Abstract:
INTRODUCTION AND HYPOTHESIS:The Patient Global Impression of Improvement (PGI-I) and International Consultation of Incontinence Questionnaire - Short Form (ICIQ-SF) are validated instruments for the assessment of patient reported outcome measures (PROM) following treatment of stress urinary incontinence (SUI). However, there is a paucity of evidence as to what represents a successful postintervention ICIQ-SF score. To determine the correlation between the postoperative ICIQ-SF scores with the PGI-I outcomes, the latter was considered one of the standard PROM following surgical treatment for SUI. The aim of this study was to determine, and if appropriate validate, an ICIQ-SF cut-off score that can predict a successful PROM as determined by PGI-I. METHODS:Four large datasets yielding 674 ICIQ-SF score/PGI-I outcome data pairs were used in this study for (a) determining and (b) validating the cut-off ICIQ-SF score for a successful PGI-I outcome. Two long-term follow-up datasets were used representing follow-up periods of 3 and 8 years of a randomized controlled trial (RCT) performed between April 2005 and April 2007 in a tertiary urogynaecology centre in Scotland, UK. All patients had urodynamic SUI or mixed urinary incontinence (MUI, with predominant SUI) and were randomized to treatment with either an inside-out or an outside-in transobturator tape (TVT-O or TOT, respectively) as a sole procedure. The datasets yielded 432 ICIQ-SF score/PGI-I outcome data pairs. Successful outcome was defined as "very much improved/much improved" on the PGI-I scale. SPSS v. 22.0 (IBM Corp., Armonk, NY) was used for all statistical analyses. The correlations and cut-off scores generated were then validated on two independent datasets representing the 1-year and 4-year follow-up periods of the multicentre RCT in six units in the UK. The datasets yielded 242 ICIQ-SF score/PGI-I outcome data pairs. All patients had urodynamic SUI or MUI (with predominant SUI) and were randomized to either adjustable single incision minisling (SIMS) or TVT-O. RESULTS:Significant correlations at the 0.01 level (two-tailed) were clearly demonstrated between ICIQ-SF scores at follow up and PGI-I outcomes in terms of success/failure in both the generation and validation datasets. Higher ICIQ-SF scores correlated with a 'poorer' PGI-I score. Using ROC analysis, a postoperative ICIQ-SF score of 6 was validated as approximately 90 % sensitive and 85 % specific for success/failure with a high Cohen's kappa coefficient of 0.83 (95 % CI 0.74 - 0.89). CONCLUSIONS:This two-stage study provided a robust well-validated postoperative ICIQ-SF cut-off score (of 6/21) that is likely to be associated with a patient-reported successful outcome on the PGI-I following surgical treatment with a midurethral sling in women at different stages of follow-up over 1 - 8 years. Such a cut-off score could enable the comparison of results between various studies and serve as a valuable guide for surgeons to counsel patients before and/or after surgical treatment. Our study fills a research gap in providing a way to compare trial results when baseline ICIQ-SF scores are not available.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Karmakar D,Mostafa A,Abdel-Fattah Mdoi
10.1007/s00192-016-3070-0subject
Has Abstractpub_date
2017-01-01 00:00:00pages
95-100issue
1eissn
0937-3462issn
1433-3023pii
10.1007/s00192-016-3070-0journal_volume
28pub_type
杂志文章abstract:INTRODUCTION AND HYPOTHESIS:Obstetric anal sphincter injury (OASIS) rates are reported to be higher in Asian women living in Western countries than in those living in Asia, but the reasons for the differences remain unclear. The objectives of this study were for a single examiner to prospectively compare OASIS rates in...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3649-8
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Ureteral injury during gynecological surgery can be managed in a variety of ways, from endoscopic stent placement to ureteroneocystotomy with accompanying psoas hitch and/or Boari flap. The majority of these occur during hysterectomy; therefore, gynecologic surgeons may not be as familiar wi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04627-4
更新日期:2021-01-06 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Several studies have indicated depression and anxiety to be associated with urinary incontinence (UI), however, the strength of the associations varies widely. The objective of this study was to determine these associations in a large survey. METHODS:In a cross-sectional population-based su...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1564-3
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Our aim was to assess whether differences in the ages of nulliparous women affect: (1) interobserver reliability, and (2) visualization of the levator ani (LA) muscle subdivisions in nulliparous women using 3D endovaginal ultrasound (3D-EVUS). METHODS:This was a cross-sectional study. Commu...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2053-7
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to evaluate hysterectomized and non-hysterectomized patients with prolapse and incontinence. Laparoscopic sacrohysteropexy (LSHP) and minimally invasive sacrocolpopexy (LMSCP) were done in combination with transobturator tape (TOT) and native tissue repair of the ant...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04519-7
