Animal Models for Tuberculosis in Translational and Precision Medicine.

Abstract:

:Tuberculosis (TB) is a health threat to the global population. Anti-TB drugs and vaccines are key approaches for TB prevention and control. TB animal models are basic tools for developing biomarkers of diagnosis, drugs for therapy, vaccines for prevention and researching pathogenic mechanisms for identification of targets; thus, they serve as the cornerstone of comparative medicine, translational medicine, and precision medicine. In this review, we discuss the current use of TB animal models and their problems, as well as offering perspectives on the future of these models.

journal_name

Front Microbiol

authors

Zhan L,Tang J,Sun M,Qin C

doi

10.3389/fmicb.2017.00717

subject

Has Abstract

pub_date

2017-05-04 00:00:00

pages

717

issn

1664-302X

journal_volume

8

pub_type

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