Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients.

Abstract:

BACKGROUND:The association between hypoalbuminaemia and a new diagnosis of cancer is as yet unknown. OBJECTIVE:This study aimed to assess whether unexplained hypoalbuminaemia was associated with an increased risk of subsequent new cancer diagnosis within the next 12 months. METHODS:A cohort study was performed using a large UK database of adult primary care patients. Patients with a serum albumin test, either low or normal, were followed for 12 months for a new diagnosis of non-skin cancer. Logistic regression was used to assess for relationships between hypoalbuminaemia and cancer diagnoses. RESULTS:A total of 100 122 participants had at least one albumin test result. Of these, 5753 (5.75%) had a result <35g/l, of whom 1634 developed cancer within 12 months. Of the 94 116 patients with normal albumin values, 13 906 developed cancer. Hypoalbuminaemia was associated with an increased risk of subsequent cancer diagnosis within 12 months (odds ratio [OR]: 2.29; 95% confidence interval [CI]: 2.15-2.43). This association was smaller in magnitude after controlling for other conditions known to affect albumin levels (OR: 1.29; 95% CI: 1.12-1.49). CONCLUSIONS:Low albumin levels were associated with an increased risk of cancer. This finding needs to be confirmed in other primary care populations.

journal_name

Fam Pract

journal_title

Family practice

authors

Merriel SW,Carroll R,Hamilton F,Hamilton W

doi

10.1093/fampra/cmw051

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

449-52

issue

5

eissn

0263-2136

issn

1460-2229

pii

cmw051

journal_volume

33

pub_type

杂志文章
  • Non-steroids anti-inflammatory drugs and risk of peritonsillar abscess in pharyngitis: a French longitudinal study in primary care†.

    abstract:BACKGROUND:The safety of non-steroids anti-inflammatory drugs (NSAIDs) in the context of pharyngitis is doubtful with contradictory results in the literature. OBJECTIVE:To evaluate the risk of peritonsillar abscess (PTA) associated to NSAIDs consumption during a pharyngitis episode observed in primary care. METHOD:A ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmy111

    authors: Piroulas C,Devillers L,Souty C,Sicsic J,Boisnault P,François M

    更新日期:2019-07-31 00:00:00

  • Patient characteristics which are related to the doctor-patient interaction.

    abstract::Audiotapes were made of 140 visits to the offices of family physicians by patients with acute or chronic problems. The tapes were analysed using Bales Interaction Process Analysis to identify interviews which were patient-centred: interviews in which the physician was supportive and encouraged the patient to express h...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/1.1.30

    authors: Stewart M

    更新日期:1984-03-01 00:00:00

  • Tympanometry for diagnosis and treatment of otitis media in general practice.

    abstract:OBJECTIVE:The aim of this study was to evaluate the role of tympanometry for diagnosis, treatment and follow-up of otitis media in general practice. METHODS:The results from otoscopy performed by 40 physicians in general practice in Vejle County, Denmark were combined with the clinical condition and this was recorded ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/17.4.317

    authors: Johansen EC,Lildholdt T,Damsbo N,Eriksen EW

    更新日期:2000-08-01 00:00:00

  • Disability and quality of life in heart failure patients: a cross-sectional study.

    abstract:BACKGROUND:Although both hospitalization and mortality due to heart failure (HF) have been widely studied, less is known about the impact of HF on disability and quality of life. AIM:To assess the degree of disability and quality of life in HF patients attended at family medicine centres. DESIGN AND SETTING:Cross-sec...

    journal_title:Family practice

    pub_type: 杂志文章,多中心研究

    doi:10.1093/fampra/cmz017

    authors: García-Olmos L,Batlle M,Aguilar R,Porro C,Carmona M,Alberquilla A,Sánchez-Gómez LM,Monge E,López-Rodríguez AB,Benito L,Baños N,Simón A,Martínez-Álvarez MA,Luque EM,García-Benito C

    更新日期:2019-11-18 00:00:00

  • Physician and practice characteristics associated with immunoglobulin test ordering.

    abstract:Background:Primary care test requests for serum immunoglobulins are rising rapidly, with concerns that many requests may be unnecessary. Evidence suggests some characteristics of general practitioners (GPs) and practices are associated with higher test ordering. Objective:To identify the physician and practice charact...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmx063

    authors: Cadogan SL,Browne JP,Bradley CP,Fitzgerald AP,Cahill MR

    更新日期:2018-01-16 00:00:00

  • Patient education by a family nurse as a model for training residents.

