical care trainees in Canada using recently published international training statements. DATA SOURCES:Existing internationally endorsed guidelines and ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2014/216591
更新日期:2014-11-01 00:00:00
abstract:Objectives:Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance. This study aimed to identify the underlying mechanism of in vivo development of clarithromycin resistance in M. absc...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2020/7623828
更新日期:2020-03-28 00:00:00
abstract:OBJECTIVES:The present study was designed to compare the performance of a new oxygen delivery device, the OxyArm (OA) (Southmedic Inc, Canada), with a standard nasal cannula (NC) (Salter-Style 1600, Salter Labs, USA) for both oxygen delivery and patient preference in patients on long-term oxygen therapy (LTOT). DESIGN...
journal_title:Canadian respiratory journal
pub_type: 杂志文章,随机对照试验
doi:10.1155/2006/729878
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Most children with asthma should be able to achieve acceptable control. However, are there differences between those with acceptable and poor control, and if so, how can health care approaches be modified accordingly? OBJECTIVE:To examine the characteristics of elementary school children aged five to 13 yea...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2006/149863
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Induced sputum cell counts are a noninvasive and reliable method for evaluating the presence, type and degree of airway inflammation in patients with asthma. Currently, standard nebulizer devices used for sputum induction in multiple patients are labelled as single-patient devices by the manufacturer, which ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2014/925305
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Although underused, written asthma action plans (AAPs) are associated with reduced numbers of emergency department (ED) visits and hospitalizations. OBJECTIVE:To describe the frequency of use and contents of any AAPs reported by patients presenting with exacerbations to three urban Canadian EDs. METHODS:Pr...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2014/498946
更新日期:2014-11-01 00:00:00
abstract::A case of intralobar pulmonary sequestration presenting with recurrent episodes of infection is reported. Pulmonary sequestration is a rare congenital malformation characterized by accessory lung tissue with no direct connection to the tracheobronchial tree and is supplied by an aberrant systemic artery. The aberrant ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2010/813106
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Asthma exacerbations can be provoked by many triggers such as allergens, respiratory irritants and viral infections. The relative importance of these has not been prospectively documented in a case-control study. OBJECTIVE:To assess the relative importance of colds and other nonclimatic historical triggers ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2000/812025
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Surgical resection for acute necrotizing lung infections is not widely accepted due to unclear indications and high risk. OBJECTIVE:To review results of resection in the setting of acute necrotizing lung infections. METHODS:A retrospective review of patients who underwent parenchymal resection between Janu...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2006/760390
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Asthma is the most common chronic disease in children. OBJECTIVES:To describe the prevalence of asthma and allergic disease in a multiethnic, population-based sample of Toronto (Ontario) school children attending grades 1 and 2. METHODS:In 2006, the Toronto Child Health Evaluation Questionnaire (T-CHEQ) us...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2010/913123
更新日期:2010-01-01 00:00:00
abstract::Diffuse panbronchiolitis (DPB) is a rare, chronic bronchiolar disease in non-Asian populations and is therefore commonly overlooked in Western countries. It usually affects nonsmokers and manifests as persistent air flow obstruction, chronic cough and interstitial nodular opacities. Untreated, the prognosis is poor. I...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2003/786531
更新日期:2003-11-01 00:00:00
abstract::Alpha-1 antitrypsin (A1AT) functions primarily to inhibit neutrophil elastase, and deficiency predisposes individuals to the development of chronic obstructive pulmonary disease (COPD). Severe A1AT deficiency occurs in one in 5000 to one in 5500 of the North American population. While the exact prevalence of A1AT defi...
