Treatment of Pediatric IgG4-Related Orbital Disease With TNF-α Inhibitor.

Abstract:

:The authors describe a 9-year-old female who presented with swelling, proptosis, and tenderness of the right upper eyelid and MRI imaging demonstrating right lacrimal gland enlargement. After failing treatment with corticosteroids, the patient underwent a biopsy that was consistent with IgG4-related orbital disease. She was subsequently successfully treated with adalimumab (TNF-α inhibitor). This is the first case report of the successful use of a TNF-α inhibitor for the treatment of IgG4-related orbital disease in a child.

authors

Jalaj S,Dunbar K,Campbell A,Kazim M

doi

10.1097/IOP.0000000000000959

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

e10-e12

issue

1

eissn

0740-9303

issn

1537-2677

journal_volume

34

pub_type

杂志文章
  • Lodged intracanalicular plugs as a cause of lacrimal obstruction.

    abstract:PURPOSE:To evaluate the complications and success of treatment of migrated or lodged intracanalicular and punctal plugs. METHODS:A retrospective chart review of all cases having either a dacryocystorhinostomy or surgical removal of an intracanalicular or punctal plug from 1992 to 2006, in a single physician referral o...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e318031d62a

    authors: Mazow ML,McCall T,Prager TC

    更新日期:2007-03-01 00:00:00

  • Primary intraosseous hemangioma of the orbit. Report of a case and review of literature.

    abstract::Orbital intraosseous hemangiomas are rare entities, with only 15 previously reported. We review these and present our own. They are benign, vascular tumors, typically found in the frontal, ethmoid, or zygomatic bones. They tend to present in the 4th or 5th decades as a mildly painful orbital rim mass. Ocular findings ...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/00002341-198912000-00004

    authors: Zucker JJ,Levine MR,Chu A

    更新日期:1989-01-01 00:00:00

  • The pathophysiology of the anophthalmic socket. Part II. Analysis of orbital fat.

    abstract::The pathophysiologic mechanisms responsible for the clinical features of the anophthalmic socket are poorly understood. Atrophy of orbital fat has been thought to be a major contributing cause of enophthalmos and the superior sulcus deformities that develop after enucleation, but it has never been demonstrated histopa...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-199006000-00002

    authors: Kronish JW,Gonnering RS,Dortzbach RK,Rankin JH,Reid DL,Phernetton TM,Pitts WC,Berry GJ

    更新日期:1990-01-01 00:00:00

  • Ocular Considerations in Face Transplantation: Report of 2 Cases and Review of the Literature.

    abstract:PURPOSE:Periorbital injuries are common in face transplantation (FT) candidates. It is therefore essential that the ophthalmologist play a central role in the multidisciplinary treatment of these patients. In this study, the authors perform a comprehensive review of all procedures involving periorbital components, prov...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/IOP.0000000000001296

    authors: Greenfield JA,Kantar RS,Rifkin WJ,Sosin M,Diaz-Siso JR,Patel P,Fleming JC,Iliff NT,Lee BW,Rodriguez ED

    更新日期:2019-05-01 00:00:00

  • Orbital Myositis as Both a Presenting and Associated Extraintestinal Sign of Crohn's Disease.

    abstract::Orbital myositis is a rare extraintestinal manifestation of inflammatory bowel disease and has been reported to occur at variable times relative to gastrointestinal symptoms, including years before, concurrently to, and years after the gastrointestinal diagnosis. Here, the authors report 3 cases of Crohn's disease ass...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000000475

    authors: Vargason CW,Mawn LA

    更新日期:2017-05-01 00:00:00

  • Orbital dermoid cysts presenting as subconjunctival fat droplets.

    abstract::The authors report 3 cases of orbital dermoid cysts presenting with subconjunctival fat droplets. Three female patients were evaluated for conjunctival injection and yellowish granular material lying under the bulbar conjunctiva in the left eye. Slit-lamp examination showed a number of subconjunctival fat droplets in ...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e31817e91e4

    authors: Jung BY,Kim YD

    更新日期:2008-07-01 00:00:00

  • Comprehensive, combined anterior and transcaruncular orbital approach to medial canthal ligament plication.

