Abstract:
BACKGROUND AND PURPOSE:Functional losses near 20% are seen in the operated kidney during partial nephrectomy. Resected healthy margins are small and ischemia time limited in the modern era. We hypothesize that reconstruction following tumor resection is modifiable and a significant cause of renal function injury. MATERIALS AND METHODS:A literature review of Medline and Scopus was performed for all available dates focusing on partial nephrectomy, renal function, and renal reconstruction. An additional review was performed evaluating recent advances in biomarkers of acute kidney injury. RESULTS:Serum creatinine is of limited value in measuring renal preservation during partial nephrectomy. Stimulated glomerular filtration rate can estimate renal reserve, but is more difficult to measure. CT-based three-dimensional measurements provide the ability to isolate ipsilateral functional loss. Newer urinary biomarkers of acute kidney injury such as kidney injury molecule-1 and cell cycle markers are emerging and might help to quantify renal function loss in real time. Most prior research has focused on ischemia and enucleation. However, despite minimizing both, significant renal function losses are still seen. Four retrospective controlled studies were found comparing cortical renorrhaphy to omission of cortical renorrhaphy. Three of the four found a statistical benefit to nonrenorrhaphy with the range of volume or functional loss in those three being 3.8% to 11.5% vs 15.6% to 20.4%. Urine leaks and bleeding complications were similar to reported rates for both groups. CONCLUSION:Studies evaluating renal function preservation after partial nephrectomy should control for reconstructive injury in addition to ischemia time and resected healthy margin. Cortical renorrhaphy is associated with renal volume and functional loss on retrospective studies, which might be especially relevant in the setting of chronic kidney disease or solitary kidney. Newer biomarkers of renal injury should be used when studying predictors of renal injury.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Bahler CD,Sundaram CPdoi
10.1089/end.2016.0055subject
Has Abstractpub_date
2016-05-01 00:00:00pages
S37-41eissn
0892-7790issn
1557-900Xjournal_volume
30 Suppl 1pub_type
杂志文章,评审abstract:: Objective: The aim of this study was to introduce the "ultrathin parenchyma" resection in a robot-assisted partial nephrectomy (RAPN) via the retroperitoneal approach, and to assess the feasibility, security, and effectiveness of this technique. Me...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2019.0698
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The gold standard treatment for upper-tract transitional-cell carcinoma is radical nephroureterectomy, but management of the distal ureter is not standardized. Two treatment options to detach the distal ureter are open cystotomy (OC) and excision of a bladder cuff or transurethral incision of the...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.0374
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients who are undergoing laparoscopic ablative therapy (LAT) are often older with more comorbidities in comparison with patients who are undergoing laparoscopic partial nephrectomy (LPN). A matched control study was performed to compare the surgical and functional outcomes of LPN and LAT. PAT...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2011.0087
更新日期:2011-12-01 00:00:00
abstract::The article entitled, "Mn-porphyrins as novel molecular MRI contrast agents" by Mouraviev et al., published online ahead of print on November 3, 2011 (DOI: 10.1089/end.2011.0133), in its unedited, uncorrected format, is being officially withdrawn from Journal of Endourology. This early version of the manuscript was no...
journal_title:Journal of endourology
pub_type: 撤回出版物
doi:10.1089/end.2011.0133.ret
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have previously shown that men tolerate office flexible cystoscopy better when they simultaneously view the monitor during their procedure. We sought to demonstrate similar effects of distraction on women undergoing rigid office cystoscopy. PATIENTS AND METHODS:100 consecutive women underwent...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2008.0076
更新日期:2008-12-01 00:00:00
abstract::Lumbar ureteral benign stenosis can be managed by laparoscopy. Prevention of repeat strictures after ureteral anastomosis includes the placement of a ureteral catheter. When laparoscopy is used to perform the anastomosis, a second position is needed to insert the Double J stent. We provide a way to place the double pi...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0153
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:It is known that extracorporeal shock wave lithotripsy (SWL) may be improved by increasing cavitation using tandem shock waves. However, fluid is needed for the cavitation to work. The purpose of this research was to evaluate the importance of a fluid-filled expansion chamber in enhancing stone f...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0334
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to examine a large nationwide (United States) sample of emergency department (ED) visits to determine data related to utilization and costs of care for urolithiasis in this setting. METHODS:Nationwide Emergency Department Sample was analyzed from 2006 to 2009. All patients presenting t...
