One System for All: Is Mass Spectrometry a Future Alternative for Conventional Antibiotic Susceptibility Testing?

abstract：:Helicobacter pylori does not encode the classical DsbA/DsbB oxidoreductases that are crucial for oxidative folding of extracytoplasmic proteins. Instead, this microorganism encodes an untypical two proteins playing a role in disulfide bond formation - periplasmic HP0231, which structure resembles that of EcDsbC/DsbG, ...

journal_title：Frontiers in microbiology

authors： Bocian-Ostrzycka KM,Łasica AM,Dunin-Horkawicz S,Grzeszczuk MJ,Drabik K,Dobosz AM,Godlewska R,Nowak E,Collet JF,Jagusztyn-Krynicka EK

更新日期：2015-10-08 00:00:00

abstract：:Cathelicidins (CATHs) are host defense peptides (HDPs) that play an important role in the innate immune response against infections. Although multiple functions of cathelicidins have been described, including direct antimicrobial activity and several immunomodulatory effects on the host, relatively little is known abo...

journal_title：Frontiers in microbiology

authors： Peng L,Du W,Balhuizen MD,Haagsman HP,de Haan CAM,Veldhuizen EJA

更新日期：2020-03-19 00:00:00

abstract：:Microorganisms are capable of synthesizing a plethora of secondary metabolites including the long-overlooked volatile organic compounds. Little knowledge has been accumulated regarding the regulation of the biosynthesis of such mVOCs. The emission of the unique compound sodorifen of Serratia plymuthica isolates was si...

journal_title：Frontiers in microbiology

authors： Magnus N,Weise T,Piechulla B

更新日期：2017-12-19 00:00:00

abstract：:Mining industries produce vast waste streams that pose severe environmental pollution challenge. Conventional techniques of treatment are usually inefficient and unsustainable. Biological technique employing the use of microorganisms is a competitive alternative to treat mine wastes and recover toxic heavy metals. Mic...

journal_title：Frontiers in microbiology

authors： Ayangbenro AS,Olanrewaju OS,Babalola OO

更新日期：2018-08-22 00:00:00

abstract：:Gut microbiota plays a critical role in maintaining human intestinal homeostasis and host health. Bacterial extracellular vesicles are key players in bacteria-host communication, as they allow delivery of effector molecules into the host cells. Outer membrane vesicles (OMVs) released by Gram-negative bacteria carry ma...

journal_title：Frontiers in microbiology

authors： Cañas MA,Fábrega MJ,Giménez R,Badia J,Baldomà L

更新日期：2018-03-20 00:00:00

abstract：:Flow cytometric analysis is a reliable and convenient method for investigating molecules at the single cell level. Previously, recombinant human immunodeficiency virus type 1 (HIV-1) strains were constructed that express a fluorescent reporter, either enhanced green fluorescent protein, or DsRed, which allow the monit...

journal_title：Frontiers in microbiology

authors： Terahara K,Yamamoto T,Mitsuki YY,Shibusawa K,Ishige M,Mizukoshi F,Kobayashi K,Tsunetsugu-Yokota Y

更新日期：2012-01-10 00:00:00

abstract：:Active volcanoes in Antarctica contrast with their predominantly cold surroundings, resulting in environmental conditions capable of selecting for versatile and extremely diverse microbial communities. This is especially true on Deception Island, where geothermal, marine, and polar environments combine to create an ex...

journal_title：Frontiers in microbiology

authors： Bendia AG,Signori CN,Franco DC,Duarte RTD,Bohannan BJM,Pellizari VH

更新日期：2018-05-07 00:00:00

abstract：:Our understanding of microbial natural environments combines in situ experimentation with studies of specific interactions in laboratory-based setups. The purpose of this work was to develop, build and demonstrate the use of a microbial culture chamber enabling both in situ and laboratory-based studies. The design use...

journal_title：Frontiers in microbiology

authors： Thøgersen MS,Melchiorsen J,Ingham C,Gram L

更新日期：2018-07-30 00:00:00

abstract：:In the present study, the mitogenome of Tuber calosporum was assembled and analyzed. The mitogenome of T. calosporum comprises 15 conserved protein-coding genes, two rRNA genes, and 14 tRNAs, with a total size of 287,403 bp. Fifty-eight introns with 170 intronic open reading frames were detected in the T. calosporum m...

journal_title：Frontiers in microbiology

authors： Li X,Li L,Bao Z,Tu W,He X,Zhang B,Ye L,Wang X,Li Q

更新日期：2020-12-09 00:00:00

abstract：:Thawing of permafrost soils is expected to stimulate microbial decomposition and respiration of sequestered carbon. This could, in turn, increase atmospheric concentrations of greenhouse gasses, such as carbon dioxide and methane, and create a positive feedback to climate warming. Recent metagenomic studies suggest th...

journal_title：Frontiers in microbiology

authors： Coolen MJ,Orsi WD

更新日期：2015-03-16 00:00:00

abstract：:Parys Mountain or Mynydd Parys (Isle of Anglesey, United Kingdom) is a mine-impacted environment, which accommodates a variety of acidophilic organisms. Our previous research of water and sediments from one of the surface acidic streams showed a high proportion of archaea in the total microbial community. To understan...

journal_title：Frontiers in microbiology

authors： Distaso MA,Bargiela R,Brailsford FL,Williams GB,Wright S,Lunev EA,Toshchakov SV,Yakimov MM,Jones DL,Golyshin PN,Golyshina OV

