Abstract:
INTRODUCTION AND HYPOTHESIS:The aim of this study was to evaluate the long-term effect of thermoablative fractional CO2 laser (TACO2L) as an alternative treatment for early stages of stress urinary incontinence (SUI) in postmenopausal women with genitourinary syndrome of menopause. METHODS:A total of 161 postmenopausal patients (age 53.38 ± 5.1 years, range 45-65 years) with a clinical diagnosis of mild SUI were prospectively enrolled in the study. Patients received one treatment with TACO2L every 30-45 days, each treatment comprising four sessions, followed in all patients by a yearly treatment session at 12, 24 and 36 months. SUI was evaluated using the International Continence Society 1-h pad test and the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) before and after TACO2L treatment. RESULTS:TACO2L treatment was associated with a significant improvement in ICIQ-UI SF scores and 1-h pad weight test at 12 months (both p < 0.001), 24 months (both p < 0.001) and 36 months (both p < 0.001). Improvements were maintained for up to 36 months without the need for any further intervention. The results were confirmed by significant histological changes related to trophic restoration of the vagina, responsible for extrinsic and intrinsic mechanisms involved in urinary continence. CONCLUSIONS:Our results suggest that TACO2L is an efficient and safe novel treatment strategy in patients with mild SUI. Further investigation to confirm the long-term results presented here is still warranted.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
González Isaza P,Jaguszewska K,Cardona JL,Lukaszuk Mdoi
10.1007/s00192-017-3352-1subject
Has Abstractpub_date
2018-02-01 00:00:00pages
211-215issue
2eissn
0937-3462issn
1433-3023pii
10.1007/s00192-017-3352-1journal_volume
29pub_type
杂志文章abstract::A damaged sphincteric unit or support system, unstable urethral deformability or damaged sensory innervation are all potential causes of a dysfunctional urethral sphincter. With the current improvement in pharmacological targets and urodynamic understanding, studies have begun quantifying individual structures and the...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-019-04104-7
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To examine urinary retention (UR) after female urethral sling placement in patients with or without detrusor underactivity (DU) or Valsalva voiding whose urodynamics (UDS) accurately reproduced voiding symptoms to determine whether the reproduction of voiding symptoms on UDS in those with DU...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04623-8
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim was to review the impact of pelvic organ prolapse surgery on sexual function. METHODS:Every 4 years and as part of the Fifth International Collaboration on Incontinence we reviewed the English-language scientific literature after searching PubMed, Medline, Cochrane library and Cochr...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-013-2176-x
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The purpose of this study is to determine the effect of silver coating of polypropylene implants on infection in hernia surgery. METHODS:Silver-coated and non-silver-coated large pore monofilament polypropylene mesh implants were compared with and without infection (four groups). The implan...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1330-y
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The goal of the study was to define the time needed to obtain maximal organ descent and hiatal distension during Valsalva measured by transperineal ultrasound. Secondarily, we aimed to describe the timing of these events in relationship to each other. METHODS:We undertook a retrospective re...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1533-x
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Several studies have indicated depression and anxiety to be associated with urinary incontinence (UI), however, the strength of the associations varies widely. The objective of this study was to determine these associations in a large survey. METHODS:In a cross-sectional population-based su...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1564-3
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We report 2-year data on the effectiveness and safety of the MiniArc single-incision sling in women with stress urinary incontinence. METHODS:This multi-center, prospective, single-arm, industry-sponsored study measured the effectiveness of the MiniArc sling via quantitative (cough stress t...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00192-012-1734-y
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Vaginal pessaries may offer symptomatic improvement for women with pelvic organ prolapse (POP) or urinary incontinence (UI). This study aimed to investigate multidisciplinary perspectives on vaginal pessary use in clinical practice and to understand the service organisation of vaginal pessar...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1985-7
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Different forms of urinary drainage are applied after anterior colporrhaphy. Suprapubic urinary catheter (SUC) and indwelling urinary catheter (IUC) for 2 to 96 h are preferred. If there is no difference in symptomatic urinary tract infection (SUTI) or complications between IUCs for 96 and 2...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-010-1221-2
更新日期:2010-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Determine if women with fibromyalgia report increased bother from pelvic organ prolapse compared with women without fibromyalgia. METHODS:We performed a cross-sectional study of women with symptomatic prolapse on consultation with a private urogynecology practice within a 46-month period. A...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2280-y
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective of the present study was to adapt the CONTILIFE, a quality-of-life questionnaire, into Turkish and to reveal its psychometric properties in women suffering from stress urinary incontinence (SUI). METHODS:Ninety-eight patients with a symptom of SUI participated in the study and...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3823-z
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to identify risk factors for postpartum anatomic pelvic organ prolapse (aPOP) by comparing women with and without aPOP at 6 weeks postpartum with regard to pelvic floor measurements antepartum and obstetrical characteristics. METHODS:We carried out a prospective observatio...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3650-2
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:There are few direct comparisons between the first-generation trocar-guided and the second-generation single-incision mesh systems in the treatment of anterior pelvic organ prolapse (POP). Hence, the purpose of this retrospective review was to compare 18-month operative success in female pat...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2772-z
