Computer-aided analysis of middle cerebral artery tortuosity: association with aneurysm development.

Abstract:

:OBJECTIVEBlood vessel tortuosity may play an important role in the development of vessel abnormalities such as aneurysms. Currently, however, there are no studies analyzing the impact of brain blood vessel tortuosity on the risk of aneurysm formation. Therefore, the authors performed a computer-aided analysis of middle cerebral artery (MCA) tortuosity, especially among patients diagnosed with MCA aneurysms.METHODSAnatomy of the MCAs of 54 patients with unruptured MCA aneurysms was retrospectively analyzed, as was that of 54 sex-, age-, and vessel side-matched control patients without MCA aneurysms. From medical records, the authors obtained each patient's medical history including previous and current diseases and medications. For each patient, they calculated the following tortuosity descriptors: relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD), and inflection count metric (ICM).RESULTSPatients with an MCA aneurysm had significantly lower RLs (0.75 ± 0.09 vs 0.83 ± 0.08, p < 0.01), SOAMs (0.45 ± 0.10 vs 0.60 ± 0.17, p < 0.01), and PADs (0.34 ± 0.09 vs 0.50 ± 0.17, p < 0.01). They also had significantly higher TIs (0.87 ± 0.04 vs 0.81 ± 0.07, p < 0.01) and ICMs (3.07 ± 1.58 vs 2.26 ± 1.12, p < 0.01). Female patients had significantly higher RLs (0.76 ± 0.11 vs 0.80 ± 0.09, p = 0.03) than male patients.CONCLUSIONSMiddle cerebral artery aneurysm formation is strongly associated with blood vessel tortuosity parameters, which can potentially be used to screen for patients at risk for MCA aneurysm formation.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Kliś KM,Krzyżewski RM,Kwinta BM,Stachura K,Moskała M,Tomaszewski KA

doi

10.3171/2017.12.JNS172114

subject

Has Abstract

pub_date

2018-05-18 00:00:00

pages

1-7

eissn

0022-3085

issn

1933-0693

pii

2017.12.JNS172114

pub_type

杂志文章
  • Intracranial phosphaturic mesenchymal tumors: report of 2 cases.

    abstract::Hypophosphatemia with osteomalacia may be due to a neoplasm that produces fibroblast growth factor 23 (FGF-23), which inhibits phosphate reabsorption in the kidneys. Most of these tumors occur in bone or soft tissue and occasionally in the head, although intracranial occurrence is very rare. This report describes a tu...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/2012.12.JNS12598

    authors: Mathis DA,Stehel EJ Jr,Beshay JE,Mickey BE,Folpe AL,Raisanen J

    更新日期:2013-04-01 00:00:00

  • Induction of hypercontractility in human cerebral arteries by rewarming following hypothermia: a possible role for tyrosine kinase.

    abstract::Induction of hypothermia is used routinely in neurosurgical and cardiovascular operations to protect the brain from ischemic insult. However, despite a plethora of experimental evidence supporting the use of hypothermia to protect the brain from ischemia, clinical experience using deliberate hypothermia in humans has ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.87.3.0431

    authors: Sagher O,Huang DL,Webb RC

    更新日期:1997-09-01 00:00:00

  • Steroids in severe head injury: A prospective randomized clinical trial.

    abstract::This is a prospective randomized study of the efficacy of steroid therapy in patients with severe head injury. One hundred patients were randomized into two equal groups: the steroid group received 5 mg/kg/day of methylprednisolone, and the nonsteroid group received no drug. The groups were similar in their clinical f...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3171/jns.1981.54.5.0596

    authors: Saul TG,Ducker TB,Salcman M,Carro E

    更新日期:1981-05-01 00:00:00

  • Operating room waste: disposable supply utilization in neurosurgical procedures.

    abstract::OBJECTIVE Disposable supplies constitute a large portion of operating room (OR) costs and are often left over at the end of a surgical case. Despite financial and environmental implications of such waste, there has been little evaluation of OR supply utilization. The goal of this study was to quantify the utilization ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.2.JNS152442

    authors: Zygourakis CC,Yoon S,Valencia V,Boscardin C,Moriates C,Gonzales R,Lawton MT

    更新日期:2017-02-01 00:00:00

  • Effectiveness of staged angioplasty for avoidance of cerebral hyperperfusion syndrome after carotid revascularization.