更新日期:2020-09-08 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the incidence of de novo stress urinary incontinence (SUI) and sonographic features of implanted transvaginal mesh in continent women treated with Elevate(™) anterior/apical [single-incision mesh (SIM-A)] or Perigee(™) [transvaginal mesh with sacrospinous fixation (TVM + SS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2492-9
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:In July 2011, the US Food and Drug Administration (FDA) issued a safety communication regarding serious complications associated with surgical mesh for pelvic organ prolapse, prompting increased media and public attention. This study sought to analyze internet search activity and news article volume after ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3040-6
更新日期:2016-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Modern classifications of pelvic floor movements are based on pelvic floor assessment in a static midsagittal plane. This study presents a new and potentially useful 3D noninvasive tool for studying pelvic floor mobility in women with pelvic organ prolapse (POP). MATERIALS AND METHODS:Thirt...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-016-2948-1
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Obstetric fistula, caused by traumatic delivery and patient lack of access to obstetric care, is an important public health concern in developing countries, particularly in Sub-Saharan Africa. This research focuses on the experience of women living with obstetric fistula in Burkina Faso as w...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3235-x
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Rectocele is common in parous women but also seen in nulliparae. This study was designed to investigate the association between vaginal parity and descent of the rectal ampulla/rectocele depth as determined by translabial ultrasound (TLUS). METHODS:This retrospective observational study inv...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3552-8
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Intravesical onabotulinumtoxinA (Botox) injections are effective for the treatment of idiopathic overactive bladder (OAB) symptoms. The aim of our study was to assess the predisposing factors for urinary retention in women with OAB after intravesical Botox injection. METHODS:All participant...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3212-4
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The protocol and analysis methods for the Defining Mechanisms of Anterior Vaginal Wall Descent (DEMAND) study are presented. DEMAND was designed to identify mechanisms and contributors of prolapse recurrence after two transvaginal apical suspension procedures for uterovaginal prolapse. METH...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04511-1
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Robotic sacrocolpopexy is an effective and durable technique for pelvic organ prolapse repair. However, the learning curve for this procedure has underscored the need for an effective surgical training module. Given the cost, infection risk, poor tissue compliance, and scarcity of human cada...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03936-7
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Bladder pain syndrome is a difficult condition to treat. The purpose of this systematic review is to assess the effectiveness of various complementary therapies available for treatment. METHODS:This review was conducted in adherence with Preferred Reporting Items for Systematic Reviews. Cit...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-015-2886-3
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Depression is more common in patients with urinary incontinence (UI). Drug or rehabilitation therapy have been shown to be effective in reducing urgency UI (UUI) symptoms, but whether these treatments can ameliorate the negative impact of UUI on the psychological aspects of quality of life i...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-013-2116-9
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association (IUGA) Revised (PISQ-IR) measures sexual function in women with pelvic floor disorders (PFDs) yet is unwieldy, with six individual subscale scores for sexually active women and four for women who are not. ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3373-9
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare pelvic floor muscle strength (PFMS) and the prevalence of urinary incontinence (UI) and pelvic organ prolapse(POP) in women with and without diastasis recti abdominis (DRA) at 6-8 weeks postpartum. METHODS:Three hundred and ten women underwent routine ex...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04005-9
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to assess the efficacy of low-frequency electrotherapy (LFE) for female patients with early-stage detrusor underactivity (DUA) due to neuromuscular deficiency. METHODS:A total of 102 female patients were divided randomly into four groups: LFE-NC (normal compliance),...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-012-1714-2
更新日期:2012-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:A process of added qualification of transvaginal mesh (TVM) placement is desirable. METHODS:Through a physician-led partnership of specialty societies, centers of excellence, and industry, a core curriculum encompassing mesh/graft biology, technical skills, and safety can be coupled with cu...
