Nested case-control study: hepatocellular carcinoma risk after hepatitis B surface antigen seroclearance.

abstract：BACKGROUND:Diagnosis and management of chronic antibiotic-refractory pouchitis and Crohn's disease of the pouch can be challenging. Pyloric gland metaplasia is a histological feature indicative of chronic mucosal inflammation. Its value in diagnosis and prognosis of pouch disorders has not been investigated. AIM:To as...

journal_title：Alimentary pharmacology & therapeutics

authors： Kariv R,Plesec TP,Gaffney K,Lian L,Fazio VW,Remzi FH,Lopez R,Goldblum JR,Shen B

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The efficacy of each probiotic should be evaluated separately. Previously, we have shown that Lactobacillus GG (LGG) is effective in treating acute gastroenteritis (AGE) in children. AIM:To update our 2007 meta-analysis on the effectiveness of LGG in treating AGE in children. METHODS:The Cochrane Library, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Szajewska H,Skórka A,Ruszczyński M,Gieruszczak-Białek D

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Recent studies in adults have shown that polymeric (whole protein) diets are as effective as semi-elemental and elemental formulae for the induction of remission in small bowel Crohn's disease. Whole protein diets are more palatable and cheaper. There have been no studies confirming efficacy in children. PA...

journal_title：Alimentary pharmacology & therapeutics

authors： Beattie RM,Schiffrin EJ,Donnet-Hughes A,Huggett AC,Domizio P,MacDonald TT,Walker-Smith JA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Coeliac disease (CD), originally thought to be largely confined to Northern Europe and Australasia and uncommon in North America and the Middle East, is now recognised to be equally common in all these countries. It is still thought to be rare in the Orient and Sub-Saharan Africa. AIM:To assess geographical...

journal_title：Alimentary pharmacology & therapeutics

authors： Kang JY,Kang AH,Green A,Gwee KA,Ho KY

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Distal ulcerative colitis may prove to be resistant to steroids and aminosalicylates, but total colectomy is more difficult to justify than in severe extensive colitis. Immunosuppression is of established benefit in generalized colitis, but there are no data available specific to distal disease. AIM:To dete...

journal_title：Alimentary pharmacology & therapeutics

authors： Falasco G,Zinicola R,Forbes A

更新日期：2002-02-01 00:00:00

abstract：:One hundred and twenty-five patients with duodenal ulcer disease were given continuous ranitidine therapy after initial acute healing. Cumulative remission rates indicated that 95% of patients were ulcer-free after 1 year, 89% at 2 years, 81% at 3 years, 70% at 4 years and 60% at 5 and 6 years. Nine patients had a sec...

journal_title：Alimentary pharmacology & therapeutics

authors： Simon B,Schütz E,Müller P,Dixon JS

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:While empiric acid-suppressive therapy for uninvestigated dyspepsia patients with symptoms of epigastric pain or burning is standard practice, it is unknown whether an early response to therapy predicts outcome. AIM:To evaluate whether a 1-w acid suppression trial is effective for predicting 8-w response in...

journal_title：Alimentary pharmacology & therapeutics

authors： van Zanten SV,Flook N,Talley NJ,Vakil N,Lauritsen K,Bolling-Sternevald E,Persson T,Björck E,Svedberg LE,STARS II Study Group.

更新日期：2007-09-01 00:00:00

abstract：:Coeliac disease is a chronic inflammatory condition associated with small intestinal injury that results in the malabsorption of different nutrients. The damaging factor is gluten present in wheat, barley and rye. The diagnosis relies on the clinical picture of the patient, serological markers for coeliac disease, cha...

journal_title：Alimentary pharmacology & therapeutics

authors： Abdulkarim AS,Murray JA

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Guidelines recommend withholding sofosbuvir (SOF) in patients with an estimated glomerular filtration rate (eGFR) of less than 30 mL/min. AIM:To assess the risk of acute kidney injury (AKI) in patients with no renal contraindications for SOF-based treatment. METHODS:This multicenter retrospective observati...

journal_title：Alimentary pharmacology & therapeutics

authors： Maan R,Al Marzooqi SH,Klair JS,Karkada J,Cerocchi O,Kowgier M,Harrell SM,Rhodes KD,Janssen HLA,Feld JJ,Duarte-Rojo A

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease affects 10-35% of the adult population worldwide; there is no consensus on its treatment. Omega-3 fatty acids have proven benefits for hyperlipidaemia and cardiovascular disease, and have recently been suggested as a treatment for non-alcoholic fatty liver disease. AIMS:To ...