    abstract::OBJECTIVECerebral hyperperfusion syndrome (CHS) is a serious complication after carotid artery stenting (CAS). Staged angioplasty (SAP)-i.e., angioplasty followed by delayed CAS-has been reported as a potential CHS-avoiding procedure. The purpose of this study was to clarify the effectiveness of SAP in avoiding CHS af...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.8.JNS18887

    authors: Hayakawa M,Sugiu K,Yoshimura S,Hishikawa T,Yamagami H,Fukuda-Doi M,Sakai N,Iihara K,Ogasawara K,Oishi H,Ito Y,Matsumaru Y

    更新日期:2019-01-18 00:00:00

  • Phenotypic diversity in patients with craniosynostoses unrelated to Apert syndrome: the role of fibroblast growth factor receptor gene mutations.

    abstract:OBJECT:The goal of this study was to elucidate the genotype-phenotype relationship in syndromic craniosynostoses by analyzing the mutations of the fibroblast growth factor receptor (FGFR) gene and its clinical manifestations in patients, particularly those in atypical cases. METHODS:Twenty patients with craniosynostos...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2005.102.1.0023

    authors: Ito S,Sekido K,Kanno H,Sato H,Tanaka M,Yamaguchi K,Yamamoto I

    更新日期:2005-01-01 00:00:00

  • Modulation of physiological hemostasis by irrigation solution: comparison of various irrigation solutions using a mouse brain surface bleeding model.

    abstract:OBJECT:Intraoperative bleeding often obscures the surgical field and may cause neurological damage. The irrigation fluids used during surgery might affect physiological hemostasis because they modulate the extracellular fluid composition of the bleeding area directly. The authors therefore investigated the influence of...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.7.JNS09561

    authors: Fujita Y,Doi K,Harada D,Kamikawa S

    更新日期:2010-04-01 00:00:00

  • Computerized tomography of peripheral nerve lesions.

    abstract::Nine patients with a peripheral nerve lesion (six intrinsic and three extrinsic) were evaluated with computerized tomography (CT). In all but one instance, the CT scans gave useful information regarding the anatomical location, size, and relationship of the lesion to surrounding structures. These cases illustrate the ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1983.59.1.0131

    authors: Powers SK,Norman D,Edwards MS

    更新日期:1983-07-01 00:00:00

  • Preservation of the arteries around an aneurysm: practical use of oxycellulose. Technical note.

    abstract::The authors describe an intraoperative technique, in which oxycellulose is placed between an aneurysm and its surrounding arteries, allowing a space to be secured for inserting the clip blades without occlusion of the arteries. This method is useful in preserving the blood vessels, especially perforating arteries, aro...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.4.0748

    authors: Kodama N,Matsumoto M,Sasaki T

    更新日期:1995-10-01 00:00:00

  • Immunohistochemical expression of nestin in adenohypophysial vessels during development of pituitary infarction.

    abstract:OBJECTIVES:The aim of this work was to investigate the immunohistochemical expression of nestin, a member of the intermediate filament family, in adenohypophysial vasculature during development and progression of pituitary infarction. METHODS:Forty-five nontumorous adenohypophyses and 34 pituitary adenomas of various ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/108/01/0118

    authors: Salehi F,Kovacs K,Cusimano MD,Horvath E,Bell CD,Rotondo F,Scheithauer BW

    更新日期:2008-01-01 00:00:00

  • Experimental delayed radiation necrosis of the brain. Part 1: Effect of early dexamethasone treatment.

    abstract::The authors have designed an experiment to detect a hitherto unrecognized interaction between high doses of the glucocorticoid, dexamethasone, and brain irradiation. Eighteen juvenile male rhesus monkeys received 1800 rads to the whole brain in 8.5 minutes. For 1 1/2 days before and 10 1/2 days after the irradiation, ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1979.51.5.0587

    authors: Martins AN,Severance RE,Henry JM,Doyle TF

    更新日期:1979-11-01 00:00:00

  • Intracerebral toxoplasmosis in patients with acquired immune deficiency syndrome.

    abstract::The acquired immune deficiency syndrome (AIDS) is a recently described T-cell deficiency predisposing patients to a spectrum of opportunistic infections. Kaposi's sarcoma, and other neoplasms. It appears primarily among homosexual males and intravenous drug abusers, but is now being observed in other groups as well. T...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1983.59.6.0994

    authors: Handler M,Ho V,Whelan M,Budzilovich G

    更新日期:1983-12-01 00:00:00

  • Carbamazepine in the treatment of the flashing pain syndrome.

    abstract::Five patients were seen who described similar rapid shot-like pains that we have called "flashing pain syndrome" and whose pain was relieved by carbamazepine. The pathology of these conditions is not uniform, but the clinical description appears to be specific for an unpleasant condition that will respond dramatically...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.45.1.0049

    authors: Dunsker SB,Mayfield FH

    更新日期:1976-07-01 00:00:00

  • Early history of neurosurgery in Manitoba: threads in the tapestry of world neurosurgery.

