A mathematical model of survival in a newly inserted ventricular shunt.

Abstract:

OBJECT:The object of this study was to mathematically model the prognosis of a newly inserted shunt in pediatric or adult patients with hydrocephalus. METHODS:A structured search was performed of the English-language literature for case series reporting shunt failure, patient mortality, and shunt removal rates after shunt insertion. A metaanalytic model was constructed to pool data from multiple studies and to predict the outcome of a shunt after insertion. Separate models were used to predict shunt survival rates for children (patients < 17 years old) and adults. RESULTS:Shunt survival rates in children and adults were calculated for 1 year (64.2 and 80.1%, respectively), 5 years (49.4 and 60.2%, respectively), and the median (4.9 and 7.3 years, respectively). The longer-term rates predicted by the model agree closely with those reported in the literature. CONCLUSIONS:This model gives a comprehensive view of the fate of a shunt for hydrocephalus after insertion. The advantages of this model compared with Kaplan-Meier survival curves are discussed. The model used in this study may provide useful prognostic information and aid in the early evaluation of new shunt designs and techniques.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Stein SC,Guo W

doi

10.3171/PED-07/12/448

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

448-54

issue

6 Suppl

eissn

0022-3085

issn

1933-0693

journal_volume

107

pub_type

杂志文章,meta分析,评审
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    pub_type: 杂志文章,随机对照试验

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