Abstract:
INTRODUCTION AND HYPOTHESIS:The objective was to assess the efficacy of intravesical hyaluronic acid (HA) and chondroitin sulfate (CS), alone or in combination, for recurrent urinary tract infections (RUTIs) in adult female patients using a systematic review and meta-analysis. METHODS:English-language articles were obtained from the MEDLINE, Embase, and Cochrane databases through November 2016, by manual searching and cross-referencing. Randomized and nonrandomized trials of adult female patients with a documented history of RUTIs who received HA, CS or HA plus CS were included. The random effects model was applied to all pooled analyses. Risk of bias was assessed for individual studies and across studies. RESULTS:Two randomized (n = 85) and six nonrandomized (n = 715) studies met the inclusion criteria. These studies assessed HA ± CS; studies of CS alone were not identified in the search. HA ± CS decreased the UTI rate per patient-year (pooled mean difference [MD] -2.56; 95% confidence interval [CI] -3.86, -1.26; p < 0.001) and increased the time to first UTI recurrence (pooled MD 130.05 days; 95% CI 5.84, 254.26; p = 0.04). There was heterogeneity in most outcomes considered, and publication bias in many studies. The standard of trial reporting was low. The patient population size, and the number of studies included, were small. CONCLUSIONS:HA ± CS appears to reduce the rate of UTI and increase the time to recurrence in women with RUTI. As randomized controlled studies are available only for HA plus CS, the quality of evidence is higher for the combination than for HA alone.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Goddard JC,Janssen DAWdoi
10.1007/s00192-017-3508-zsubject
Has Abstractpub_date
2018-07-01 00:00:00pages
933-942issue
7eissn
0937-3462issn
1433-3023pii
10.1007/s00192-017-3508-zjournal_volume
29pub_type
杂志文章,meta分析,评审abstract:OBJECTIVE:The aim of this study was to assess the incidence of de novo stress urinary incontinence (SUI) and sonographic features of implanted transvaginal mesh in continent women treated with Elevate(™) anterior/apical [single-incision mesh (SIM-A)] or Perigee(™) [transvaginal mesh with sacrospinous fixation (TVM + SS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2492-9
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association (IUGA) Revised (PISQ-IR) measures sexual function in women with pelvic floor disorders (PFDs) yet is unwieldy, with six individual subscale scores for sexually active women and four for women who are not. ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3373-9
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Jorge and Wexner devised a questionnaire for anal incontinence (AI), known as the Wexner scale (WS). Specific validated questionnaires are essential for the assessment of symptom severity. The objective was to accomplish the cultural adaptation and validation of the Portuguese version of the...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2927-y
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Many adult women have resident urinary bacteria (urinary microbiome/microbiota). In adult women affected by urinary urgency incontinence (UUI), the etiologic and/or therapeutic role of the urinary microbiome/microbiota remains unknown. We hypothesized that microbiome/microbiota characteristi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2847-x
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Mediolateral episiotomy is one of the most frequent surgical interventions performed in obstetrics. There is conflicting evidence as to whether mediolateral episiotomy reduces the risk of obstetric anal sphincter injuries (OASI). Recent studies suggest that functional asymmetry of pelvic flo...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3560-3
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Our aim was to validate the Brazilian Portuguese version of the International Federation of Gynecology and Obstetrics (FIGO) Assessment Scoring System (FASS) to identify and quantify signs and symptoms related to pelvic floor dysfunction. METHODS:One hundred and seventy-nine women aged 18-8...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3789-x
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:A 10-year retrospective study was done to determine the outcome of vaginal repair for supratrigonal vesicovaginal fistulae (VVF). METHODS:One hundred thirty-two urinary fistulae were managed from 2001 to 2011 which include 34 ureterovaginal and 98 lower urinary tract fistulae. Fifty-three o...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1665-7
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:To identify risk factors associated with lower urinary tract injury at the time of performing hysterectomy for benign indications. METHODS:We conducted a multi-center case-control study of women undergoing hysterectomy for benign disease. Cases were identified via ICD-9 codes for lower urinary tract injury ...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究
doi:10.1007/s00192-013-2308-3
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We aimed to determine the prevalence of urinary incontinence (UI) in nulliparous female university students and to provide an overview of risk factors associated with urinary continence. METHODS:A total of 1,397 female university students aged 18-28 years were enrolled into this cross-secti...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04360-y
更新日期:2021-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To estimate the incidence rates of stress urinary incontinence (SUI) surgery among Finnish women from 1987 to 2009 by age, and to evaluate the trends in SUI surgery. METHODS:We conducted a retrospective register-based study. All SUI procedures on adult women over age 18 years in Finland wer...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2926-z
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The prevalence of levator avulsion after vaginal delivery ranges from 10 to 30 %. To our knowledge, no previous studies have used anorectal manometry (AM) to assess this injury's impact on the functionality of the anal sphincter complex. We hypothesized that women with levator avulsion have ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2623-3
更新日期:2015-07-01 00:00:00
abstract::In July of 2011 the U.S. Food and Drug Administration (FDA) released a safety communication entitled "UPDATE on Serious Complications Associated with Transvaginal Placement of Surgical Mesh for Pelvic Organ Prolapse." The stated purpose of this communication is to inform health care providers and patients that serious...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1581-2
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to evaluate the predictors and reasons for help-seeking behavior among women with urinary incontinence (UI) in Germany and Denmark. METHODS:This international postal survey was conducted in 2014. In each country, 4,000 women of at least 18 years of age were randomly...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3434-0
更新日期:2018-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Laparoscopic sacral colpoperineopexy (LSCP) involves posterior graft extension to the perineum for improved posterior support. The objective of this study was to determine whether posterior measurements differed between those that had graft extension done abdominally (A-LSCP) or abdomino-vag...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-010-1302-2
更新日期:2011-04-01 00:00:00
abstract::Genitourinary syndrome of menopause (GSM) is common among postmenopausal women, but, in general, not all of the patients seek medical advice as this sensitive issue can cause them embarrassment. OBJECTIVES:To explore the prevalence of GSM among Thai postmenopausal women and their disclosure of and attitude towards GS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03991-0
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:InTone(TM) (InControl Medical) is a nonimplanted vaginal device providing biofeedback and electrical stimulation of pelvic floor muscles. The purpose of this study was to assess its efficacy and usability for treating urinary incontinence (UI). METHODS:Women with UI (stress, urge, mixed) were recruited fo...