journal_title:Canadian respiratory journal
pub_type: 杂志文章,实务指引
doi:10.1155/2012/920918
更新日期:2012-03-01 00:00:00
abstract::A 30-year-old female presented shortly after cadaveric renal transplantation with respiratory distress typical of a bacterial infection. Following initial improvement, she developed progressive respiratory failure, initially felt to be secondary to cytomegalovirus infection. Two bronchoalveolar lavages were nondiagnos...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2000/248915
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Intravenous epoprostenol, a prostaglandin analogue, has been a mainstay of therapy for patients with advanced pulmonary arterial hypertension (PAH) since the early 1990s. This medication has multiple side effects, and sudden discontinuation is potentially associated with severe sequelae. Several recent case ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章,评审
doi:10.1155/2011/104834
更新日期:2011-05-01 00:00:00
abstract:Objective:This epidemiological investigation aimed at determining the current situation regarding the diagnosis and treatment of chronic obstructive pulmonary disease (COPD), especially missed diagnosis and missed treatment, in a group of individuals residing in an island area of Ningbo. Methods:Adults ≥60 years of ag...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2019/6918340
更新日期:2019-08-01 00:00:00
abstract:Background:Adenoviruses are highly contagious pathogens which cause respiratory disease particularly in children; they may induce severe disease in infants. Human neutrophil peptides (HNPs) have been found to exhibit antiadenoviral activity. Thus, we have investigated HNPs in nasal aspirates (NAs) of children suffering...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2018/1038593
更新日期:2018-07-31 00:00:00
abstract:INTRODUCTION:The performance of blind closed pleural biopsy (BCPB) in the study of pleural exudates is controversial. OBJECTIVE:To assess the diagnostic yield of BCPB in clinical practice and its role in the study of pleural exudates. METHODS:Data were retrospectively collected on all patients who underwent BCPB perf...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2013/731352
更新日期:2013-09-01 00:00:00
abstract::Hantavirus cardiopulmonary syndrome (HCPS) is associated with rapid cardiopulmonary collapse from endothelial injury, resulting in massive capillary leak, shock and severe hypoxemic respiratory failure. To date, treatment remains supportive and includes mechanical ventilation, vasopressors and extracorporeal membrane ...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2006/359891
更新日期:2006-07-01 00:00:00
abstract:Background:Asthma and diabetes are both diseases that affect a wide range of people worldwide. As a common treatment for diabetes, metformin has also been reported to be effective in improving asthma outcomes. We conducted a combined analysis to examine the efficacy of metformin in reducing asthma exacerbation in patie...
journal_title:Canadian respiratory journal
pub_type: 杂志文章,评审
doi:10.1155/2020/9705604
更新日期:2020-08-04 00:00:00
abstract::A 40-year-old woman presented with profound weight loss, anemia and multiple pulmonary nodules. Further investigation revealed a hepatic abscess and a pelvic mass associated with an intrauterine device. Cultures of the hepatic abscess and from peripheral blood demonstrated Actinomyces species. The patient underwent an...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2005/461619
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Approximately 10% of patients hospitalized with community-acquired pneumonia (CAP) are bacteremic. Bacteremic Streptococcus pneumoniae pneumonia (BSPP) is the number one cause of mortality, representing up to 70% of all CAP deaths. In fact, all CAP guidelines have identified this issue as one of the most imp...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2004/461392
更新日期:2004-11-01 00:00:00
abstract::Alveolar soft-part sarcoma (ASPS) is a rare soft tissue tumour found in young adults that usually arises in skeletal muscle and occurs most frequently in the lower limbs. Radiological and pathological findings of ASPS in a 34-year-old man who presented with increasing shortness of breath over a period of four to six w...
journal_title:Canadian respiratory journal
pub_type: 杂志文章
doi:10.1155/2005/907856
更新日期:2005-10-01 00:00:00
abstract::The understanding of how inhaled allergens affect the asthmatic patient has changed significantly over the years. Allergen inhalation was first recognized as a cause of asthma in 1873, and the clinically important late asthmatic response (LAR) was demonstrated, albeit crudely, in 1952. Immunopathogenesis of the LAR wa...
journal_title:Canadian respiratory journal
pub_type: 杂志文章,评审
doi:
更新日期:1998-07-01 00:00:00