journal_title：Alimentary pharmacology & therapeutics

authors： Masterton GS,Plevris JN,Hayes PC

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The duration of Helicobacter pylori eradication regimens has decreased to 1 week with cure rates of over 90%. This can be attributed to the use of triple drug regimens including potent inhibitors of gastric acid secretion and clarithromycin. There is no theoretical reason why shorter regimens should not be p...

journal_title：Alimentary pharmacology & therapeutics

authors： Grimley CE,Penny A,O'sullivan M,Shebani M,Lismore JR,Cross R,Illing RC,Loft DE,Nwokolo CU

更新日期：1999-07-01 00:00:00

abstract：:All vertebrates secrete gastric acid. Acid denatures the proteins in the food and thus makes them more accessible to proteolytic enzymes, and it kills swallowed micro-organisms. Gastric acid plays an important pathogenetic role in peptic ulcer disease and reflux oesophagitis. In these diseases, drugs that inhibit secr...

journal_title：Alimentary pharmacology & therapeutics

authors： Waldum HL,Brenna E,Kleveland PM,Sandvik AK,Syversen U

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), became a global threat to human health. Liver impairment has been frequently reported as a common manifestation, although its clinical significance is still unclear, particularly in pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Garrido I,Liberal R,Macedo G

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Restriction of dietary FODMAP intake can alleviate symptoms in patients with irritable bowel syndrome. Because many FODMAPs have prebiotic actions, there is concern that their dietary restriction leads to dysbiosis with health consequences, and their intake is being encouraged by addition to foods and via su...

journal_title：Alimentary pharmacology & therapeutics

authors： Gibson PR,Halmos EP,Muir JG

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Several studies have explored the effect of non-alcoholic fatty liver disease (NAFLD) on bone mineral density (BMD) and risk of osteoporotic fractures in adults. However, the extent to which NAFLD adversely affects bone health remains uncertain. AIM:To provide a quantitative estimation of the magnitude of t...

journal_title：Alimentary pharmacology & therapeutics

authors： Mantovani A,Dauriz M,Gatti D,Viapiana O,Zoppini G,Lippi G,Byrne CD,Bonnet F,Bonora E,Targher G

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Delta virus (HDV)-related chronic hepatitis is difficult to treat. AIMS:To evaluate the efficacy of lamivudine 100 mg daily on serum HDV-RNA, hepatitis D virus antibodies and alanine aminotransferase levels, liver histology, and on hepatitis B surface antigen seroconversion. METHODS:Thirty-one hepatitis B ...

journal_title：Alimentary pharmacology & therapeutics

authors： Niro GA,Ciancio A,Tillman HL,Lagget M,Olivero A,Perri F,Fontana R,Little N,Campbell F,Smedile A,Manns MP,Andriulli A,Rizzetto M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Population data supporting an association between the autoimmune cholestatic liver diseases, primary biliary cirrhosis and primary sclerosing cholangitis and coeliac disease, is limited and at times contradictory. AIM:To explore the relationship between coeliac disease and both primary biliary cirrhosis and...

journal_title：Alimentary pharmacology & therapeutics

authors： Lawson A,West J,Aithal GP,Logan RF

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) are at increased risk of osteoporosis. A number of studies have emerged in recent years indicating that tumour necrosis factor (TNF) blockade appears to have a beneficial effect on bone mineral density (BMD) in IBD patients. AIMS:To provide a review of the avai...

journal_title：Alimentary pharmacology & therapeutics

authors： Veerappan SG,O'Morain CA,Daly JS,Ryan BM

更新日期：2011-06-01 00:00:00

abstract：AIM:To estimate the cost-effectiveness over a 4-year duration of lamivudine and adefovir dipivoxil for patients with hepatitis B 'e' antigen-negative chronic hepatitis B. METHODS:A decision analysis model has been used to perform a cost-effectiveness analysis of lamivudine and adefovir dipivoxil from the perspective o...

journal_title：Alimentary pharmacology & therapeutics

authors： Buti M,Casado MA,Calleja JL,Salmerón J,Aguilar J,Rueda M,Esteban R

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The guaiac faecal occult blood test (G-FOBT), HemoccultSENSA, is sensitive for significant neoplasms [colorectal cancer (CRC), advanced adenomatous polyps (AAP)], but faulted by non-specificity for human haemoglobin (Hb). Quantified, Hb- specific, immunochemical faecal occult blood tests (I-FOBT) are now use...

journal_title：Alimentary pharmacology & therapeutics

authors： Rozen P,Levi Z,Hazazi R,Waked A,Vilkin A,Maoz E,Birkenfeld S,Niv Y

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:It has been shown that azathioprine prolongs the response to ciclosporin of steroid-refractory ulcerative colitis, but no specific data are available concerning its toxicity in this indication. AIM AND METHODS:The charts of 21 patients with steroid-refractory ulcerative colitis who received azathioprine ove...