journal_title:International urogynecology journal
pub_type: 临床试验,杂志文章
doi:10.1007/s00192-014-2476-9
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The purpose of this study was to apply a human factors research approach to identify flow disruptions, deviations in the optimal course of care, in robotic abdominal sacrocolpopexy procedures with the ultimate goal of developing system interventions to improve the safety and efficiency of ro...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03929-6
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Previous studies have included a limited number of randomized controlled trials (RCTs) and compared limited parameters after treatment with imidafenacin and other anticholinergic drugs (ADs) for overactive bladder syndrome (OAB), and controversy about the superiority of these ADs still remains. We aim to update...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-020-04329-x
更新日期:2020-05-14 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS:A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS:Out of 2,316, eight studies w...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-017-3272-0
更新日期:2017-09-01 00:00:00
abstract::A pubic cartilaginous cyst is a rare condition and is considered a result of degenerative changes in the symphysis pubis, mainly described in elderly multiparous women. There are only a few reported cases in the literature, and patients presented most frequently with a painful vaginal/vulvar mass. This case report is ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-014-2523-6
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We evaluated whether vaginal tampon training (VTT) combined with pelvic floor muscle training (PFMT) results in better outcomes than PFMT alone for treating stress urinary incontinence (SUI). METHODS:This was a randomized, controlled study. Patients were allocated to either the combined pro...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-018-3585-7
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION:Recurrent urethral diverticulum has been reported in 23% of cases after primary repair and can be difficult to manage. The aim of this video is to demonstrate a surgical technique of repairing a recurrent diverticulum in a woman who had two previous procedures, one with a Martius labial fat pad graft. MET...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04357-7
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:At our institution many symptomatic patients must wait months or years for surgery. Our aim was to determine the rates of clinically significant pelvic organ prolapse (POP) progression and identify risk factors associated with POP progression. METHODS:Data from a prospectively maintained da...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3450-0
更新日期:2018-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Urinary incontinence (UI) is common among the elderly, but the literature is sparse on the surgical treatment of UI among the elderly. This systematic review aims to assess the effectiveness of surgical interventions as treatment for urinary incontinence in the elderly population ≥65 years o...
journal_title:International urogynecology journal
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00192-014-2573-9
更新日期:2015-08-01 00:00:00
abstract::Pelvic reconstructive surgeons have suspected for over a century that childbirth-related trauma plays a major role in the aetiology of female pelvic organ prolapse. Modern imaging has recently allowed us to define and reliably diagnose some of this trauma. As a result, imaging is becoming increasingly important, since...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-011-1459-3
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Avulsion of the puborectalis muscle from its bony insertion is common in women presenting with prolapse. We present a simple vaginal technique for levator reconstruction. METHODS:This is a prospective surgical pilot study comprising 17 patients enrolled to undergo levator repair in the cont...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1984-8
更新日期:2013-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:World Health Organisation (WHO) data suggest that more than two million women and girls live with fistula and that an additional 50-100,000 are newly affected each year. In Tanzania, it has been estimated that there are between 1,200 and 3,000 new cases of obstetric fistula annually. METHOD...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2185-9
更新日期:2014-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to compare vaginal and clitoral sensory thresholds in women with pelvic organ prolapse and women with normal pelvic anatomy. METHODS:Quantitative sensory thresholds for warm, cold, and vibratory sensations were measured at the vagina and clitoral area of women with pelvic ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2637-5
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The literature presents controversial results regarding the role of delivery mode in pelvic floor muscle (PFM) function after birth. Some studies showed a greater impairment of PFM function after vaginal delivery compared with cesarean section, while others have not identified a significant ...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-020-04231-6
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Presence of microbial communities (microbiota) in an organ system depends on environmental factors, such as oxygen availability. We describe a novel technique to measure bladder urine oxygen tension (BUOT) in ambulatory women and use that technique to compare BUOT values to female urinary mi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03931-y
更新日期:2019-08-01 00:00:00