Abstract：
BACKGROUND:Fungal infection is a rare pathology in the sphenoid sinus, and extension into the pituitary fossa with visual loss has only been described in a few reports in the literature. Following publication of a recent report of pituitary abscess by Candida glabrata, we describe our own experience with a similar pathology. CASE DESCRIPTION:In the present report, we overview a diabetic patient who sustained aspergilloma in his sphenoid sinus with extension to the pituitary fossa. Clinical presentations are discussed along with an emphasis on the role of endoscopic endonasal drainage of the abscess as the mainstay of treatment. Following administration of intravenous amphotericin B for 6 days, endoscopic drainage of the aspergillus abscess was done. Visual acuity improved immediately after the operation. At the 12-month follow-up visit, the improvement in visual acuity was maintained and magnetic resonance imaging showed no recurrence. CONCLUSION:Correction of the underlying immune deficiencies, administration of intravenous antifungal agents perioperatively, endoscopic endonasal drainage of abscess, and a meticulous debridement of necrotic material, followed by a course of oral antifungal medication, comprises the standard treatment protocol for a fungus ball (aspergilloma) of the sphenoid sinus.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Saffarian A,Derakhshan N,Taghipour M,Eghbal K,Roshanfarzad M,Dehghanian Adoi
10.1016/j.wneu.2018.04.054subject
Has Abstractpub_date
2018-07-01 00:00:00pages
159-161eissn
1878-8750issn
1878-8769pii
S1878-8750(18)30770-8journal_volume
115pub_type
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journal_title：World neurosurgery
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