Symptomatic effect of inhaled fenoterol in acute bronchitis: a placebo-controlled double-blind study.

Abstract:

:The symptomatic effect of inhaled fenoterol, a beta 2-agonist, 0.2 mg 4 times daily for 7 days, was evaluated in 80 patients with acute bronchitis examined at the Chest Clinic, Department of Medicine, University Hospital of Tromsø. Seventy-three patients completed the trial. End-point FEV1 (% predicted) showed a mean increase of 5.1% in the fenoterol group and 0.5% in the placebo group (p = 0.006). The corresponding decrease in total symptom score after one week was 67% and 51%, respectively (p = 0.06). In a subgroup of 35 patients with either bronchial hyper-responsiveness, wheezes on auscultation or FEV1 less than 80% of predicted at entry, a statistically significant difference in reduction of total symptom score in favour of fenoterol was demonstrated on the second day of the trial. No difference was found in the 38 patients with normal lung findings. Fenoterol was useful when objective signs of bronchial involvement was present and may be applicable to the treatment of acute bronchitis.

journal_name

Fam Pract

journal_title

Family practice

authors

Melbye H,Aasebø U,Straume B

doi

10.1093/fampra/8.3.216

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

216-22

issue

3

eissn

0263-2136

issn

1460-2229

journal_volume

8

pub_type

临床试验,杂志文章,随机对照试验
  • General practitioner consultation after a visit to the emergency department: an observational study.

    abstract:BACKGROUND:Some studies have demonstrated an association between poor continuity of care, high likelihood of 'inappropriate' use of emergency departments (EDs) and avoidable hospitalization. However, we lack data concerning primary care use after an ED visit. OBJECTIVE:Identify the determinants of a visit to the gener...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmy054

    authors: Rotival J,Yordanov Y,Thiebaud PC,Pelletier-Fleury N,Jacquet E,Debuc E,Pateron D,Naouri D

    更新日期:2019-03-20 00:00:00

  • Satisfaction and job stress in general practice.

    abstract::This paper investigates sources of job satisfaction and dissatisfaction in general practice and identifies pressures and difficulties experienced by general practitioners in their work. The study revealed widespread job satisfaction based on three separate (but independent) aspects of general practice: clinical, psych...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/5.2.83

    authors: Branthwaite A,Ross A

    更新日期:1988-06-01 00:00:00

  • Using focus groups in general practice research.

    abstract::Recent years have seen a growing recognition of the appropriateness of qualitative methods in family practice. This has been paralleled by an upsurge of interest in focus group discussions as a method. Drawing on the experience of using focus groups with general practice teams as one component of a multi-method study ...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/12.3.328

    authors: Barbour RS

    更新日期:1995-09-01 00:00:00

  • Nutrition guidance in The Netherlands: the role of the GP in the translation from population strategy to individual approach.

    abstract::An important pitfall of nutritional guidance in medical practice is how to deal with the prevention paradox: a nutritional advice that is good for the population as a whole is not necessarily proven effective for the individual patient. Evidence-based guidelines are needed to support GPs to translate these advices to ...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/cmn074

    authors: Drenthen AJ,Van Binsbergen JJ

    更新日期:2008-12-01 00:00:00

  • Family practitioners' attitudes and knowledge about irritable bowel syndrome: effect of a trial of physician education.

    abstract:BACKGROUND:Primary physicians care for most patients with irritable bowel syndrome (IBS), but data on their attitudes and knowledge about the disorder are limited to research in the UK. OBJECTIVE:The purpose of the present study was to assess US family practitioners' attitudes and knowledge about IBS and determine the...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmg608

    authors: Longstreth GF,Burchette RJ

    更新日期:2003-12-01 00:00:00

  • Arrhythmias in general practice: diagnostic value of patient characteristics, medical history and symptoms.

    abstract:BACKGROUND:Complaints possibly caused by arrhythmias are frequently seen in general practice. It is unclear to what extent such complaints can differentiate between arrhythmias and other pathology in general practice. OBJECTIVES:We aimed to assess the value of symptoms (a) in diagnosing arrhythmias in general practice...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/15.4.343

    authors: Zwietering PJ,Knottnerus JA,Rinkens PE,Kleijne MA,Gorgels AP

    更新日期:1998-08-01 00:00:00

  • Does the continuous use of bronchodilators mask the progression of asthma or chronic bronchitis?