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Vaginal bulging is considered the key symptom for genital organ prolapse. The aim was to investigate the age-related prevalence and frequency of symptomatic pelvic organ prolapse (sPOP) and other pelvic floor symptoms in nonpregnant nullipara aged 25-64 years. METHODS:This national postal a...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3684-5
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Delays in receiving obstetric care during labor contribute to high rates of maternal morbidity in sub-Saharan Africa. This exploratory study was conducted to identify important delays experienced during the development and subsequent repair of obstetric fistula in northern Tanzania. METHODS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3416-2
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the incidence of de novo stress urinary incontinence (SUI) and sonographic features of implanted transvaginal mesh in continent women treated with Elevate(™) anterior/apical [single-incision mesh (SIM-A)] or Perigee(™) [transvaginal mesh with sacrospinous fixation (TVM + SS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2492-9
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to report patterns of sling and transvaginal mesh-related complications using the IUGA/ICS classification of prosthesis-related complications. METHODS:This was a retrospective chart review of all patients who underwent surgical removal of sling, transvaginal mesh, and sacr...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究
doi:10.1007/s00192-015-2913-4
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We evaluated whether vaginal tampon training (VTT) combined with pelvic floor muscle training (PFMT) results in better outcomes than PFMT alone for treating stress urinary incontinence (SUI). METHODS:This was a randomized, controlled study. Patients were allocated to either the combined pro...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-018-3585-7
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We aimed to determine the rate of readmission and reoperation for patients undergoing midurethral sling (MUS) placement for stress urinary incontinence (SUI). METHODS:The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was queried to identify all ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3551-9
更新日期:2018-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Avulsion of the puborectalis muscle from its bony insertion is common in women presenting with prolapse. We present a simple vaginal technique for levator reconstruction. METHODS:This is a prospective surgical pilot study comprising 17 patients enrolled to undergo levator repair in the cont...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1984-8
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Laparoscopic sacral colpoperineopexy (LSCP) involves posterior graft extension to the perineum for improved posterior support. The objective of this study was to determine whether posterior measurements differed between those that had graft extension done abdominally (A-LSCP) or abdomino-vag...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1302-2
更新日期:2011-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Robotic sacrocolpopexy is an effective and durable technique for pelvic organ prolapse repair. However, the learning curve for this procedure has underscored the need for an effective surgical training module. Given the cost, infection risk, poor tissue compliance, and scarcity of human cada...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03936-7
更新日期:2019-08-01 00:00:00
abstract::Leiomyomas of the external genitalia are uncommon soft tissue tumors. We report the case of a 47-year-old woman with perineal leiomyomas mimicking Bartholin's gland mass according to the preoperative magnetic resonance imaging (MRI) findings. Leiomyomas in the vulvar region should be differentiated from complicated Ba...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-0998-3
更新日期:2010-04-01 00:00:00
abstract::Aggressive angiomyxoma is a rare soft tissue tumor of the pelvis. Notorious for its locally infiltrative behavior, this tumor is identified by pathological appearance. Grossly gelatinous, spindle cells widely separated by collagen fibrils with vascular components can be microscopically visualized. Wide local excision ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1867-z
更新日期:2013-05-01 00:00:00
abstract::The concept of genitourinary syndrome of menopause (GSM) was recently introduced and has been gaining widespread use. While some justifications for its introduction are straightforward, others may be questionable. Numerous unspecific symptoms and signs were included in the definition of the syndrome, but the minimum n...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-017-3295-6
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to compare medium-term efficacy and safety of a partially absorbable mesh kit and native tissue repair in pelvic organ prolapse (POP). MATERIALS AND METHODS:Women with primary POP stage ≥ II were randomized to transvaginal trocar-guided partially absorbable mesh (81 women)...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00192-018-3757-5
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Stress urinary incontinence (SUI) may appear after the correction of pelvic organ prolapse (POP). The aim of this study was to externally validate a described predictive model for de novo SUI and to assess its clinical performance when used as a diagnostic test. METHODS:This was a retrospec...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3805-1
更新日期:2019-10-01 00:00:00
abstract::Recurrent pelvic organ prolapse occurs rarely after obliterative procedures. The optimal surgical approach for therapy is unknown. We describe a case of recurrent prolapse after LeFort colpocleisis. The patient presented with stage III prolapse through the lateral vaginal channel. At surgery, the prolapse was repaired...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1541-x
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:Recurrent urethral diverticulum has been reported in 23% of cases after primary repair and can be difficult to manage. The aim of this video is to demonstrate a surgical technique of repairing a recurrent diverticulum in a woman who had two previous procedures, one with a Martius labial fat pad graft. MET...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04357-7
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to assess the efficacy of intravesical hyaluronic acid (HA) and chondroitin sulfate (CS), alone or in combination, for recurrent urinary tract infections (RUTIs) in adult female patients using a systematic review and meta-analysis. METHODS:English-language articles were ob...
journal_title:International urogynecology journal
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00192-017-3508-z
更新日期:2018-07-01 00:00:00