Abstract:
BACKGROUND:An increased incidence of renal cell carcinoma (RCC) has been observed in patients with end-stage renal disease. However, the incidence of this pathological condition has not been studied adequately in kidney transplant candidates. The aim of this study was to examine the incidence of RCC and the clinical, imaging, and pathological characteristics in this population. METHODS:At our institution, the majority of kidney transplant candidates undergo a non-contrast abdominal computerized tomography (CT) scan as a pre-transplant screening evaluation method. We retrospectively reviewed the medical data from 637 patients who were referred to our institution for kidney transplant evaluation during a period of 2 years. Of these, 174 were found ineligible and were excluded from the study; the final population consisted of 463 patients. Radical nephrectomy was proposed and performed in all the patients with findings highly suspicious of malignancy. RESULTS:A total of 20 patients had findings suspicious for kidney malignancy on non-contrast CT scan and underwent a total nephrectomy before transplantation. At the pathological examination, 13 patients had malignant lesions and 4 patients had benign lesions. All patients with malignancy were male, and 9 of 13 patients with malignancy had papillary RCC. CONCLUSIONS:This study confirms the increased incidence of RCC in kidney transplant candidates and underlines the utility of non-contrast CT scan without an intravenous contrast agent as a very useful screening tool in the pre-operative evaluation of kidney transplant candidates. Hence, we recommend the implementation of routine screening with non-contrast CT scan in all kidney transplant candidates who undergo hemodialysis.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Zorbas KA,Karhadkar SS,Lau KN,Di Carlo Adoi
10.1016/j.transproceed.2017.01.087subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1312-1317issue
6eissn
0041-1345issn
1873-2623pii
S0041-1345(17)30346-9journal_volume
49pub_type
杂志文章abstract:OBJECTIVE:The objective of this study was to assess the effects of cardiac rehabilitation on the functional capacity, pulmonary functions, quality of life, and psychological state of patients who had heart failure (HF), heart transplantation (HTx), or a left ventricular assist device (LVAD). METHODS:An 8-week exercise...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.06.009
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2008.09.040
更新日期:2008-11-01 00:00:00
abstract:INTRODUCTION:Although islet isolation and transplantation techniques have improved extensively in recent years, the loss of healthy functional islets is one of the major obstacles in this enterprise. A biostimulatory effect of low-level laser irradiation has been proven on proliferation of some kinds of cells. The aim ...
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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pub_type: 杂志文章
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abstract::The requirement for perioperative stress dose steroids (SDS) in patients on long-term steroid therapy is controversial, but SDS are given during perioperative care. Studies focusing on surrogate outcomes like cortisol levels indicate a possible requirement for SDS, but clinical results are sparse. We retrospectively c...
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2005.12.078
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2018.03.089
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pub_type: 杂志文章,多中心研究
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更新日期:2016-04-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2014.10.029
更新日期:2014-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.transproceed.2014.06.024
更新日期:2014-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
abstract::Radiation-induced osteosarcoma, its metastasis, and cells grown in tissue culture were karyotyped. Both hypodiploid and hyperdiploid stem lines were observed. The hypodiploid line contained 45-55 chromosomes with 10-15 abnormal metacentric and submetacentric chromosomes and one subtelocentric marker. The hyperdiploid ...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-06-01 00:00:00
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pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2006-12-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2008-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.11.023
更新日期:2013-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.06.087
更新日期:2006-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00