    abstract::The author describes the history of neurosurgery in Manitoba, with particular emphasis on events that occurred after his arrival there in 1950. Highlights of global neurosurgery are spliced into the author's reminiscences to anchor the local history with that of neurosurgery as a whole. ...

    journal_title:Journal of neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.3171/jns.1995.82.5.0900

    authors: Parkinson D

    更新日期:1995-05-01 00:00:00

  • Intracranial pressure monitoring with the Neurodur-P epidural sensor: a prospective study in patients with adult hydrocephalus or idiopathic intracranial hypertension.

    abstract:OBJECT:Continuous intracranial pressure (ICP) monitoring using an epidural sensor is a common technique used in selected neurosurgical patients. The aim of this study was to assess the safety and accuracy of the Neurodur-P epidural sensor in the clinical setting. METHODS:The zero drift, as well as the medical and tech...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/108/5/0934

    authors: Poca MA,Martínez-Ricarte F,Sahuquillo J,Lastra R,Torné R,Armengol MS

    更新日期:2008-05-01 00:00:00

  • Superficial peroneal nerve syndrome: an unusual nerve entrapment. Case report.

    abstract::Lower-extremity pain and paresthesia have multiple origins. Early recognition of the symptoms of peripheral nerve entrapment leads to timely treatment and avoids the cost of unnecessary studies. The authors report on a case of superficial peroneal nerve syndrome resulting from nerve herniation through a fascial defect...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.5.820

    authors: Yang LJ,Gala VC,McGillicuddy JE

    更新日期:2006-05-01 00:00:00

  • Association between a black band on the inner membrane of a chronic subdural hematoma on T2*-weighted magnetic resonance images and enlargement of the hematoma.

    abstract:OBJECT:The cause and indication for enlargement of chronic subdural hematomas (CSDHs) have remained unresolved. The authors observed a black band on the inner membrane of a CSDH on T2*-weighted magnetic resonance (MR) images obtained in patients with symptoms. After surgical treatment, the band disappeared. The T2*-wei...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2003.99.5.0824

    authors: Imaizumi T,Horita Y,Honma T,Niwa J

    更新日期:2003-11-01 00:00:00

  • Preliminary evaluation of a novel intraparenchymal capacitive intracranial pressure monitor.

    abstract:OBJECT:Intracranial pressure (ICP) monitors are currently based on fluid-filled, strain gauge, or fiberoptic technology. Capacitive sensors have minimal zero drift and energy requirements, allowing long-term implantation and telemetric interrogation; their application to neurosurgery has only occasionally been reported...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2011.4.JNS101920

    authors: Aquilina K,Thoresen M,Chakkarapani E,Pople IK,Coakham HB,Edwards RJ

    更新日期:2011-09-01 00:00:00

  • Bifrontal decompressive craniectomy in the management of head trauma.

    abstract::Retrospective analysis of 13 patients who had bifrontal decompressive craniectomy for the management of posttraumatic cerebral edema shows a significant decrease in expected mortality, but severe morbidity in the survivors. Only one patient returned to the pretrauma level of neurological function. No correlation could...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1975.42.4.0429

    authors: Venes JL,Collins WF

    更新日期:1975-04-01 00:00:00

  • Cathepsin B and middle cerebral artery occlusion in the rat.

    abstract::Lysosomal proteases, although tightly regulated under physiological conditions, are known to contribute to cell injury after various forms of tissue ischemia have occurred. Because cathepsin B is a prominent lysosomal protease found in brain parenchyma, the authors hypothesized that it may contribute to neuronal cell ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.87.5.0716

    authors: Seyfried D,Han Y,Zheng Z,Day N,Moin K,Rempel S,Sloane B,Chopp M

    更新日期:1997-11-01 00:00:00

  • Temporal lobe epilepsy surgery failures: predictors of seizure recurrence, yield of reevaluation, and outcome following reoperation.

    abstract:OBJECT:The authors provide a systematic analysis of electroclinical characteristics in patients with persistent seizures following temporal lobe epilepsy (TLE) surgery and identify ideal candidates for reoperation. METHODS:The authors retrospectively reviewed the records of 68 adult patients (mean follow-up 8.7 years)...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.8.JNS10180

    authors: Jehi LE,Silveira DC,Bingaman W,Najm I

    更新日期:2010-12-01 00:00:00

  • Surgical treatment of falcotentorial meningiomas: a retrospective review of a single-institution experience.