journal_title:Journal of endourology
pub_type: 杂志文章,多中心研究
doi:10.1089/end.2013.0205
更新日期:2013-12-01 00:00:00
abstract::The appeal of laser therapy is rooted in its absence of complications relative to the gold standard of transurethral electroresection. As in any evaluation of a new medical intervention, efficacy must be weighed against the degree of complications that accompany it. Although there has been a relative paucity of litera...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1995.9.183
更新日期:1995-04-01 00:00:00
abstract:PURPOSE:To construct, train, and apply an artificial neural network (ANN) system for prediction of different outcome variables of percutaneous nephrolithotomy (PCNL). We calculated predictive accuracy, sensitivity, and precision for each outcome variable. METHODS:During the study period, all adult patients who underwe...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0791
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To examine the incidence of urinary tract infection (UTI) after flexible cystoscopy (FC) and determine whether prophylactic norfloxacin reduces this incidence compared with placebo. PATIENTS AND METHODS:A double-blind trial was performed, randomizing 234 patients to either 400 mg of norfloxacin or placebo prio...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2005.19.1006
更新日期:2005-10-01 00:00:00
abstract::Bisphosphonates bind renal calculi and inhibit calcium oxalate crystal growth in vitro. We evaluated their ability to inhibit calcium oxalate urolithiasis in a lithogenic rat model. Male Sprague-Dawley rats (four groups, eight rats each) were fed 1.0% ethylene glycol in their drinking water for 6 weeks. All rats had i...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1997.11.1
更新日期:1997-02-01 00:00:00
abstract::Using high-speed photography and acoustic emission measurements, we studied the dynamics of a transient cavitation bubble near a stone surface and the concomitant shockwaves generated during electrohydraulic lithotripsy (EHL). At each spark discharge, a vapor plasma and subsequently a cavitation bubble oscillating aro...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1997.11.55
更新日期:1997-02-01 00:00:00
abstract::The recent evolution of actively deflectable, flexible endoscopes has included the flexible cystoscope. Improvements in optics, deflectability, and the size of the outer sheath and working channel have been accomplished. A superior flexible cystoscope is one with an outer sheath of 16F or less and working channel larg...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1993.7.527
更新日期:1993-12-01 00:00:00
abstract::The surgical treatment of prostatic obstruction associated with a clinically significant bladder diverticulum has classically combined open diverticulectomy with relief of the bladder outlet obstruction. This report demonstrates that this result may be efficiently achieved by performing transurethral surgery followed ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1996.10.545
更新日期:1996-12-01 00:00:00
abstract::Urinary incontinence may be the result of various forms of detrusor overactivity. Several surgical therapies have been devised, but with the exception of procedures to relieve urethral obstruction, none abolishes the overactivity or restores normal micturition. In general, ablative neurosurgery is considered only in p...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.1996.10.213
更新日期:1996-06-01 00:00:00
abstract::Pelvic organ prolapse is a common problem faced by many women, resulting in significant morbidity and negatively impacting quality of life. Sacrocolpopexy can treat women with vaginal vault prolapse, multicompartment prolapse, and/or a history of failed prolapse procedures. The transabdominal sacrocolpopexy has been s...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0388
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Histotripsy is a nonthermal, noninvasive, pulsed ultrasound technology that homogenizes tissue within the targeted volume. From previous experiments, it appeared that the resultant fibrotic response from histotripsy was limited compared with the typical tissue response seen after thermoablation. The object...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0585
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:Morcellation of the adenoma after laser enucleation of the prostate (LEP) is both time-consuming and prone to complications. We have designed a novel polyethylene sack (ProSac) to improve the morcellation process following LEP. Both silicone and cadaver models were utilized to evaluate the safety and effic...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0618
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To compare blind access and totally tubeless percutaneous antegrade removal and pneumatic transurethral ureterolithotripsy for the management of impacted upper-ureteral calculi >1 cm. PATIENTS AND METHODS:Seventy patients (41 male, 29 female) with impacted upper-ureteral calculi >1 cm were selected in randomiz...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2006.20.616
更新日期:2006-09-01 00:00:00
abstract::The authors have developed an ultrasonic aspirator to assist in urologic endoscopic surgery. It appeared that ultrasonic aspiration of bladder tumors was clinically efficient in transurethral surgery. Tumors 1 to 2 cm in diameter could be aspirated completely with this instrument alone. The application of the ultrason...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1994.8.285
更新日期:1994-08-01 00:00:00
abstract:PURPOSE:To evaluate the use of virtual endoscopy (VE) for the investigation of the pelvicaliceal unit and the depiction of its anatomic deformities. PATIENTS AND METHODS:Two study groups were prospectively enrolled in our protocol: ten patients with nonurologic pathologies, and thus without any known deformity of the ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2005.19.37
更新日期:2005-01-01 00:00:00
abstract:: Objective: To assess the safety and efficacy of a novel vacuum-assisted access sheath (VAAS) in minimally invasive percutaneous nephrolithotomy (MPCNL). Materials and Methods: Seventy-five consecutive patients with single renal...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2019.0652
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To determine the composition and the extent of crystalline (and other) encrustation on ureteral catheters inserted under sterile conditions in stone formers, in comparison with catheters of the same type inserted in nonstone formers for the same time but for different clinical reasons. MATERIALS AND METHODS:Fo...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2004.18.550
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Analgesic abuse is a potential cause of end-stage renal disease. Such patients bear an elevated risk of developing malignancies, predominantly transitional-cell carcinoma. We report our experience with laparoscopic nephroureterectomy carried out in patients with analgesic nephropathy to exclude u...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277901753205807
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Current guidelines recommend routine second transurethral resection (TUR) for accurate diagnosis and to prevent understaging of muscle-invasive bladder cancer. We evaluated the diagnostic accuracy of immediate second resection of the tumor bed during initial TUR and its prognostic significance. ...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2011.0576
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with spinal neuropathy are at an increased risk for urolithiasis. Data on percutaneous nephrolithotomy (PCNL) in this population are limited. Our objective is to review our experience in managing stones with PCNL in patients with spinal neuropathy. PATIENTS AND METHODS:Twenty-one patien...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0344
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:During robot-assisted radical prostatectomy (RARP), patients remain in a steep Trendelenburg position. This can cause positioning injuries as well as rhabdomyolysis. The primary diagnostic indicator of rhabdomyolysis is elevated serum creatine kinase (CK). We investigate whether RARP with extende...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0169
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To report the use of the hand-assisted laparoscopic (HAL) technique for removal of a horseshoe kidney in a patient with autosomal dominant polycystic kidney disease (ADPKD). CASE REPORT:Hospital and outpatient records were reviewed for a 65-year-old man with end-stage renal disease secondary to ADPKD who under...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.397
更新日期:2006-06-01 00:00:00
abstract::We herein present the first case in the literature of enucleation of an aldosterone-producing adenoma by laparoscopy. The indication for adrenal-sparing surgery was bilateral adrenal adenoma. The operation turned out to be easier than laparoscopic adrenalectomy. The postoperative course was uneventful, and the patient...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1997.11.145
更新日期:1997-04-01 00:00:00