    abstract::There is need for a practical model of patient education in the primary care setting that can also be used as a method for teaching primary care residents about patient education. This project modified a previously established and well-defined role for a family nurse in order to provide such a patient care-based learn...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/6.2.114

    authors: Solberg LI,Nesvacil LJ,Stoller JE

    更新日期:1989-06-01 00:00:00

  • Focus on early-career GPs: qualitative evaluation of a multi-faceted educational intervention to improve antibiotic prescribing.

    abstract:Background:We conducted an educational intervention emphasizing rational antibiotic prescribing in early-career General Practitioners (GP) in vocational training (trainees). The intervention consisted of an online introduction module, an online communication training module, face-to-face workshops, and cases to be disc...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmx074

    authors: Deckx L,Anthierens S,Magin PJ,Morgan S,McArthur L,Yardley L,Dallas A,Little P,van Driel ML

    更新日期:2018-01-16 00:00:00

  • Antibiotic use in upper respiratory tract infections in New Zealand.

    abstract::Upper respiratory tract infections (URTIs) are a common reason for presentation to general practitioners. The current study used computerised consultation records of 100,222 patients from 17 general practices in New Zealand for the 12-month period 1 July 1991-30 June 1992. URTIs were noted in 8.9% of all consultations...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/12.2.166

    authors: McGregor A,Dovey S,Tilyard M

    更新日期:1995-06-01 00:00:00

  • How science thinks and practice acts: bridging the gap in weight management interventions for adolescents.

    abstract:BACKGROUND:Adolescent obesity calls for evidence-based treatment approaches given its long-term physical and psychosocial consequences. However, research shows there are many problems in the translation of scientific evidence into practice. OBJECTIVE:The aim of this study was to develop science- and practice-based rec...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/cmr086

    authors: Swan E,Bouwman L,de Roos N,Koelen M

    更新日期:2012-04-01 00:00:00

  • Screening of depression in patients with chronic medical diseases in a primary care setting.

    abstract:BACKGROUND:Patients with chronic medical diseases may have depression that is not recognized by their primary care physicians. OBJECTIVES:We aimed to examine the application of Zung's Self-Rating Depression Scale (SDS) in the screening of depression in primary care patients with chronic medical diseases in a Chinese p...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/15.1.67

    authors: Leung KK,Lue BH,Lee MB,Tang LY

    更新日期:1998-02-01 00:00:00

  • Potential barriers to the use of health services among ethnic minorities: a review.

    abstract:BACKGROUND:Ethnic minority patients seem to be confronted with barriers when using health services. Yet, care providers are often oblivious to these barriers, although they may share to some extent the burden of responsibility for them. In order to enlighten care providers, as to the potential pitfalls that may exist, ...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/cmi113

    authors: Scheppers E,van Dongen E,Dekker J,Geertzen J,Dekker J

    更新日期:2006-06-01 00:00:00

  • A cross-sectional study of United States family medicine residency programme director burnout: implications for mitigation efforts and future research.

    abstract:BACKGROUND:Academic physician burnout is concerning. Too little is known about factors associated with residency programme director burnout. Continued uncertainty risks adverse outcomes including graduate medical education leadership turnover and negative impact on recruiting and retaining under-represented minority re...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmaa075

    authors: Psenka TM,Freedy JR,Mims LD,DeCastro AO,Berini CR,Diaz VA,Jarrett JB,Steyer TE

    更新日期:2020-11-28 00:00:00

  • Do clinical findings in lower respiratory tract infection help general practitioners prescribe antibiotics appropriately? An observational cohort study in general practice.

    abstract:BACKGROUND:Antibiotics are over-prescribed for lower respiratory tract infection (LRTI). The influence of clinicians' history and examination findings on antibiotic prescribing for LRTI has not been directly assessed, and the extent to which these clinical findings predict appropriate antibiotic prescribing is unknown....

