Abstract:
:Environmental conditions and xenobiotic exposure can be sources of stress to living organisms. Biological markers are measurable indicator of changes which may happen at any biological level and which can be considered an early warning signal of some biological or environmental state or condition. A structured field study was undertaken to investigate the relationship between three biomarker assays and the spatial and temporal variation of each biomarker in samples of Mytilus edulis. The three biomarkers were the neutral red retention assay, micronucleus assay and comet assay, which indicate damage at different cellular/molecular levels. Three sites in Poole Harbour, an area on the South coast of the UK were sampled on six separate occasions at least three weeks apart. The results for the comet assay showed a significant difference between sites and between sampling dates whereas the results for the other two assays did not show a significant difference for either factor. There was no significant correlation between the results of any pair of the three biomarkers. The results of the micronucleus assay showed a significant correlation with water temperature. This temperature effect, as well as induced repair, may contribute to explain the lack of a strict correspondence between pollution gradients and biomarkers responses.
journal_name
Mar Pollut Bulljournal_title
Marine pollution bulletinauthors
Strubbia S,Lyons BP,Lee RJdoi
10.1016/j.marpolbul.2018.09.055subject
Has Abstractpub_date
2019-01-01 00:00:00pages
322-327eissn
0025-326Xissn
1879-3363pii
S0025-326X(18)30697-0journal_volume
138pub_type
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