Abstract:
BACKGROUND:In recent years, the field of vaccines for diseases such as Human Immunodeficiency Virus (HIV) which take a heavy toll in developing countries has faced major failures. This has led to a call for more basic science research, and development as well as evaluation of new vaccine candidates. Human-animal chimeras, developed with a 'humanized' immune system could be useful to study infectious diseases, including many neglected diseases. These would also serve as an important tool for the efficient testing of new vaccine candidates to streamline promising candidates for further trials in humans. However, developing human-animal chimeras has proved to be controversial. DISCUSSION:Development of human-animal chimeras for vaccine development has been slowed down because of opposition by some philosophers, ethicists and policy makers in the west-they question the moral status of such animals, and also express discomfort about transgression of species barriers. Such opposition often uses a contemporary western world view as a reference point. Human-animal chimeras are often being created for diseases which cause significantly higher morbidity and mortality in the developing world as compared to the developed world. We argue in our commentary that given this high disease burden, we should look at socio-cultural perspectives on human-animal chimera like beings in the developing world. On examination, it's clear that such beings have been part of mythology and cultural descriptions in many countries in the developing world. SUMMARY:To ensure that important research on diseases afflicting millions like malaria, HIV, Hepatitis-C and dengue continues to progress, we recommend supporting human-animal chimera research for vaccine development in developing countries (especially China and India which have growing technical expertise in the area). The negative perceptions in some parts of the west about human-animal chimeras can be used as an opportunity for nurturing important vaccine development research in the developing world.
journal_name
BMC Int Health Hum Rightsjournal_title
BMC international health and human rightsauthors
Bhan A,Singer PA,Daar ASdoi
10.1186/1472-698X-10-8subject
Has Abstractpub_date
2010-05-19 00:00:00pages
8issn
1472-698Xpii
1472-698X-10-8journal_volume
10pub_type
杂志文章abstract:BACKGROUND:In September 2003, the Canadian government committed to developing legislation that would facilitate greater access to affordable medicines for developing countries. Over the course of eight months, the legislation, now known as Canada's Access to Medicines Regime (CAMR), went through a controversial policy ...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-10-1
更新日期:2010-01-04 00:00:00
abstract:BACKGROUND:Women, especially those who marry as children, experience various forms and degrees of exclusion and discrimination. Early marriage is a harmful traditional practice that continues to affect millions around the world. Though it has declined over the years, it is still pervasive in developing countries. In Et...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-020-00249-5
更新日期:2020-12-14 00:00:00
abstract:BACKGROUND:This study explored how employed caregivers experience the interface between child care, parental control and child rights in the context of Children's Homes in Ghana. The focus was on investigating caregiver perceptions of proper child care, their experiences with having to work with child rights principles...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-018-0151-9
更新日期:2018-02-20 00:00:00
abstract:BACKGROUND:Biopiracy - the use of a people's long-established medical knowledge without acknowledgement or compensation - has been a disturbing historical reality and exacerbates the global rich-poor divide. Bioprospecting, however, describes the commercialization of indigenous medicines in a manner acceptable to the l...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-10-S1-S9
更新日期:2010-12-13 00:00:00
abstract:BACKGROUND:Men's participation is crucial to the success of family planning programs and women's empowerment and associated with better outcomes in reproductive health such as contraceptive acceptance and continuation, and safer sexual behaviors. Limited choice and access to methods, attitudes of men towards family pla...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-014-0033-8
更新日期:2014-12-02 00:00:00
abstract:BACKGROUND:Costa Rica, like other developing countries, is experiencing an increasing burden of chronic conditions such as diabetes mellitus (DM), especially among its elderly population. This article has two goals: (1) to assess the level of metabolic control among the diabetic population age >or= 60 years old in Cost...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-8-5
更新日期:2008-05-14 00:00:00
abstract:BACKGROUND:The care and protection of the estimated 143,000,000 orphaned and abandoned children (OAC) worldwide is of great importance to global policy makers and child service providers in low and middle income countries (LMICs), yet little is known about rates of child labour among OAC, what child and caregiver chara...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-11-1
更新日期:2011-01-13 00:00:00
abstract:BACKGROUND:Myanmar/Burma has received increased development and humanitarian assistance since the election in November 2010. Monitoring the impact of foreign assistance and economic development on health and human rights requires knowledge of pre-election conditions. METHODS:From October 2008-January 2009, community-b...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-14-15
更新日期:2014-05-05 00:00:00
abstract:BACKGROUND:Diversity in Europe has both increased and become more complex posing challenges to both national and local welfare state regimes. Evidence indicates specific barriers for migrant, faith and minority ethnic groups when accessing healthcare. However, previous studies of health in diverse cities in European co...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-015-0055-x
更新日期:2015-06-28 00:00:00
abstract:BACKGROUND:One of the main treatment procedures is through medicine prescription. Considering the rising burden of drug costs, we conducted this study to estimate the impoverishing effects of medicine on Iranian households. METHOD:We carried out calculations based on the Iranian National Household Survey for the year ...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-019-0210-x
更新日期:2019-07-31 00:00:00
abstract:BACKGROUND:Persons with Disabilities (PWDs) are a unique group that are often overlooked in many developing countries due to systemic weaknesses, lack of political commitment and inadequate support from government and non-governmental agencies. The population of these individuals is however steadily on the increase and...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-016-0094-y
更新日期:2016-08-08 00:00:00
