Replicative efficiency and pathogenicity of hepatitis B virus e-minus precore variant.

abstract：BACKGROUND AND AIM:Although sporadic non-ampullary duodenal adenoma is speculated to be precancerous lesion, the relationship between adenoma and carcinoma remains unclear due to their rarity. Previous studies on sporadic non-ampullary duodenal epithelial neoplasm (SNADEN) have mainly targeted superficial tumors, like ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsueda K,Kanzaki H,Matsueda K,Nasu J,Yoshioka M,Nakagawa M,Inoue M,Inaba T,Imagawa A,Takatani M,Takenaka R,Suzuki S,Tomoda J,Yagi T,Fujiwara T,Tanaka T,Okada H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Acute-on-chronic liver failure (ACLF) is a clinical entity where there is a potential for reversibility of hepatic dysfunction once the acute hepatic insult resolves. The portal and systemic hemodynamics in ACLF patients to study its relevance in determining the clinical outcomes was studied. METHO...

journal_title：Journal of gastroenterology and hepatology

authors： Garg H,Kumar A,Garg V,Kumar M,Kumar R,Sharma BC,Sarin SK

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness measurement (LSM) with transient elastography is a non-invasive and reliable test for liver fibrosis. However a small proportion of patients may have unreliable LSM or LSM failure. The aim of the present study was to investigate the factors associated with unreliable LSM or LSM failur...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Wong VW,Chim AM,Yiu KK,Chu SH,Li MK,Chan HL

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND AIM:The improvements in surgical technique and perioperative management in the recent decades may warrant revisit for survival outcomes and prognostic factors after liver resection for hepatocellular carcinoma (HCC). This study aimed to analyze the survival outcomes after liver resection for HCC for a co...

journal_title：Journal of gastroenterology and hepatology

authors： Lee EC,Kim SH,Park H,Lee SD,Lee SA,Park SJ

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND AIM:Interleukin (IL)-18 level and association of its two promoter gene polymorphisms at -607 C/A and -137 G/C positions were investigated in Iranian patients with gastrointestinal (GI) cancers. METHODS:232 cases of GI cancers and 312 healthy controls were enrolled. Serum level of IL-18 was measured by e...

journal_title：Journal of gastroenterology and hepatology

authors： Haghshenas MR,Hosseini SV,Mahmoudi M,Saberi-Firozi M,Farjadian S,Ghaderi A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIMS:We identified patients with nonalcoholic fatty liver disease (NAFLD) to determine the predictive value of serum markers to diagnose histological steatohepatitis (NASH). METHODS:Demographic, serological, radiological and histological variables on 95 consecutive patients with NAFLD were recorded. The...

journal_title：Journal of gastroenterology and hepatology

authors： Malik R,Chang M,Bhaskar K,Nasser I,Curry M,Schuppan D,Byrnes V,Afdhal N

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIM:Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model. The aim of the present study was to apply it as a new cytoreductive approach in a mouse model of gastric cancer. METHODS:A total of 43 genetically engineered...

journal_title：Journal of gastroenterology and hepatology

authors： Okabe S,Kodama Y,Cao H,Johannessen H,Zhao CM,Wang TC,Takahashi R,Chen D

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Collagenous sprue (CS) is a rare form of enteropathy that had been reported to be associated with celiac disease (CD) and collagenous colitis (CC). The aim of our study was to compare the clinical features, treatments, and outcomes of CS, CD, and CC. METHODS:All patients with histologic diagnosis of CS, CD,...

journal_title：Journal of gastroenterology and hepatology

authors： Lan N,Shen B,Yuan L,Liu X

更新日期：2017-01-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) has been reported to be detectable in about 10% of gastric carcinomas. We performed a comparative study of endosonographic findings of EBV-positive and -negative early gastric carcinomas. Epstein-Barr virus was detected in 11.8% (four of 34) of endosonographically observed early gastric ca...

journal_title：Journal of gastroenterology and hepatology

authors： Nishikawa J,Yanai H,Mizugaki Y,Takada K,Tada M,Okita K

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND AIM:6-Mercaptopurine (6-MP) and azathioprine (AZA) are widely used as maintenance therapy in children with inflammatory bowel disease (IBD). However, proper 6-thioguanine nucleotide (6-TGN) concentrations in Japanese children with IBD have not been reported. METHODS:This retrospective review examines 32...

journal_title：Journal of gastroenterology and hepatology

authors： Ohtsuka Y,Arai K,Aoyagi Y,Fujii T,Yamakawa Y,Ohtani K,Ikuse T,Baba Y,Inage E,Kudo T,Suzuki R,Nagata S,Shimizu T