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmi100

    authors: Hopstaken RM,Butler CC,Muris JW,Knottnerus JA,Kester AD,Rinkens PE,Dinant GJ

    更新日期:2006-04-01 00:00:00

  • A survey of Dutch GPs' attitudes towards help seeking and follow-up care for relatives bereaved by suicide.

    abstract:BACKGROUND:Relatives who are bereaved by suicide likely consult their GP when they feel the need for professional help. GPs may play a key role in establishing who is at risk for adverse consequences of the loss as they are familiar with relatives' possible psychiatric vulnerabilities. The availability of evidence-base...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmp046

    authors: de Groot M,van der Meer K,Burger H

    更新日期:2009-10-01 00:00:00

  • Characteristics and perceptions of after-hours callers.

    abstract::After-hours care remains an important aspect of community practice although little is known about the views of either physicians or patients. This study presents an analysis of 12 499 after-hours calls made to a family practice centre over a five-year period, and 798 follow-up telephone interviews conducted with peopl...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/2.1.10

    authors: Evens S,Curtis P,Talbot A,Baer C,Smart A

    更新日期:1985-03-01 00:00:00

  • Welfare rights advice in primary care: prevalence, processes and specialist provision.

    abstract:BACKGROUND:Despite persistent poverty-related health inequalities, few sustained responses have been developed in primary care. Welfare rights provision has been proposed as one potential pathway to addressing health inequalities. OBJECTIVES:This study was set up to address the prevalence of welfare rights issues in g...

    journal_title:Family practice

    pub_type: 杂志文章,多中心研究

    doi:10.1093/fampra/20.1.48

    authors: Harding R,Sherr L,Sherr A,Moorhead R,Singh S

    更新日期:2003-02-01 00:00:00

  • Qualitative research and the problem of judgement: lessons from interviewing fellow professionals.

    abstract:BACKGROUND:Qualitative research methods are recognized increasingly as valuable tools for primary care research, and add an extra dimension to quantitative work. OBJECTIVE:The aim of this study was to illustrate the benefits and problems attending the dual role of clinician/qualitative researcher. METHODS:As part of ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/19.3.285

    authors: Chew-Graham CA,May CR,Perry MS

    更新日期:2002-06-01 00:00:00

  • Selections from current literature: hormone therapy in postmenopausal women.

    abstract::The articles reviewed for this issue of 'Selections' concern potential therapies to prevent osteoporosis and cardiovascular disease in postmenopausal women. Each therapy is controversial and provokes more questions than answers. The most benign intervention is the administration of calcium to postmenopausal women whos...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/8.3.288

    authors: Froom J

    更新日期:1991-09-01 00:00:00

  • Parents' views and experiences when their preschool child is identified as overweight: a qualitative study in primary care.

    abstract:BACKGROUND:Prevalence of overweight in children has increased significantly in many countries in the past decades. Few parents identify their own children as overweight, especially very young children. Motivating parents is difficult, and interventions to attain normal weight often fail. OBJECTIVE:To explore parents' ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmt056

    authors: Toftemo I,Glavin K,Lagerløv P

    更新日期:2013-12-01 00:00:00

  • Evaluating pharmacist input into the pharmaceutical care of patients in dispensing medical practices in remote and rural areas of Scotland.

    abstract:Background:The Highlands and the Western Isles are the two most remote and rural areas of Scotland, with many medical practices in areas where pharmacies would not be viable. Recent regulations state that that dispensing medical practices in these areas must receive pharmacist support for patients who would benefit. O...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmx014

    authors: Stewart D,Anthony B,Morrison C,MacRae Y,Dixon L,Friel E,Yoong E,Cunningham S,MacLure K

    更新日期:2017-08-01 00:00:00

  • Tests for Helicobacter pylori infection: a critical appraisal from primary care.

    abstract:BACKGROUND:Testing of patients for Helicobacter pylori infection is common in primary care settings. The accuracy of such tests has been assessed and critical appraisal of this literature can inform the clinical management of patients suspected of being infected with H. pylori METHODS:Literature evaluating the accurac...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/17.suppl_2.s12

    authors: Roberts AP,Childs SM,Rubin G,de Wit NJ

    更新日期:2000-08-01 00:00:00

  • Understanding risk: women's perceived risk of menopause-related disease and the value they place on preventive hormone replacement therapy.

    abstract:OBJECTIVES:The aims of this study were to determine women's perceived risk of menopause-related disease and to understand how this shapes their decisions about taking hormone replacement therapy (HRT) for disease prevention. METHODS:A qualitative study based on analysis of audio-taped semi-structured interviews. The s...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/19.6.591

    authors: Ballard K

    更新日期:2002-12-01 00:00:00

  • GPs' attitudes to minor ailments.