abstract:BACKGROUND:The health status and lifestyle of migrants is often poorer than that of the general population of their host countries. The Nepalese represent a relatively small, but growing, immigrant community in the UK, about whom very little is known in term of public health. Therefore, our study examined the health an...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-8-6
更新日期:2008-05-23 00:00:00
abstract:BACKGROUND:There are various harmful traditional practices and beliefs across the different parts of Ethiopia. Shilshalo, which is yet little known about, is one of these practices existing in Argoba, a community in Amhara National Regional State of Ethiopia. This study was conducted to explore the various features ass...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-018-0179-x
更新日期:2018-11-20 00:00:00
abstract:BACKGROUND:A traditional pathway for developing new health products begins with public research institutes generating new knowledge, and ends with the private sector translating this knowledge into new ventures. But while public research institutes are key drivers of basic research in sub-Saharan Africa, the private se...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-10-S1-S10
更新日期:2010-12-13 00:00:00
abstract:BACKGROUND:Vietnam is shifting toward integrating HIV services into the public health system using social health insurance (SHI), and the HIV service delivery system is becoming decentralized. The study aim was to investigate current SHI coverage and patients' perspectives on this transition. METHODS:A survey of 1348 ...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-019-0221-7
更新日期:2020-01-10 00:00:00
abstract:BACKGROUND:Albinism is an inherited condition with a relatively high prevalence in populations throughout sub-Saharan Africa. People with oculocutaneous albinism have little or no pigment in their hair, skin and eyes; thus they are visually impaired and extremely sensitive to the damaging effect of the sun on their ski...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-018-0144-8
更新日期:2018-01-12 00:00:00
abstract:BACKGROUND:To determine whether training of providers participating in franchise clinic networks is associated with increased Family Planning service use among low-income urban families in Pakistan. METHODS:The study uses 2001 survey data consisting of interviews with 1113 clinical and non-clinical providers working i...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-10-26
更新日期:2010-11-09 00:00:00
abstract:UNLABELLED: BACKGROUND:While there are biomedical drugs for managing diabetes mellitus, some patients with diabetes use traditional medicine. The aim of the study was to explore why patients with diabetes use traditional medicine for the treatment of diabetes. METHODS:The study was conducted in Iganga and Bugiri dist...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-13-1
更新日期:2013-01-02 00:00:00
abstract:BACKGROUND:Worldwide, thousands of children are acting in different roles in armed groups. Whereas human rights activism and humanitarian imperatives tend to emphasize the image of child soldiers as incapable victims of adults' abusive compulsion, this image does not fully correspond with prevailing pedagogical and jur...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-015-0068-5
更新日期:2015-10-14 00:00:00
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journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-015-0045-z
更新日期:2015-04-03 00:00:00
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journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-11-S1-S13
更新日期:2011-03-09 00:00:00
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journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-13-9
更新日期:2013-01-29 00:00:00
abstract:BACKGROUND:The rights of women and people living with HIV (PLHIV) are protected under South African law, yet there is a gap in the application of these laws. While there are numerous systemic and social barriers to women's and PLHIV's exercise of their legal rights and rights to access social services, there has been l...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/s12914-016-0077-z
更新日期:2016-01-22 00:00:00
abstract::Vaccines have made a major contribution to public health, including the eradication of one deadly disease, small pox, and the near eradication of another, poliomyelitis.Through the introduction of new vaccines, such as those against rotavirus and pneumococcal diseases, and with further improvements in coverage, vaccin...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-9-S1-S2
更新日期:2009-10-14 00:00:00
abstract:BACKGROUND:An estimated 863 million people-a third of the world's urban population-live in slums, yet there is little information on the disease burden in these settings, particularly regarding chronic preventable diseases. METHODS:From March to May 2012, we conducted a cluster randomized survey to estimate the preval...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-14-19
更新日期:2014-05-21 00:00:00
abstract:BACKGROUND:The prevalence of Coronary Atherosclerotic Heart Disease (CASHD) is increasing in India. Several modifiable risk factors contribute directly to this disease burden. Public knowledge of such risk factors among the urban Indian population is largely unknown. This investigation attempts to quantify knowledge of...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-9-2
更新日期:2009-02-04 00:00:00
abstract:UNLABELLED: BACKGROUND:Given that many low income countries are heavily reliant on external assistance to fund their health sectors the acceptance of obligations of international assistance and cooperation with regard to the right to health (global health obligations) is insufficiently understood and studied by intern...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-12-31
更新日期:2012-11-15 00:00:00
abstract::The current political crisis, conflicts and riots in many Middle Eastern and African countries have led to massive migration waves towards Europe. European countries, receiving these migratory waves as first port of entry (POE) over the past few years, were confronted with several challenges as a result of the sheer v...
journal_title:BMC international health and human rights
pub_type: 信件
doi:10.1186/s12914-018-0150-x
更新日期:2018-02-08 00:00:00
abstract::BACKGROUND: Maternal, perinatal and neonatal mortality rates remain high in rural areas of developing countries. Most deliveries take place at home and care-seeking behaviour is often delayed. We report on a combined quantitative and qualitative study of care seeking obstacles and practices relating to perinatal illne...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-3-3
更新日期:2003-08-21 00:00:00
abstract:BACKGROUND:Despite a substantial decrease in child mortality in Ethiopia over the past decade, neonatal mortality remains unchanged (37/1000 live-births). This paper describes a qualitative study on beliefs and practices on immediate newborn and postnatal care in four rural communities of Ethiopia conducted to inform d...
journal_title:BMC international health and human rights
pub_type: 杂志文章
doi:10.1186/1472-698X-14-17
更新日期:2014-05-19 00:00:00