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between gastroesophageal reflux disease and sliding hernia is controversial, especially following distal partial gastrectomy in patients with gastric cancer. The aim of this study was to examine the relationship between gastroesophageal reflux disease and sliding hernia of the esoph...

journal_title：Journal of gastroenterology and hepatology

authors： Fujiwara Y,Nakao K,Inoue T,Koishi K,Nishio Y,Yagyu R,Nakagawa K,Yamamura T

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND AIM:Whether an antiviral interferon (IFN)-based therapy (IBT) after curative treatment of hepatocellular carcinoma (HCC) improves the prognosis in patients with hepatitis C virus (HCV)-related HCC remains to be elucidated. METHODS:A total of 178 patients within the Milan criteria underwent curative trea...

journal_title：Journal of gastroenterology and hepatology

authors： Kanogawa N,Ogasawara S,Chiba T,Saito T,Motoyama T,Suzuki E,Ooka Y,Tawada A,Kanda T,Mikami S,Azemoto R,Kaiho T,Shinozaki M,Ohtsuka M,Miyazaki M,Yokosuka O

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:It has been reported that cathepsin E (CTSE) is a non-secretory and intracellular aspartic proteinase found in the superficial epithelial cells of the stomach and that it is also expressed in pancreatic ductal adenocarcinoma. We evaluated the diagnostic value of CTSE in the pancreatic juice in the diagnosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Uno K,Azuma T,Nakajima M,Yasuda K,Hayakumo T,Mukai H,Sakai T,Kawai K

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness (LS), measured by transient elastography, has been validated as a non-invasive surrogate for liver fibrosis. METHODS:We investigated the long-term predictive ability of LS for hepatocellular carcinoma (HCC) development and overall survival in 1146 patients with chronic hepatitis C by...

journal_title：Journal of gastroenterology and hepatology

authors： Nakagomi R,Tateishi R,Masuzaki R,Soroida Y,Iwai T,Kondo M,Fujiwara N,Sato M,Minami T,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Tanaka Y,Otsuka M,Kato N,Moriya K,Ikeda H,Koike K

更新日期：2019-05-01 00:00:00

abstract：:The main purpose of the present study was to demonstrate the incidence of Paneth cells in colorectal tubular adenomas of Japanese descendants in Hawaii. Paneth cells were found in 73 of 322 adenomas (22.7%) of Japanese descendants in Hawaii. The incidence of Paneth cells in adenomas located from the caecum to the tran...

journal_title：Journal of gastroenterology and hepatology

authors： Wada R,Kuwabara N,Suda K

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIM:Multi-detector-row computed tomography (MDCT) has been reported to be a potentially useful modality for detection of the bleeding origin in patients with acute upper massive gastrointestinal (GI) bleeding. The purpose of this study is to investigate the efficacy of MDCT as a routine method for detect...

journal_title：Journal of gastroenterology and hepatology

authors： Miyaoka Y,Amano Y,Ueno S,Izumi D,Mikami H,Yazaki T,Okimoto E,Sonoyama T,Ito S,Fujishiro H,Kohge N,Imaoka T

更新日期：2014-04-01 00:00:00

abstract：:Chronic pancreatitis (CP) is a disease characterized by irreversible destruction and fibrosis of the parenchyma, leading to pancreatic exocrine insufficiency. In developed countries, the etiology for 60% to 70% of CP amongst male patients is alcohol and 25% are classified as idiopathic chronic pancreatitis (ICP). The ...

journal_title：Journal of gastroenterology and hepatology

authors： Reddy DN,Prasad SS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:This study aimed to describe the clinical features, manometric findings, prevalence and incidence of achalasia in Singapore. METHODS:A total of 615 new patients referred for oesophageal manometry between 1989 and 1996 were examined prospectively. Twenty-four men and 25 women fulfilled the manometric and cli...

journal_title：Journal of gastroenterology and hepatology

authors： Ho KY,Tay HH,Kang JY

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND AIM:Recently, microRNAs (miRNA) have been linked to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). First transcribed as pri-miRNA, these molecules are further processed by a complex of endonuclear and cytosolic RNA binding molecu...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma H,Estep M,Birerdinc A,Afendy A,Moazzez A,Elariny H,Goodman Z,Chandhoke V,Baranova A,Younossi ZM

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The classification of gastritis by using the revised Sydney system suggests that there are two types of Helicobacter pylori-related gastritis. The aim of the present study was to examine the risk factors that might be involved in the presence of either atrophic gastritis or intestinal metaplasia of ...

journal_title：Journal of gastroenterology and hepatology

authors： Tsukui T,Kashiwagi R,Sakane M,Tabata F,Akamatsu T,Wada K,Futagami S,Miyake K,Sueoka N,Hirakawa T,Kobayashi M,Fujimori T,Sakamoto C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether the amount of Helicobacter pylori and the extent of gastric metaplasia in the duodenal mucosa play critical roles in the pathogenesis of duodenal ulcer. METHODS:Duodenal and gastric biopsy specimens were obtained from H. pylori-positive patients with duodenal u...

