Cardiotoxicity of Immune Therapy.

Abstract:

:The advent of immunotherapy, particularly immune checkpoint inhibitors and chimeric antigen receptor T-cell therapy, has ushered in a promising new era of treatment of patients with a variety of malignancies who historically had a poor prognosis. However, these therapies are associated with potentially life-threatening cardiovascular adverse effects. As immunotherapy evolves to include a wider variety of malignancies, risk stratification, prompt recognition, and treatment of cardiotoxicity will become increasingly important and hence cardiologists will need to play a fundamental role in the comprehensive care of these patients. This article reviews cardiotoxicity associated with contemporary immunotherapy and discusses potential management strategies.

journal_name

Cardiol Clin

journal_title

Cardiology clinics

authors

Ganatra S,Parikh R,Neilan TG

doi

10.1016/j.ccl.2019.07.008

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

385-397

issue

4

eissn

0733-8651

issn

1558-2264

pii

S0733-8651(19)30057-8

journal_volume

37

pub_type

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