journal_title:International urogynecology journal
pub_type: 共识发展会议,杂志文章
doi:10.1007/s00192-012-1679-1
更新日期:2012-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To estimate the risk of repeat surgery for recurrent prolapse or mesh removal after vaginal mesh versus native tissue repair for anterior vaginal wall prolapse. METHODS:We utilized longitudinal, adjudicated, healthcare claims from 2005 to 2010 to identify women ≥18 years who underwent an an...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2043-9
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To determine the clinical outcomes of adding a tension-releasing suture (TRS) appendage for manipulation of over-tensioned single-incision slings (SIS) as a means to relieve postoperative voiding dysfunction. METHODS:A retrospective observational study conducted from January 2010 to July 20...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3826-9
更新日期:2019-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:despite claims of equivalence to the tension-free vaginal tape, a variety of suburethral slings have been introduced, with various modifications. Complications in certain synthetic slings and meshes have led to a recent FDA public health notification. METHODS:we report the case histories an...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1244-8
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Rectovaginal fistula (RVF) is an abnormal epithelium-lined connection between the rectum and vagina. The primary effective treatment is surgical repair, but recurrence remains a challenge. Magnetic compression anastomosis (MCA), an alternative to suturing, has been developed to generate an a...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3097-2
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Identifying protective factors against pelvic floor disorders (PFDs) is important. We investigated whether cesarean delivery (CD) at the indication of abnormal second stage of labor (ASSL) has the same protective effect against future PFDs. METHODS:This population-based cohort study include...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04151-0
更新日期:2020-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Hysterectomy is often performed at the time of pelvic organ prolapse (POP) surgery; yet, there is insufficient evidence regarding the specific effect of hysterectomy on outcomes. We sought to determine the outcomes and associated short-term complications of mesh-based POP surgery with and wi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3244-9
更新日期:2017-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:No clear consensus exists on the selection of patients with pelvic organ prolapse (POP) for surgery. There is a need to preoperatively identify candidates who will benefit from surgery as there is no strict correlation between POP anatomical abnormalities and changes in symptoms and quality ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3423-3
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to investigate patient-reported goals after a tension-free vaginal tape operation for stress urinary incontinence and the correlation with postoperative incontinence. METHODS:A prospective study involving 70 women was carried out. Preoperatively, patients completed...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3049-x
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Preoperative urodynamic studies (UDS) are frequently performed before pelvic organ prolapse (POP) surgery to assess urethral and bladder function. The primary goal of this study is to examine how preoperative UDS are utilized and what value these studies have in patient treatment and/or coun...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-04084-8
更新日期:2020-08-01 00:00:00
abstract::Vaginal hysterectomy is the oldest and least invasive of the hysterectomy techniques and fulfills the evidence-based requirements as the preferred route of hysterectomy for benign gynecologic disease. Currently, vaginal hysterectomy is commonly utilized for treating uterine prolapse, but despite proven safety and effe...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2459-x
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to evaluate the long-term effect of thermoablative fractional CO2 laser (TACO2L) as an alternative treatment for early stages of stress urinary incontinence (SUI) in postmenopausal women with genitourinary syndrome of menopause. METHODS:A total of 161 postmenopausa...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3352-1
更新日期:2018-02-01 00:00:00