    abstract:PURPOSE:To assess the efficacy of a comprehensive technique for correction of severe punctal and medial lower eyelid ectropion and lower eyelid retraction associated with medial canthal ligament (MCL) laxity. METHODS:A comprehensive technique that plicates the anterior and posterior crura of the MCL was performed on 8...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e3181469e3c

    authors: Demirci H,Hassan AS,Elner SG,Boehkle C,Elner VM

    更新日期:2007-09-01 00:00:00

  • Computed tomography in the management of orbital cellulitis from an imbedded eye prosthesis.

    abstract::Computed tomography (CT) is far superior to plain radiography or xeroradiography in the detection of orbital foreign bodies and in defining altered anatomic relationships in this region. We present a case in which CT was instrumental in the management of orbital cellulitis in a patient who had forgotten that an eye pr...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-198501030-00006

    authors: Pope TL Jr,Apesos J

    更新日期:1985-01-01 00:00:00

  • Surgical management of lower-lid basal cell carcinoma involving the medial canthus: a modification of the Mustarde cheek rotation flap.

    abstract::The Mustarde cheek rotation flap has proved to be an extremely successful and reliable technique for repairing large defects of the lower lid. However, when a stump of normal, lash-bearing lid margin remains on the advancing edge of the flap, it does not seem appropriate to insert it into a defect that extends more me...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-199809000-00012

    authors: Rao GP,Frank HJ

    更新日期:1998-09-01 00:00:00

  • Double silicone intubation as treatment for persistent congenital nasolacrimal duct obstruction.

    abstract:PURPOSE:The great majority of children with nasolacrimal duct (NLD) obstruction are successfully treated with probing or conventional silicone tube intubation. A small percentage of patients fail to have their NLD obstruction resolved with these procedures and require dacryocystorhinostomy (DCR). This study was conduct...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.IOP.0000103004.71978.0C

    authors: Mauffray RO,Hassan AS,Elner VM

    更新日期:2004-01-01 00:00:00

  • Lacrimal Gland Botulinum Toxin Injection Versus Simple Glandular Needling: Histopathological and Electron Microscopic Evidence and Potential Clinical Implications.

    abstract:PURPOSE:To investigate the histopathological and ultrastructural changes in the lacrimal glands (LGs) of rabbits following either botulinum toxin (BTX) injection or simple glandular needling. METHODS:Twenty-four LGs of 24 eyes of 12 healthy New Zealand white rabbits were included in the study. Of these, 4 LGs of 4 eye...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000001528

    authors: Trakos N,Singh S,Mishra DK,Ali MJ

    更新日期:2020-05-01 00:00:00

  • Management of Orbital and Periocular Vascular Anomalies.

    abstract:PURPOSE:To review the treatment modalities available to clinicians who treat orbital and periocular vascular anomalies, with a focus on newer approaches. METHODS:The authors' experience, along with a literature review, was used to provide a concise summary of the available approaches to the treatment of periocular vas...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/IOP.0000000000000504

    authors: Stacey AW,Gemmete JJ,Kahana A

    更新日期:2015-11-01 00:00:00

  • Recurrent infarction of sphenoid bone with subperiosteal collection in a child with sickle cell disease.

    abstract::Infarction of the orbital bone in patients with sickle cell disease is very rare. The authors report a young boy who presented twice with marked acute proptosis and eyelid swelling of the right eye resulting from infarction in the greater wing of the sphenoid bone accompanied by an orbital subperiosteal collection. Th...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e318203d275

    authors: Alsuhaibani AH,Marzouk MA

    更新日期:2011-09-01 00:00:00

  • Localizing the Lost Rectus Muscle Using the Connective Tissue Framework: Revisiting the Tunnel Technique.

