Pathogens and glioma: a history of unexpected discoveries ushering in novel therapy.

Abstract:

:In the late 19th century, Dr. William B. Coley introduced the theory that infections may aid in the treatment of malignancy. With the creation of Coley's toxin, reports of remission during viral illnesses for systemic malignancies soon emerged. A few decades after this initial discovery, Austrian physicians performed intravascular injections of Clostridium to induce oncolysis in patients with glioblastoma. Since then, suggestions between improved survival and infectious processes have been reported in several patients with glioma, which ultimately marshaled the infamous use of intracerebral Enterobacter. These early observations of tumor regression and concomitant infection piloted a burgeoning field focusing on the use of pathogens in molecular oncology.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Shah AH,Jusué-Torres I,Ivan ME,Komotar RJ,Kasahara N

doi

10.3171/2016.12.JNS162123

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

1139-1146

issue

4

eissn

0022-3085

issn

1933-0693

pii

2016.12.JNS162123

journal_volume

128

pub_type

历史文章,杂志文章,评审
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    abstract:OBJECT:The objective of the present study was to perform a prospective evaluation of the potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin sodium and irradiation using a 664-nm semiconductor laser in patients with primary malignant parenchymal brain tumors. METHODS:In 27 patie...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.3171/2013.7.JNS13415

    authors: Muragaki Y,Akimoto J,Maruyama T,Iseki H,Ikuta S,Nitta M,Maebayashi K,Saito T,Okada Y,Kaneko S,Matsumura A,Kuroiwa T,Karasawa K,Nakazato Y,Kayama T

    更新日期:2013-10-01 00:00:00

  • Transplacental transmission of metastatic melanoma to the posterior fossa. Case report.

    abstract::The authors describe the first documented case of transplacental transmission of metastatic melanoma to the neuraxis. The patient was a 7-month-old boy who presented with signs and symptoms of elevated intracranial pressure. Magnetic resonance imaging revealed an inhomogeneously enhancing posterior fossa mass measurin...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2005.103.2.0191

    authors: Trumble ER,Smith RM,Pearl G,Wall J

    更新日期:2005-08-01 00:00:00

  • Neurotransmitter release from high-frequency stimulation of the subthalamic nucleus.

    abstract:OBJECT:High-frequency stimulation (HFS) delivered through implanted electrodes in the subthalamic nucleus (STN) has become an established treatment for Parkinson disease (PD). The precise mechanism of action of deep brain stimulation (DBS) in the STN is unknown, however. In the present study, the authors tested the hyp...

    journal_title:Journal of neurosurgery

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    doi:10.3171/jns.2004.101.3.0511

    authors: Lee KH,Chang SY,Roberts DW,Kim U

    更新日期:2004-09-01 00:00:00

  • The effect of single-application topical ophthalmic anesthesia in patients with trigeminal neuralgia. A randomized double-blind placebo-controlled trial.

    abstract::To evaluate the reported benefit of ipsilateral single-application ophthalmic anesthetic eyedrops in patients with typical trigeminal neuralgia, a randomized double-blind placebo-controlled trial was performed. Forty-seven patients were randomly assigned to receive two drops of either proparacaine (25 cases) or saline...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3171/jns.1994.80.6.0993

    authors: Kondziolka D,Lemley T,Kestle JR,Lunsford LD,Fromm GH,Jannetta PJ

    更新日期:1994-06-01 00:00:00

  • Stereotactic radiosurgery for residual neurocytoma. Report of four cases.

    abstract::The purpose of this report was to review the results of stereotactic radiosurgery in the management of patients with residual neurocytomas after initial resection or biopsy procedures. Four patients underwent stereotactic radiosurgery for histologically proven neurocytoma. Clinical and imaging studies were performed t...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2001.95.5.0879

    authors: Tyler-Kabara E,Kondziolka D,Flickinger JC,Lunsford LD

    更新日期:2001-11-01 00:00:00

  • Influence of surgical or endovascular treatment on visual symptoms caused by intracranial aneurysms: single-center series and systematic review.