    abstract:OBJECTIVE:Meningiomas at the falcotentorial junction represent a rare subgroup of complex meningiomas. Debate remains regarding the appropriate treatment strategy for and optimal surgical approach to these tumors, and surgical outcomes have not been well described in the literature. The authors reviewed their single-in...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2019.4.JNS19208

    authors: Zhao X,Belykh E,Przybylowski CJ,Borba Moreira L,Gandhi S,Tayebi Meybodi A,Cavallo C,Valli D,Wicks RT,Nakaji P

    更新日期:2019-08-02 00:00:00

  • Neurosurgical correction of upper brachial plexus birth injuries.

    abstract::The authors review the cases of 116 infants treated consecutively for birth-related brachial plexus injuries. Twenty-eight infants with upper brachial plexus lesions who showed no neurological improvement by 4 months of age were selected for early surgical reconstruction (at a mean age of 5 months). Neurological impro...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1993.79.2.0197

    authors: Laurent JP,Lee R,Shenaq S,Parke JT,Solis IS,Kowalik L

    更新日期:1993-08-01 00:00:00

  • The identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon, and zeta.

    abstract::Levels of protein kinase C (PKC) isoforms in eight human glioblastoma cell lines and two normal human glial cell cultures were determined. Earlier studies identified PKC-alpha and PKC-gamma in these cell lines but PKC-beta was not present. In this study, PKC-epsilon and PKC-zeta are demonstrated immunologically in the...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.81.5.0734

    authors: Xiao H,Goldthwait DA,Mapstone T

    更新日期:1994-11-01 00:00:00

  • The history of neurosurgery at the University of Rochester.

    abstract::The Department of Neurosurgery at the University of Rochester has a long legacy of excellent patient care and innovation in the neurosciences. The department's founder, Dr. William Van Wagenen, was a direct pupil of Harvey Cushing and the first president of the Harvey Cushing Society. His successor, Dr. Frank P. Smith...

    journal_title:Journal of neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.3171/2014.7.JNS132658

    authors: Kimmell KT,Petraglia AL,Bakos R,Rodenhouse T,Maurer PK,Pilcher WH

    更新日期:2014-10-01 00:00:00

  • Therapeutic effects of local delivery of dexamethasone on experimental brain tumors and peritumoral brain edema.

    abstract::To determine if dexamethasone administered by osmotic pump directly to brain tumors would control peritumoral edema and at the same time suppress tumor growth and prolong survival, the authors studied experimental brain tumors produced in 102 rabbits by implanting VX2 carcinoma cells. Of these, 58 animals were separat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1993.79.5.0716

    authors: Ikeda Y,Carson BS,Lauer JA,Long DM

    更新日期:1993-11-01 00:00:00

  • Acrylic spinal fusion. A 20-year clinical series and technical note.

    abstract::Methyl methacrylate (acrylic) was used in fusion techniques in 82 patients, most of whom had metastatic disease, between 1959 and 1979. In all cases the acrylic was used to supplement stabilization with Meurig-Williams stainless steel plates or with wire. In cases involving a decompressive laminectomy and excisional b...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1980.53.5.0606

    authors: Hansebout RR,Blomquist GA Jr

    更新日期:1980-11-01 00:00:00

  • Acute hydrocephalus and death one month after non-surgical treatment for acute cerebellar hemorrhage. Case report.

    abstract::Acute cerebellar hemorrhages, treated medically with subsequent complete recovery, have been designated "benign cerebellar hemorrhages." Ordinarily, acute cerebellar hemorrhage does require early surgical intervention and reported surgical mortality is relatively low (17%) in awake patients with this lesion. Clinical ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1979.50.3.0374

    authors: Brillman J

    更新日期:1979-03-01 00:00:00

  • Hypoglossal-facial nerve side-to-end anastomosis for preservation of hypoglossal function: results of delayed treatment with a new technique.

    abstract::This report describes a new surgical technique to improve the results of conventional hypoglossal-facial nerve anastomosis that does not necessitate the use of nerve grafts or hemihypoglossal nerve splitting. Using this technique, the mastoid process is partially resected to open the stylomastoid foramen and the desce...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.86.2.0203

    authors: Sawamura Y,Abe H

    更新日期:1997-02-01 00:00:00

  • Reversal of experimental delayed cerebral vasospasm by angiotensin-converting enzyme inhibition.

    abstract::Delayed cerebral vasospasm is an important determinant of the clinical outcome after subarachnoid hemorrhage, but its prevention and treatment has met with limited success. Since cerebral arteries were found to be sensitive to the vasoconstrictor effect of angiotensin II, the possibility of angiotensin's contribution ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1981.55.6.0884

    authors: Gavras H,Andrews P,Papadakis N

    更新日期:1981-12-01 00:00:00