Abstract：
OBJECTIVE:Focal therapy (FT) is a tissuesparing treatment paradigm for localized prostate cancer (PCa) with the potential to improve functional outcomes while maintaining oncologic safety. This paper aims to provide an overview of important considerations and practical recommendations relating to the follow-up after FT. METHODS:Literature review of papers related to FT in PCa derived from Medline/Pubmed database. RESULTS:The recommended minimum follow-up period after FT is 5 years. Standard history taking should include: signs of disease progression, treatment-related complications and psychological aspects. Oncological outcome is based on serial prostate specific antigen monitoring, follow-up imaging (most commonly with multiparametric magnetic resonance imaging) and repeat biopsies (systematic from entire gland or targeted from treated zone). Significant PCa has been found at biopsy in up to 17% of patients after FT. Functional outcomes are evaluated using standardized questionnaires that relate to urinary function, erectile function and quality of life. A systematic review reports urinary continence in 83-100% of patients, erections sufficient for penetration in 54-100%. Outcomes differ between ablative energies and treatment templates. The most common side effects after FT are urinary retention (0-17%), urinary tract infection (UTI) (0-17%) and urinary stricture (0-5%). Rectal fistula is a rare complication occurring in up to 0.1-2% of patients. Clavien-Dindo Grade 3-4 complications are reported in 0-4% of patients. Type and rate vary with treatment modality. Complications should be reported using standardized reporting systems. Most data on FT outcomes come from small heterogeneous trials. Pooling of standardized data is necessary to advance the field of FT. CONCLUSION:Stringent follow-up after FT is required to confirm oncologic safety of the individual patient. Standardized data gathering and data pooling is necessary to evaluate whether FT can live up to its promise of improving functional outcomes while maintaining oncological safety.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Postema AW,Catellani M,Scheltema MJ,van den Bos W,de la Rosette JJsubject
Has Abstractpub_date
2016-07-01 00:00:00pages
364-74issue
6eissn
0004-0614issn
1576-8260journal_volume
69pub_type
杂志文章,评审abstract：:Most of the urodynamic studies are conducted in the laboratory during a brief recording time and under nonphysiological conditions and, thus, may fail to unfold the nature of existing pathological conditions of the lower urinary tract; false positives and false negatives are possible. To overcome some of the difficult...
journal_title：Archivos espanoles de urologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVES:Ultrasound guided biopsies are the mainstay in the diagnosis of prostate cancer. With the aim of improving diagnostic performances different protocols of prostate biopsy have been designed. The addition of vascular contrasts to the ultrasound allows for identification of hypervascular regions more likely to ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142006001000004
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:Renal cell carcinoma is constantly associated with calcification, but ossification is extremely scarce. METHOD: We retrospectively analyzed two cases with clear cell renal cell carcinoma with osseous metaplasia. RESULTS: We criticized the oldest case of woman whose a 32x31mm irregular renal mass with calcific...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVES:We review the main issues on epididymis obstruction and its diagnosis, as well as therapeutic indications and surgical techniques for epididymovasostomy. METHODS:We describe the microsurgical end-to-side epididymovasostomy technique using double needle 10-0 sutures. RESULTS:Various techniques of epididymov...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：:The presence of gas in the bladder wall and/or lumen (emphysematous cystitis) is an uncommon disease entity that may be caused by infectious organisms. Diabetes and chronic urinary infection are predisposing factors. Its clinical features are unspecific and the prognosis depends on the degree of aggressiveness at pres...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:We made a crystallographic analysis of 87 mixed-nucleus stones and found 4 groups of stones of this kind, which are as follow: urico-oxalic, oxalico-uric, phosphato-oxalic and oxalic-phosphatic. We did not find any mixed-nucleus, urico-phosphatic or phosphatico-uric stones and we explain this fact according to the kno...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1980-11-01 00:00:00
abstract：OBJECTIVE:To describe a new procedure for surgical correction of primary hypospadias with chordee. METHODS:The design of the urethral plate divide it in two flaps. Chordee must be resected in order to straighten the penis. Ventral side of neourethra is made with preputial skin or Mathieu procedure. This method has bee...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:To analyze the biochemical impact of treatment with phosphates in patients with recurrent calcium lithiasis and hypercalciuria. METHODS:20 patients were selected according to the following criteria: normal renal function, recurrent calcium nephrolithiasis, hypercalciuria, hypophosphatemia, normal calcium and...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：:We reviewed 19 patients presenting erectile deformities of the penis. Sixteen patients with congenital penile deviation were treated with the Nesbit procedure. All patients presented pronounced curvature of the penis and most of them were unable to achieve vaginal penetration. Five patients were submitted to original ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:Renal adenocarcinoma can present with a wide range of symptoms and clinical signs and among them pain is the more frequent. As a matter of fact, it can also assume the features of a reno-ureteral colic. This kind of symptom, however, is more frequently combined with macro-hematuria and seldom presents alone, even in t...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1990-09-01 00:00:00
abstract：:Although the laparoscopic ureteral reimplantation (LUR) has a history of over 20 years, its presence in the literature is relatively sparse, almost always in the form of small case series with low statistical power, which has prevented consistent results. It has proven to be a safe and effective technique, improving t...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the impact of a new renal lithiasis classification on the stone free rate. The new system would allow standarization of comparison between different series of percutaneous nephrolithotomy. MATERIAL AND METHODS:Patients undergoing NPCL between November 2011 and November 2016 were retrospectively a...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:To analyze surgery for renal cancer with venous thrombus at different levels, perioperative complications and prognostic factors associated to overall, cancer-specific and disease-free survival. MATERIAL AND METHODS:Retrospective analysis of 42 cases of renal cancer with venous thrombus performed between 20...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2017-07-01 00:00:00
