Abstract：
OBJECTIVE:We retrospectively assessed the surgical outcomes of transitional meningioma (TM) in a relatively large series to evaluate the long-term outcomes and propose an appropriate treatment strategy for TM. METHODS:We included 298 patients who had undergone surgery from September 2011 to August 2013. The clinical characteristics, surgical record, and follow-up data for these patients were retrieved. RESULTS:The 298 enrolled patients included 213 women (71.5%). The mean and median age of the 298 patients was 50.7 ± 0.6 years and 52.0 years (range, 6.0-74.0), respectively. Radiologically, 144 tumors (48.3%) were located in the skull base. Gross total resection (GTR) was achieved in 266 patients (89.3%); 7 patients (2.6%) received adjuvant radiotherapy. After a median follow-up of 61.8 months, 23 patients (8.6%) had developed recurrence and 2 patients (0.8%) had died. The results from univariate analysis indicated that GTR was associated with better progression-free survival (hazard ratio, 0.165; 95% confidence interval, 0.071-0.382; P < 0.001).) Skull base tumors tended to predict for poor progression-free survival (hazard ratio, 2.169; 95% confidence interval, 0.919-5.118; P = 0.077). For the first tumor recurrence, 11 patients (47.8%) underwent gamma knife radiosurgery, and only 2 patients developed a second recurrence. CONCLUSION:The results from the present study have shown that GTR should be achieved during the first surgery for TM. Gamma knife radiosurgery might be an effective therapy for patients with tumor recurrence.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Ma XJ,Zhang GJ,Wang W,Li D,Wu Z,Zhang JTdoi
10.1016/j.wneu.2019.03.104subject
Has Abstractpub_date
2019-07-01 00:00:00pages
e280-e287eissn
1878-8750issn
1878-8769pii
S1878-8750(19)30772-7journal_volume
127pub_type
杂志文章abstract：BACKGROUND:Syringomyelia due to intracranial hypotension is rarely described. As a consequence, intracranial hypotension is less recognized as a potential cause of syringomyelia or mistaken with Chiari type 1 malformation. The pathogeny is poorly understood, and we lack diagnostic and therapeutic strategies for this pa...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2016-07-01 00:00:00
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journal_title：World neurosurgery
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.01.117
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2014-07-01 00:00:00
abstract：:Rare anomalous courses of vertebral arteries in the craniovertebral junction may compress the spinal cord causing myelopathy. We report here the severest form of this pathologic condition successfully treated with transposition of bilateral vertebral artery using Gore-Tex tapes. A 73-year-old man presented with progre...
journal_title：World neurosurgery
pub_type： 杂志文章
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abstract：BACKGROUND:Circumferential minimally invasive surgery (cMIS), as a technique for reducing the complications of adult spinal deformity surgery, is receiving considerable attention. Conventional cMIS is performed using intraoperative fluoroscopy. In this work, we describe a new cMIS technique without using C-arm fluorosc...
journal_title：World neurosurgery
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journal_title：World neurosurgery
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.169
更新日期：2018-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.11.109
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Pituitary apoplexy is a rare complication of the initial administration of leuprolide acetate. CASE DESCRIPTION:We present the case of a 63-year-old man who experienced headache, blurred vision, and loss of consciousness after initial leuprolide treatment for prostate carcinoma. Neuroimaging showed pituitar...
journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2016-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-05-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.165
更新日期：2018-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2013.02.009
更新日期：2014-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.026
更新日期：2018-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.235
更新日期：2018-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.062
更新日期：2017-05-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-08-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2017-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：World neurosurgery
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更新日期：2017-02-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:The anterior surgical approach to the cervical spine is known to be safe, and damage to the hypoglossal nerve and trigeminal pathway after the surgery is uncommon. However, once damage to those nerves occurs, the patient's quality of life can be severely impaired by discomfort and disability. CASE DESCRIPTI...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2020-04-01 00:00:00
