A Review of the Management of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.

Abstract:

BACKGROUND:Despite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysmal subarachnoid hemorrhage. OBJECTIVE:To define the scope of the problem and review key treatment strategies that have shaped the way CV is managed in the contemporary era. METHODS:A literature search was performed of CV management after aneurysmal subarachnoid hemorrhage. RESULTS:Recent advances in neuroimaging have led to improved detection of vasospasm, but established treatment guidelines including hemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centers. Experimental research in subarachnoid hemorrhage continues to identify novel targets for therapy. CONCLUSIONS:Proactive and preventive strategies such as oral nimodipine and endovascular rescue therapies can reduce the morbidity and mortality associated with CV.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Li K,Barras CD,Chandra RV,Kok HK,Maingard JT,Carter NS,Russell JH,Lai L,Brooks M,Asadi H

doi

10.1016/j.wneu.2019.03.083

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

513-527

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(19)30751-X

journal_volume

126

pub_type

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