    abstract:PURPOSE:To describe a technique for localizing a lost rectus muscle during strabismus or retinal surgery or following trauma. METHODS:In this single center, retrospective chart review, 5 patients were identified between January 2012 and June 2016 with a lost rectus muscle; 3 during strabismus surgery and 2 post trauma...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000000944

    authors: Jordan DR,Stoica B,Dutton JJ

    更新日期:2017-11-01 00:00:00

  • Ocular adnexal injury and complications in orbital dog bites.

    abstract::Orbital dog bites, though statistically uncommon, occur most frequently in children and are associated with severe ocular adnexal injury. Of 16 victims, two-thirds were under 10 and over half under 5 years of age. The wounds consisted of numerous periorbital punctures, and in most cases, full-thickness lid lacerations...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-198703040-00002

    authors: Gonnering RS

    更新日期:1987-01-01 00:00:00

  • Kindler syndrome causing severe cicatricial ectropion.

    abstract::A 32-year-old female with Kindler syndrome presented with a 5-year history of lower eyelid malposition, corneal exposure, and recurrent erosions. Severe anterior lamellar cicatricial changes were noted bilaterally, with bilateral lower eyelid ectropion and retraction. Tarsal eversion was noted on the left lower eyelid...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e3181c4dff6

    authors: Lelli GJ Jr

    更新日期:2010-09-01 00:00:00

  • Allergic Eyelid Dermatitis as the Sole Manifestation of Gold Hypersensitivity.

    abstract::Gold hypersensitivity is a cause of periorbital dermatitis that often presents as a diagnostic challenge for many ophthalmologists. Six female patients are described as presenting with isolated bilateral periorbital dermatitis. Main symptoms included itching (3/6), eyelid redness (3/6), and drooping eyelids (3/6) for ...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000000783

    authors: McDaniel LM,Couch SM

    更新日期:2017-07-01 00:00:00

  • Primary orbital angiosarcoma: a case report.

    abstract:PURPOSE:The pathogenesis, natural history, histopathology, and recommended treatment for orbital angiosarcoma are illustrated and reviewed. METHODS:Case report. RESULTS:A 71-year-old white male presented with bluish discoloration and swelling of the left medial canthal area. A fine needle aspiration and excisional bi...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-199911000-00019

    authors: Siddens JD,Fishman JR,Jackson IT,Nesi FA,Tsao K

    更新日期:1999-11-01 00:00:00

  • Pilosebaceous Malignant Transformation of Dermoid Cyst in the Orbit.

    abstract::Dermoid cysts may occur in the orbit, most commonly in the superolateral area. Malignant transformation of such lesions has been previously reported; however, most turn out to be squamous cell carcinoma. The authors' patient initially presented with mild proptosis and limitation in extraocular movements. Preliminary b...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000001616

    authors: Concepcion-Torio K,Park JW,Woo KI,Suh YL,Kim YD

    更新日期:2020-07-01 00:00:00

  • Progressive infraorbital nerve hypesthesia as a primary indication for blow-out fracture repair.

    abstract::Traumatic blow-out fractures of the orbital floor are a common injury that can lead to significant morbidity. Accepted indications for surgical repair include displaced fractures consisting of a defect > 50% of the orbital floor, extraocular muscle entrapment, and clinically significant enophthalmos. Although infraorb...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-199412000-00010

    authors: Boush GA,Lemke BN

    更新日期:1994-12-01 00:00:00

  • Mesenchymal Chondrosarcoma of the Lacrimal Gland.

    abstract::A 23-year-old woman presented with right-sided painless proptosis that developed in 12 months. MRI studies demonstrated a well-delineated tumorous enlargement of the right lacrimal gland with homogenous signal intensity and compressing the globe. The tumor was removed totally and in 1 piece with the tentative diagnosi...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000001054

    authors: Kiratli H,Deniz Y,Büyükeren B,Gedikoğlu G

    更新日期:2018-05-01 00:00:00

  • Anterior Approach White-Line Advancement: A Hybrid Technique for Ptosis Correction.

    abstract:PURPOSE:To describe the technique of anterior approach white-line advancement for correction of ptosis. METHODS:Retrospective review of consecutive cases that underwent anterior approach white-line advancement for correction of aponeurotic ptosis. In this technique, the posterior surface of the levator aponeurosis (wh...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000000543

    authors: Sagili S

    更新日期:2015-11-01 00:00:00

  • Lower eyelid tightening: a comparative study.