abstract：:Six patients diagnosed as having urothelial carcinoma with varying degrees of squamous features are described. Four had pure squamous carcinoma. Two had transitional cell carcinoma (1 with squamous areas and the other had carcinoma in situ). The histological analyses of specimens were performed using immunohistochemic...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:We present our experience in 61 patients with partial or complete staghorn stone who underwent combined treatment with PCN and ESWL. We excluded the cases with an additional factor complicating staghorn stone, such as horseshoe kidney, severe ectopic, mal-rotated or high, with pyeloureteral junction stricture, etc. Th...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVE:We present two rare cases ofbladder xanthomata associated with transitional cell carcinoma. METHOD AND RESULTS:Cases description and selectionof related pictures. Review of the existing literature. CONCLUSIONS:Xanthomata are non-neoplastic lesionsconsisting of group of foamy lipidstoring histiocytes in thed...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To report on a patient who underwent surgery for renal carcinoma at the age of 12 years and who is alive and symptom-free after 22 years. METHODS:A 34-year-old female who underwent surgery for a right renal tumor when she was 12 is described. The histological analysis demonstrated renal adenocarcinoma. To da...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:The increase of isolation of beta-lactamase resistant Escherichia coli (BREC) strains makes treatment difficult. The objective of this study is to evaluate the situation in our environment. METHODS:Retrospective study including patients who presented positive urine cultures for E. coli in the Department of H...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2019-07-01 00:00:00
abstract：:The use of laser technology in the field of urologic surgery has experienced great advances over the past 20 years. Since the beginning of this century robotic technology has landed in a determined manner in our specially and every day will be more and more indications on what is going to have a final deployment. The ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000900028
更新日期：2008-11-01 00:00:00
abstract：:We describe a case of recurrent urinary tract infection in a male patient that had been repeatedly associated with sporadic sexual intercourse with his partner. The timing of the episodes and the bacteriological findings indicate this to be another uncommon case of urinary tract infection sexually transmitted by the f...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVES:To present one case of paratesticular leiomyosarcoma, a rare tumor which has been reported in 5 cases only in our country. To review the management of this type of tumor. METHODS:A 73-year-old male presenting with a 4 cm mass adjacent to the right testicle underwent excision of the mass, spermatic cord and ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-06-01 00:00:00
abstract：:Routine monitoring of PSA in patients with localized prostate cancer radically treated permits to identify those with biochemical recurrence only. Treatment options for biochemical failure include observation, surgery, radiotherapy alone or combined with hormonal therapy, brachytherapy, cryotherapy and hormone therapy...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Prostate cancer is a health problem in many Countries worldwide. Understanding the essential function of androgens in the prostate physiology led to the development of hormonal blockade as a therapeutic option in advanced disease, with limited response with time and development of resistance. In this stage, where cast...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:With the occasion of the Centenary of the Constitution in 1907 of the International Society of Urology, initially named Association, we point at the topics treated and analyze the presence of the Spanish urologists in the foundation act as well as their role and contributions in the meetings during the 20th ...
journal_title：Archivos espanoles de urologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:Various surgical procedures have been described for correction of stress urinary incontinence (SUI) which have afforded different results. Modifications to these procedures have been made in an attempt to reduce morbidity and the operating time without detriment to the efficacy of the procedures. Herein we describe tw...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:The research of the origin and development of the Medicalhyphen;surgical specialties in our environment has been, to my knowledge, limited. The aim of this work is to review it in reference to Urology, one of the first specialties developed in Mallorca during the second half of the XIX Century and the beginning of the...
journal_title：Archivos espanoles de urologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:To analyze the information provided by computed tomography (CT) in Fournier's gangrene, particularly in regard to the early diagnosis of the disease, and its utility as a complementary diagnostic imaging technique. METHODS:A retrospective study identified five cases of Fournier's gangrene. These patients had...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:We report the case of a 61-year-old male with the incidental diagnosis of intrathoracic renal ectopia during the workup study for a possible lung mass. METHODS:We performed a bibliographic review on the incidence, origin, clinical presentation and diagnosis of this type of renal ectopia. RESULTS:Chest x-ray...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000500011
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVES:The growing interest on increasing the number of biopsy samples during ultrasound guided prostatic biopsies moved us to evaluate the tolerability and complications of the extensive biopsy with/without blockage of neurovascular bundles. METHODS:A group of 222 patients underwent prostatic biopsy with the aim ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142005001000003
更新日期：2005-12-01 00:00:00
abstract：:The present study was undertaken to determine the reliability of CAT scanning in the preoperative evaluation to detect or discard pelvic lymph node involvement in patients with infiltrating bladder tumor. We compared the radiologic findings with the results of histopathologic examination of the lymph nodes following l...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