    abstract::Recently, we published data of a 2 year randomized controlled study in which the effects of continuous versus symptomatic bronchodilator treatment in patients with moderate asthma or chronic bronchitis were investigated. The results showed that FEV1 decline in the continuously treated group was significantly larger th...

    journal_title:Family practice

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/fampra/9.4.397

    authors: van Schayck CP,Folgering H,den Otter JJ,Tirimanna P,van Weel C

    更新日期:1992-12-01 00:00:00

  • Development of hypertension in obese subjects seen in general practice.

    abstract::A group of 317 overweight men and 565 overweight women was compared with an age-matched normal control group of 444 men and 627 women in order to establish whether hypertension was more often recorded in the obese group. This was done by analysing the continuous morbidity registration of four general practices with a ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/4.1.11

    authors: Bakx JC,Seidell JC,Deurenberg P,van den Hoogen HJ

    更新日期:1987-03-01 00:00:00

  • A score for assessing the risk of first-time adolescent pregnancy.

    abstract:BACKGROUND:Adolescent pregnancy is an important health issue. Prevention programs are usually aimed at the prevention of repeat pregnancy, ignoring the adolescents at risk of becoming pregnant for the first time. OBJECTIVES:To analyse if socio-economic status, family type and mother's age at first pregnancy are risk f...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmr015

    authors: Santos MI,Rosário F

    更新日期:2011-10-01 00:00:00

  • Climacteric complaints in the community.

    abstract:BACKGROUND:At the onset of the climacteric, healthy middle-aged women present with a variety of complaints, especially in general practice. In these first years of entering the menopause, vaginal blood loss alters from irregular periods to complete amenorrhoea. According to these different menstrual patterns, we can di...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/18.2.189

    authors: Maartens LW,Leusink GL,Knottnerus JA,Smeets CG,Pop VJ

    更新日期:2001-04-01 00:00:00

  • Paired interviews of shared experiences around chronic low back pain: classic mismatch between patients and their doctors.

    abstract:BACKGROUND:current treatments for chronic low back pain (LBP) appear to be inadequate and there are growing calls for new approaches. This study explores the paired interviews of shared experiences among chronic LBP patients and their physicians with the ultimate goal of improving doctor-patient communication and clini...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmq063

    authors: Allegretti A,Borkan J,Reis S,Griffiths F

    更新日期:2010-12-01 00:00:00

  • Association between unexplained hypoalbuminaemia and new cancer diagnoses in UK primary care patients.

    abstract:BACKGROUND:The association between hypoalbuminaemia and a new diagnosis of cancer is as yet unknown. OBJECTIVE:This study aimed to assess whether unexplained hypoalbuminaemia was associated with an increased risk of subsequent new cancer diagnosis within the next 12 months. METHODS:A cohort study was performed using ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmw051

    authors: Merriel SW,Carroll R,Hamilton F,Hamilton W

    更新日期:2016-10-01 00:00:00

  • A randomized controlled trial of an intervention designed to improve the care given in general practice to Type II diabetic patients: patient outcomes and professional ability to change behaviour.

    abstract:AIM:Our objective was to evaluate the effect of training in a patient-centred intervention for GPs and practice nurses on outcomes for patients with Type II diabetes. METHODS:We carried out a randomized controlled trial within general practices as the basis for randomization and a before-and-after design for measures ...

    journal_title:Family practice

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/fampra/15.3.229

    authors: Pill R,Stott NC,Rollnick SR,Rees M

    更新日期:1998-06-01 00:00:00

  • European primary care surveillance networks: their structure and operation.

    abstract:BACKGROUND:In many European countries, primary care surveillance networks play a role in public health surveillance. OBJECTIVES:To update an inventory of surveillance networks, to describe them and to report on their organization and function in a standardized way. To investigate whether and under what conditions thei...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmi118

    authors: Deckers JG,Paget WJ,Schellevis FG,Fleming DM

    更新日期:2006-04-01 00:00:00

  • Detection of emotional problems in the primary care clinic.