    abstract:BACKGROUND:It is generally considered that a significant proportion of 'inappropriate' demand for GP services is generated by consultations for minor ailments. How GPs manage minor ailments is likely to affect how patients perceive and handle similar illnesses in the future. Whilst this potentially has significant impl...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/18.6.581

    authors: Morris CJ,Cantrill JA,Weiss MC

    更新日期:2001-12-01 00:00:00

  • Validation of self-reported help-seeking, and measurement of the patient interval, for cancer symptoms: an observational study to inform methodological challenges in symptomatic presentation research.

    abstract:BACKGROUND:To improve earlier presentation with potential symptoms of cancer, accurate data are needed on how people respond to these symptoms. It is currently unclear how self-reported medical help-seeking for symptoms associated with cancer by people from the community correspond to what is recorded in their general ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmz047

    authors: Smith SM,Whitaker KL,Cardy AH,Elliott AM,Hannaford PC,Murchie P

    更新日期:2020-02-19 00:00:00

  • The effect of introduction of a guideline on the management of vaginal discharge and in particular bacterial vaginosis in primary care.

    abstract:BACKGROUND:Bacterial vaginosis (BV) is the commonest cause of vaginal discharge, and its association with obstetric and gynaecological complications is being recognized increasingly. It was our impression that BV was poorly understood and underdiagnosed in family practice. OBJECTIVE:The aim of this study was to explor...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/18.3.253

    authors: Langsford MJ,Dobbs FF,Morrison GM,Dance DA

    更新日期:2001-06-01 00:00:00

  • Symptomatic effect of inhaled fenoterol in acute bronchitis: a placebo-controlled double-blind study.

    abstract::The symptomatic effect of inhaled fenoterol, a beta 2-agonist, 0.2 mg 4 times daily for 7 days, was evaluated in 80 patients with acute bronchitis examined at the Chest Clinic, Department of Medicine, University Hospital of Tromsø. Seventy-three patients completed the trial. End-point FEV1 (% predicted) showed a mean ...

    journal_title:Family practice

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/fampra/8.3.216

    authors: Melbye H,Aasebø U,Straume B

    更新日期:1991-09-01 00:00:00

  • Biopsychosocial features of patients with widespread chronic musculoskeletal pain in family medicine clinics.

    abstract:OBJECTIVES:We aimed to describe the clinical and psycho-socio-familial features of patients with widespread chronic musculoskeletal pain (WCMP)/fibromyalgia (FM) in primary care settings. To detect differences and similarities between both 'entities'. METHODS:An observational study was carried out with a newcoming cli...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/14.3.242

    authors: Ruiz Moral R,Muñoz Alamo M,Pérula de Torres L,Aguayo Galeote M

    更新日期:1997-06-01 00:00:00

  • Nurse prescribing in general practice: a qualitative study of job satisfaction and work-related stress.

    abstract:BACKGROUND:Studies examining the impact nurse prescribing have largely focused on the efficacy of the service. It was suggested in pro-prescribing policy arguments that extending the nursing role to include prescribing would increase job satisfaction. This assertion has not been fully explored. OBJECTIVES:To investiga...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmr077

    authors: Cousins R,Donnell C

    更新日期:2012-04-01 00:00:00

  • Parental experiences and attitudes regarding the management of acute otitis media--a comparative questionnaire between Finland and The Netherlands.

    abstract:BACKGROUND:Both treatment guidelines and the amount of antibiotics used for acute otitis media (AOM) vary across western countries. Parental expectations and their awareness of antimicrobial use and resistance, which may also be influenced by the guidelines, are not yet completely known. OBJECTIVE:To compare parental ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmp055

    authors: Tähtinen PA,Boonacker CW,Rovers MM,Schilder AG,Huovinen P,Liuksila PR,Ruuskanen O,Ruohola A

    更新日期:2009-12-01 00:00:00

  • General practitioners' use of health education material. Results from a nationwide survey in Denmark in 1991. The Danish Health Education Study Group.

    abstract::In November 1991 69% of a random sample of 998 Danish general practitioners (GPs) participated in a survey by anonymously filling in a mailed questionnaire concerning the way in which they use health education in their practices. Among the participating GPs, 97% used health education material. The study showed differe...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/11.1.35

    authors:

    更新日期:1994-03-01 00:00:00