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    journal_title:Journal of neurosurgery

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    authors: Schuss P,Güresir E,Berkefeld J,Seifert V,Vatter H

    更新日期:2011-10-01 00:00:00

  • Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factors.

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    pub_type: 杂志文章

    doi:10.3171/spi.2002.97.1.0040

    authors: Kandziora F,Bail H,Schmidmaier G,Schollmeier G,Scholz M,Knispel C,Hiller T,Pflugmacher R,Mittlmeier T,Raschke M,Haas NP

    更新日期:2002-07-01 00:00:00

  • Medical treatment decision making after total avulsion brachial plexus injury: a qualitative study.

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    journal_title:Journal of neurosurgery

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    doi:10.3171/2015.2.JNS132686

    authors: Franzblau LE,Maynard M,Chung KC,Yang LJ

    更新日期:2015-06-01 00:00:00

  • Conducted somatosensory evoked potentials during spinal surgery. Part 1: control conduction velocity measurements.

    abstract::Intraoperative recordings of conducted bipolar epidural somatosensory evoked potentials (SEP's) generated by unilateral common peroneal nerve stimulation have been obtained in 27 patients. The SEP's were multiphasic, 0.3 to 1.5 microV in amplitude, and recorded in 100% of patients with normal cords or in patients with...

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    pub_type: 杂志文章

    doi:10.3171/jns.1982.57.3.0349

    authors: Macon JB,Poletti CE

    更新日期:1982-09-01 00:00:00

  • Radiosurgery and radiotherapy: observations and clarifications.

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2004.101.4.0585

    authors: Kondziolka D,Lunsford LD,Loeffler JS,Friedman WA

    更新日期:2004-10-01 00:00:00

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2005.103.4.0681

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    更新日期:2005-10-01 00:00:00

  • Body position and cerebrospinal fluid pressure. Part 2: clinical studies on orthostatic pressure and the hydrostatic indifferent point.

    abstract::Lumbar cerebrospinal fluid (CSF) pressure was recorded in 116 adult neurosurgical patients in the lateral and sitting positions. The level of zero CSF pressure while in the sitting position (ZPS) and hydrostatic indifferent point (HIP) for lateral and sitting positions were determined and referred to the craniospinal ...

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    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.6.0698

    authors: Magnaes B

    更新日期:1976-06-01 00:00:00

  • Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease.

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    pub_type: 杂志文章

    doi:10.3171/jns.2005.102.1.0080

    authors: Yasuhara T,Shingo T,Muraoka K,Kobayashi K,Takeuchi A,Yano A,Wenji Y,Kameda M,Matsui T,Miyoshi Y,Date I

    更新日期:2005-01-01 00:00:00

  • A randomized placebo-controlled double-blind trial of nimodipine after SAH in monkeys. Part 1: Clinical and radiological findings.

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    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.6.1167

    authors: Espinosa F,Weir B,Overton T,Castor W,Grace M,Boisvert D

    更新日期:1984-06-01 00:00:00

  • Inducing transient language disruptions by mapping of Broca's area with modified patterned repetitive transcranial magnetic stimulation protocol.

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    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2013.11.JNS13952

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  • Long-term follow-up results of intentional 2-stage Gamma Knife surgery with an interval of at least 3 years for arteriovenous malformations larger than 10 cm³.

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    更新日期:2012-12-01 00:00:00

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    authors: Pülhorn H,Pesic-Smith J,Cowley P,Murphy M

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    pub_type: 评论,杂志文章

    doi:10.3171/2016.2.JNS151983

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    pub_type: 杂志文章

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    authors: Lewis AI,Tomsick TA,Tew JM Jr,Lawless MA

    更新日期:1996-03-01 00:00:00

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    pub_type: 杂志文章,meta分析,评审

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  • Neurostimulation for chronic noncancer pain: an evaluation of the clinical evidence and recommendations for future trial designs.

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    doi:

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    authors: Tanaka Y,Sakamoto K,Kobayashi S,Kobayashi N,Muraoka S

    更新日期:1988-02-01 00:00:00