journal_title：Journal of gastroenterology and hepatology

authors： Futami H,Takashima M,Furuta T,Hanai H,Kaneko E

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis B core-related antigen (HBcrAg) has been shown to correlate with various viral markers in chronic hepatitis B, but its role in defining natural history is not well studied. We aimed to investigate the use of HBcrAg to define different phases of chronic hepatitis B. METHODS:Stored residual ...

journal_title：Journal of gastroenterology and hepatology

authors： Chan HLY,Yasuda S,Wong GLH,Tada T,Chan CKM,Kumada T,Tse YK,Wong VWS,Toyoda H

更新日期：2020-04-15 00:00:00

abstract：:Acute cholangitis is associated with significant morbidity and mortality. Endoscopic drainage procedures have been shown to be a safe and effective mode of treatment in acute cholangitis. As there is paucity of large series on endoscopic management of acute cholangitis, a study was performed to evaluate safety and eff...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma BC,Agarwal DK,Baijal SS,Saraswat VA,Choudhuri G,Naik SR

更新日期：1997-12-01 00:00:00

abstract：:A seroepidemiological study was performed to clarify the prevalence of hepatitis delta virus (HDV) infection among the general population in the Irabu islands, Okinawa, Japan. Of 2028 healthy people examined who had received their annual health check-up in 1994-95, 195 (9.6%) were positive for hepatitis B surface anti...

journal_title：Journal of gastroenterology and hepatology

authors： Sakugawa H,Nakasone H,Shokita H,Kawakami Y,Nakachi N,Adaniya H,Mizushima T,Nakayoshi T,Kinjo F,Saito A,Taira M,Takaesu H,Onga N

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Antiviral therapy has not been adequately evaluated in patients with hepatitis C virus (HCV)-related advanced liver disease due to apprehensions of adverse events and intolerance. The titrable dose of interferon (IFN)-alpha and ribavirin was evaluated in a flexible regimen in a pilot study. METHODS:Twenty-f...

journal_title：Journal of gastroenterology and hepatology

authors： Kumar R,Kumar S,Sharma BC,Singh J,Sarin SK

更新日期：2005-04-01 00:00:00

abstract：:The Asia-Pacific Expert Committee on Hepatitis B Management recently reviewed the impact of hepatitis B in the region and assessed the differences and similarities observed in the practical management of the disease in individual Asia-Pacific countries. Hepatitis B is a major health concern in the Asia-Pacific region,...

journal_title：Journal of gastroenterology and hepatology

authors： Mohamed R,Desmond P,Suh DJ,Amarapurkar D,Gane E,Guangbi Y,Hou JL,Jafri W,Lai CL,Lee CH,Lee SD,Lim SG,Guan R,Phiet PH,Piratvisuth T,Sollano J,Wu JC

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) ranks third of all cancer mortalities in Hong Kong. CRC screening can reduce mortality. However, participation in the CRC screening program depends on the knowledge and attitude of the population. The aim of this study is to investigate the knowledge and attitude towards CRC screening...

journal_title：Journal of gastroenterology and hepatology

authors： Wong BC,Chan AO,Wong WM,Hui WM,Kung HF,Lam SK

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Hypothyroidism is commonly thought to cause decreased gastric emptying but is mostly associated with autoimmune disease. In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying stu...

journal_title：Journal of gastroenterology and hepatology

authors： Kao PF,Lin JD,Chiu CT,Hsu HT,See LC,Tzen KY

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND AIM:Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) of unknown etiology. We aimed to identify the etiological agent of CD using a molecular cloning strategy that was particularly focused on identifying agents causing immune abnormalities and infectious agents. METHODS:We constructed a...

journal_title：Journal of gastroenterology and hepatology

authors： Iizuka M,Nakagomi O,Nanjo H,Chiba M,Fukushima T,Sugita A,Sagara S,Horie Y,Watanabe S

更新日期：2012-08-01 00:00:00

abstract：:This study was designed to elucidate the efficacy of University of Wisconsin (UW) solution for preventing liver injury, when used as a hypothermic perfusate infused into the systemic circulation during extended hepatectomy with hepatic inflow occlusion. Adult mongrel dogs (9.5-17.5 kg, n = 14) were subjected to 75% he...

journal_title：Journal of gastroenterology and hepatology

authors： Ohya T,Ohwada S,Kawashima Y,Tanahashi Y,Takahashi T,Ichikawa H,Tomizawa N,Morishita Y

更新日期：1998-08-01 00:00:00