    abstract::Tightening of the lower eyelid is often performed as an adjunct to various lower lid procedures, and many techniques are available. Herein the author describes a simple and effective surgical technique and compares its failure rate with that of full-thickness pentagonal lid resection and lateral tarsal strip technique...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:

    authors: Liu D

    更新日期:1997-09-01 00:00:00

  • Multidetector CT of nasolacrimal canal morphology: normal variation by age, gender, and race.

    abstract:PURPOSE:To accurately characterize anatomical age, gender, and racial differences in normal nasolacrimal canal morphology and to describe a new, accurate technique for measuring nasolacrimal canal parameters based on high-resolution CT. METHODS:The CT images of 72 patients were reviewed retrospectively and grouped acc...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e3182a230b0

    authors: Ramey NA,Hoang JK,Richard MJ

    更新日期:2013-11-01 00:00:00

  • Characterization of human orbital fat and connective tissue.

    abstract::This study was designed to evaluate the characteristics of human orbital fat and connective tissue. Two exenteration specimens were studied by light microscopy with special stains. Four distinct regions were identified on the basis of their connective tissue septa, which contained blood vessels and were composed of el...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-199811000-00004

    authors: Sires BS,Lemke BN,Dortzbach RK,Gonnering RS

    更新日期:1998-11-01 00:00:00

  • Enucleation of blind, painful eyes.

    abstract:PURPOSE:To determine the demographics and results of treatment in patients undergoing enucleation of blind, painful eyes. METHODS:Medical records were reviewed to determine the precipitating cause, preoperative symptoms, prior therapy, and results of treatment in 58 patients in whom enucleation was performed to reliev...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00002341-200009000-00004

    authors: Custer PL,Reistad CE

    更新日期:2000-09-01 00:00:00

  • Panophthalmitis and Visual Loss as a Complication of Acute Dacryocystitis.

    abstract::Acute dacryocystitis causing visual loss due to development of orbital complications like central retinal artery or ophthalmic artery occlusion, retinal vein occlusions, and optic neuritis is rare but a known entity. However, development of scleral abscess and panophthalmitis as a complication of acute dacryocystitis,...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000001686

    authors: Bothra N,Agarwal K,Ali MJ

    更新日期:2020-11-01 00:00:00

  • Orbital metastasis from medullary thyroid carcinoma.

    abstract::A 46-year-old woman with known multiple endocrine neoplasia type 2A was referred for evaluation of left-sided progressive diplopia and proptosis. She was given the presumptive diagnosis of progressive thyroid-associated orbitopathy. Clinical examination revealed significant proptosis and restricted motility of the lef...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0b013e31818b751d

    authors: Seiff BD,Seiff SR

    更新日期:2008-11-01 00:00:00

  • The Effect of Ptosis Surgery on Brow Position and the Utility of Preoperative Phenylephrine Testing.

    abstract:INTRODUCTION:Many reports have suggested that upper eyelid position and brow height can be interdependent; however, the relation is not universally observed. This study aims to understand the prevalence of this phenomenon and examine the utility of phenylephrine testing in predicting brow height change after surgery. ...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000000458

    authors: Rootman DB,Karlin J,Moore G,Goldberg R

    更新日期:2016-05-01 00:00:00

  • What is in a Name? It is Time to Retire the Term "Asian Blepharoplasty".

    abstract:PURPOSE:This perspective explores the term "Asian blepharoplasty" and its socioemotional meaning to some patients. METHODS:N/A. RESULTS:Words have power. The term "Asian blepharoplasty" makes some patients uncomfortable. To our knowledge, it is the only medical descriptor that uses race. CONCLUSIONS:The use of the t...

    journal_title:Ophthalmic plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/IOP.0000000000001903

    authors: Lorden DS,Kim A,Tejawinata F,Samimi DB,Lo CC,Dresner SC,Burnstine MA

    更新日期:2020-12-07 00:00:00