    abstract::Emotional problems are an important component of general morbidity in primary care settings. Research on the sensitivity of primary care physicians to such problems is, however, scanty. This study examines the prevalence of emotional problems among 776 patients in primary care clinics in Israel using the GHQ-28 and as...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/7.3.195

    authors: Shiber A,Maoz B,Antonovsky A,Antonovsky H

    更新日期:1990-09-01 00:00:00

  • Sources and implications of dissatisfaction among new GPs in the inner-city.

    abstract:OBJECTIVES:We aimed to examine the factors that were most stressful for new principals in inner-city general practice. In addition, given the concerns about retention of new principals, to ascertain whether high perceived stress translated into regret that they had joined their practice and factors that might protect f...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/16.1.18

    authors: Ashworth M,Armstrong D

    更新日期:1999-02-01 00:00:00

  • U-shaped association between mortality and blood pressure in a thirteen-year prospective study.

    abstract::The present study was performed to investigate the predictive value of casual blood pressure recordings for mortality in a geographically defined population (n = 1917), for which the primary health care services are responsible. Isotonic regression of blood pressure on age was used to define groups with low, medium an...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/3.1.3

    authors: Lindholm L,Lanke J,Bengtsson B

    更新日期:1986-03-01 00:00:00

  • Pathways from symptoms to medical care: a descriptive study of symptom development and obstacles to early diagnosis in brain tumour patients.

    abstract:BACKGROUND:The time between experiencing symptoms and treatment in cancer diseases is a time of insecurity and despair. Brain tumour disease is a severe disease with dramatic manifestations and it is important that this time be kept as short as possible. METHODS:A consecutive sample of 28 patients with malignant gliom...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/16.2.143

    authors: Salander P,Bergenheim AT,Hamberg K,Henriksson R

    更新日期:1999-04-01 00:00:00

  • Impact of study design on recruitment of patients to a primary care trial: an observational time series analysis of the Birmingham Atrial Fibrillation Treatment of the Aged (BAFTA) study.

    abstract:BACKGROUND:recruitment targets to randomized controlled trials (RCTs) are often not met. Many interventions are used to improve recruitment but there is little empirical evidence on whether these approaches work. OBJECTIVE:to examine whether changes to the design and conduct of a primary care-based RCT were associated...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmq050

    authors: Fletcher K,Mant J,Roalfe A,Hobbs FD

    更新日期:2010-12-01 00:00:00

  • Reflections from organization science on the development of primary health care research networks.

    abstract::In the UK, policy changes in primary health care research and development have led to the establishment of primary care research networks. These organizations aim to increase research culture, capacity and evidence base in primary care. As publicly funded bodies, these networks need to be accountable. Organizational s...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/18.5.540

    authors: Fenton E,Harvey J,Griffiths F,Wild A,Sturt J

    更新日期:2001-10-01 00:00:00

  • Post-consultation illness trajectories in children with acute cough and respiratory tract infection: prospective cohort study.

    abstract:Background:Little is known about respiratory tract infection (RTI) severity in children following consultation. Objectives:To investigate post-consultation symptom trajectories in children with acute cough and RTI and whether baseline characteristics predict trajectory group. Methods:Prospective cohort study of 2296 ...

    journal_title:Family practice

    pub_type: 杂志文章,多中心研究

    doi:10.1093/fampra/cmy021

    authors: Wensaas KA,Heron J,Redmond N,Turnbull S,Christensen H,Thornton H,Peters TJ,Blair PS,Hay AD

    更新日期:2018-12-12 00:00:00

  • What is the predictive value of urinary symptoms for diagnosing urinary tract infection in women?

    abstract:OBJECTIVES:Our aim was to determine the probability of correctly diagnosing urinary tract infections (UTIs) from urinary symptoms and signs, studying their sensitivity, specificity and likelihood ratio (LR) when clinical history, signs and reactive strip test results are taken into account. METHODS:An epidemiological ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/20.2.103

    authors: Medina-Bombardó D,Seguí-Díaz M,Roca-Fusalba C,Llobera J,dysuria team.

