Intermediate filament Nestin and the cell motility in cancer - a review. Retracted

Abstract:

:The intermediate filaments (Ifs) constitute the cytoskeleton which is a key feature of both prokaryotic and eukaryotic cells. The IFs are expressed throughout life and are involved in the regulation of cell differentiation, homeostasis, ageing and pathogenesis. The IFs not only provide structural integrity to the cell, but they are involved also in a range of cellular functions from organelle trafficking and cell migration to signaling transduction. The IFs are highly dynamic proteins, able to respond and adapt their network rapidly in response to intra- and extra-cellular cues. In cancer, these IFs play a crucial role with regard to cell invasion vial cell motility. The present review article will enlighten information about important IF nestin with regard to its role in cancer cell motility and invasion.

authors

Shi AM,Tao ZQ,Wang X,Wang YQ

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

2598-602

issue

12

eissn

1128-3602

issn

2284-0729

journal_volume

20

pub_type

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