journal_title：Alimentary pharmacology & therapeutics

authors： Actis GC,Bresso F,Astegiano M,Demarchi B,Sapone N,Boscaglia C,Rizzetto M

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Abnormal barrier function may be genetically determined in Crohn's disease. AIM:To examine the role of abnormal intestinal permeability in genetic predisposition in multiplex vs. sporadic Crohn's disease families. METHODS:Intestinal permeability was measured in patients, relatives and partners by means of ...

journal_title：Alimentary pharmacology & therapeutics

authors： D'Incà R,Annese V,di Leo V,Latiano A,Quaino V,Abazia C,Vettorato MG,Sturniolo GC

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:In spite of its frequent use in the treatment of irritable bowel disease little is known about mebeverine's mode of action in man. AIM:To examine mebeverine's effect on transit though the gut during lactulose-induced diarrhoea. METHODS:Nine healthy volunteers undertook a two-way randomized crossover study....

journal_title：Alimentary pharmacology & therapeutics

authors： Washington N,Ridley P,Thomas C,Spiller RC,Watts PJ,Wilson CG

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Common risk factors exist in colorectal neoplasia (cancer or adenoma) and coronary artery disease. AIM:To investigate in a retrospective study if there is coexistence of the two events in patients > OR =50 years. METHODS:Computer data on colonoscopies performed on symptomatic patients, the corresponding me...

journal_title：Alimentary pharmacology & therapeutics

authors： Chan AO,Lam KF,Tong T,Siu DC,Jim MH,Hui WM,Lai KC,Yuen MF,Lam SK,Wong BC

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Magnetic resonance entero-colonography enables accurate assessment of ileocolonic Crohn's disease, but the need for bowel cleansing and rectal enema limits considerably its use in daily practice. AIM:We evaluated the accuracy of diffusion-weighted magnetic resonance entero-colonography with neither bowel cl...

journal_title：Alimentary pharmacology & therapeutics

authors： Buisson A,Hordonneau C,Goutte M,Boyer L,Pereira B,Bommelaer G

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Early differentiation of malignant from benign bile duct obstruction is of utmost importance. AIM:To identify biochemical and clinical predictors for malignancy in patients with bile duct obstruction, and establish a predictive model by combining pre-treatment patient characteristics. A web-based applicatio...

journal_title：Alimentary pharmacology & therapeutics

authors： Meister T,Uphoff MA,Heinecke A,Domagk D,Kunsch S,Lindhorst A,Ellenrieder V,Heinzow HS

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The xenobiotic nuclear pregnane X receptor is implicated in many physiological pathways and diseases, including bile acid detoxification and cholestasis. Aim To estimate the contribution of common gene variants of the xenobiotic receptor (pregnane X receptor, PXR) to genetic susceptibility to intrahepatic ch...

journal_title：Alimentary pharmacology & therapeutics

authors： Castaño G,Burgueño A,Fernández Gianotti T,Pirola CJ,Sookoian S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Coeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer. AIM:To compare the prevalence of colorectal adenomas in coeliac disease patients with that in non-coeliac disease controls. METHODS:We identified ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lebwohl B,Stavsky E,Neugut AI,Green PH

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:We have observed an increase in hepatotoxicity (DILI) reporting related to the use of anabolic androgenic steroids (AAS) for bodybuilding. AIM:To characterise phenotype presentation, outcome and severity of AAS DILI. METHODS:Data on 25 cases of AAS DILI reported to the Spanish (20) and Latin-American (5) D...

journal_title：Alimentary pharmacology & therapeutics

authors： Robles-Diaz M,Gonzalez-Jimenez A,Medina-Caliz I,Stephens C,García-Cortes M,García-Muñoz B,Ortega-Alonso A,Blanco-Reina E,Gonzalez-Grande R,Jimenez-Perez M,Rendón P,Navarro JM,Gines P,Prieto M,Garcia-Eliz M,Bessone F,Brahm

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Treatment with interferon-alpha has been shown to be effective in one-third of hepatitis B e antigen-positive chronic hepatitis B patients, but is clinically associated with relevant adverse events. AIM:To investigate the safety of pegylated interferon alpha-2b in 300 hepatitis B e antigen-positive patients...

journal_title：Alimentary pharmacology & therapeutics

authors： van Zonneveld M,Flink HJ,Verhey E,Senturk H,Zeuzem S,Akarca US,Cakaloglu Y,Simon C,So TM,Gerken G,de Man RA,Hansen BE,Schalm SW,Janssen HL,HBV 99-01 Study Group.

更新日期：2005-05-01 00:00:00