    更新日期:2003-04-01 00:00:00

  • Evaluating the evidence for the implementation of C-reactive protein measurement in adult patients with suspected lower respiratory tract infection in primary care: a systematic review.

    abstract:BACKGROUND:Excessive prescription of antibiotics in patients with lower respiratory tract infection (LRTI) is common in primary care and might be reduced by rapid point-of-care (POC) C-reactive protein (CRP) testing. However, the exact benefits of this test are unclear. OBJECTIVE:To review the available evidence for t...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/cmr119

    authors: Engel MF,Paling FP,Hoepelman AI,van der Meer V,Oosterheert JJ

    更新日期:2012-08-01 00:00:00

  • Results, barriers and enablers in atrial fibrillation case finding: barriers in opportunistic atrial fibrillation case finding-a cross-sectional study.

    abstract:BACKGROUND:Atrial fibrillation (AF) is often asymptomatic, and screening is not routinely undertaken. OBJECTIVE:Evaluate the feasibility and effectiveness of a population-based case finding program and to identify the enablers of and/or barriers to its implementation. METHODS:We conducted a cross-sectional study of a...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmaa023

    authors: Ballesta-Ors J,Clua-Espuny JL,Gentille-Lorente DI,Lechuga-Duran I,Fernández-Saez J,Muria-Subirats E,Blasco-Mulet M,Lorman-Carbo B,Alegret JM

    更新日期:2020-09-05 00:00:00

  • Error and safety in primary care: no clear boundaries.

    abstract::This paper examines the notions of adverse events, error, critical incidents and safety from the specific viewpoint of primary care. We conclude that each term can be defined, but existing work which we reviewed uses many of the terms interchangeably. We recognise that trying to access medical error objectively within...

    journal_title:Family practice

    pub_type: 杂志文章,评审

    doi:10.1093/fampra/cmg302

    authors: Jacobson L,Elwyn G,Robling M,Jones RT

    更新日期:2003-06-01 00:00:00

  • Biopsychosocial features of patients with widespread chronic musculoskeletal pain in family medicine clinics.

    abstract:OBJECTIVES:We aimed to describe the clinical and psycho-socio-familial features of patients with widespread chronic musculoskeletal pain (WCMP)/fibromyalgia (FM) in primary care settings. To detect differences and similarities between both 'entities'. METHODS:An observational study was carried out with a newcoming cli...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/14.3.242

    authors: Ruiz Moral R,Muñoz Alamo M,Pérula de Torres L,Aguayo Galeote M

    更新日期:1997-06-01 00:00:00

  • Achieving involvement: process outcomes from a cluster randomized trial of shared decision making skill development and use of risk communication aids in general practice.

    abstract:BACKGROUND:A consulting method known as 'shared decision making' (SDM) has been described and operationalized in terms of several 'competences'. One of these competences concerns the discussion of the risks and benefits of treatment or care options-'risk communication'. Few data exist on clinicians' ability to acquire ...

    journal_title:Family practice

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/fampra/cmh401

    authors: Elwyn G,Edwards A,Hood K,Robling M,Atwell C,Russell I,Wensing M,Grol R,Study Steering Group.

    更新日期:2004-08-01 00:00:00

  • Sources of information about new drugs and attitudes towards drug prescribing: an international study of differences between primary care physicians.

    abstract::Doctors in different countries completed a questionnaire relating to the importance they attributed to eight possible sources of information about a new drug, their estimation of patients' expectations of the doctor prescribing drugs under specific circumstances and their therapeutic response to common clinical genera...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/4.2.123

    authors: Hull FM,Marshall T

    更新日期:1987-06-01 00:00:00

  • Consultations involving people with congenital disabilities: factors that help or hinder giving care.

    abstract:BACKGROUND:Previous studies have suggested that the attitudes of health professionals towards people with disability may be as negative as those of society. Further, even positive attitudes may not always be reflected in the health professional's behaviour. OBJECTIVE:The aim of this study was to examine GPs' (registra...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/18.4.419

    authors: Muir EH,Ogden J

    更新日期:2001-08-01 00:00:00

  • The narrative approach as an effective single intervention in functional somatic symptoms in a multi-disciplinary referral clinic for primary care frequent attenders.

    abstract::Mental health problems are underdiagnosed in general practice, primarily because they are often somatized and the patient reports only physical symptoms. These somatized symptoms are responsible for a large percentage of the frequent attenders in general practice. Palpitations are among those somatized symptoms. Here ...

    journal_title:Family practice

    pub_type: 杂志文章

    doi:10.1093/fampra/cmh618

    authors: Matalon A,Nachmani T,Rabin S,Maoz B

    更新日期:2005-02-01 00:00:00