更新日期：2020-11-17 00:00:00

abstract：:Milk spoilage is caused by the presence of proteolytic enzymes produced by Pseudomonas spp. during storage at low temperatures. The aim of this study was to identify Pseudomonas spp. in raw milk and investigate their associated proteolytic properties at low temperatures. Raw milk samples (n = 87) were collected from 8...

journal_title：Frontiers in microbiology

authors： Meng L,Zhang Y,Liu H,Zhao S,Wang J,Zheng N

更新日期：2017-11-08 00:00:00

abstract：:Viruses and plasmids can introduce novel DNA into bacterial cells, thereby creating an opportunity for genome expansion; conversely, CRISPR, the prokaryotic adaptive immune system, which targets and eliminates foreign DNAs, may impair genome expansions. Recent studies presented conflicting results over the impact of C...

journal_title：Frontiers in microbiology

authors： Gao NL,Chen J,Wang T,Lercher MJ,Chen WH

更新日期：2019-10-16 00:00:00

abstract：:IncI-complex plasmids can be divided into seven subgroups IncI1, IncI2, IncIγ, IncB/O, IncK1, IncK2, and IncZ. In this study, a replicon-based scheme was proposed for typing IncI-complex plasmids into four separately clustering subgroups IncI2, IncI1/B/O, IncIγ/K1 and IncK2/Z, the last three of which were combined fro...

journal_title：Frontiers in microbiology

authors： Zhang D,Zhao Y,Feng J,Hu L,Jiang X,Zhan Z,Yang H,Yang W,Gao B,Wang J,Li J,Yin Z,Zhou D

更新日期：2019-01-29 00:00:00

abstract：:Climate change is accelerating the spread of plants and their associated species to new ranges. The differences in range shift capacity of the various types of species may disrupt long-term co-evolved relationships especially those belowground, however, this may be less so for seed-borne endophytic microbes. We collec...

journal_title：Frontiers in microbiology

authors： Geisen S,Kostenko O,Cnossen MC,Ten Hooven FC,Vreš B,van der Putten WH

更新日期：2017-08-29 00:00:00

abstract：:In Agrobacterium-mediated transformation (AMT) of plants, a single-strand (ss) T-DNA covalently linked with a VirD2 protein moves through a bacterial type IV secretion channel called VirB/D4. This transport system originates from conjugal plasmid transfer systems of bacteria. The relaxase VirD2 and its equivalent prot...

journal_title：Frontiers in microbiology

authors： Ohmine Y,Kiyokawa K,Yunoki K,Yamamoto S,Moriguchi K,Suzuki K

更新日期：2018-05-28 00:00:00

abstract：:Multiple carlaviruses infect various ornamental plants, often having limited host ranges and causing minor symptoms, yet often reducing yield or quality. In this study we have identified a mixed infection of butterbur mosaic virus (ButMV) and helenium virus S (HelVS) from a plant of veronica (Veronica sp.) showing fol...

journal_title：Frontiers in microbiology

authors： Hammond J,Reinsel M,Grinstead S,Lockhart B,Jordan R,Mollov D

更新日期：2020-12-21 00:00:00

abstract：:Cyanobacteria are major primary producers in the polar and alpine regions contributing significantly to nitrogen and carbon cycles in the cryosphere. Recent advancements in environmental sequencing techniques have revealed great molecular diversity of microorganisms in cold environments. However, there are no comprehe...

journal_title：Frontiers in microbiology

authors： Chrismas NA,Anesio AM,Sánchez-Baracaldo P

更新日期：2015-10-13 00:00:00

abstract：:Emerging evidence suggests that antibodies against merozoite proteins involved in Plasmodium falciparum invasion into the red blood cell (RBC) play an important role in clinical immunity to malaria. The protein family of parasite antigens known as P. falciparum reticulocyte binding protein-like homolog (PfRh) is requi...

journal_title：Frontiers in microbiology

authors： Chiu CY,Healer J,Thompson JK,Chen L,Kaul A,Savergave L,Raghuwanshi A,Li Wai Suen CS,Siba PM,Schofield L,Mueller I,Cowman AF,Hansen DS

更新日期：2014-06-30 00:00:00

abstract：:This study aimed to investigate antimicrobial resistance and molecular epidemiology of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli) isolated from outpatients in town hospitals of Shandong province, China. Antimicrobial susceptibility of ESBL-producing E. coli was tested using the disk diff...

journal_title：Frontiers in microbiology

authors： Miao Z,Li S,Wang L,Song W,Zhou Y

更新日期：2017-01-24 00:00:00

abstract：:The incidence of non-alcoholic fatty liver disease (NAFLD) is rising annually, and emerging evidence suggests that the gut bacteria plays a causal role in NAFLD. Naringin, a natural flavanone enriched in citrus fruits, is reported to reduce hepatic lipid accumulation, but to date, no investigations have examined wheth...

journal_title：Frontiers in microbiology

authors： Mu H,Zhou Q,Yang R,Zeng J,Li X,Zhang R,Tang W,Li H,Wang S,Shen T,Huang X,Dou L,Dong J

更新日期：2020-11-13 00:00:00

abstract：:Soil microbial diversity is huge and a few grams of soil contain more bacterial taxa than there are bird species on Earth. This high diversity often makes predicting the responses of soil bacteria to environmental change intractable and restricts our capacity to predict the responses of soil functions to global change...

journal_title：Frontiers in microbiology

authors： Le Roux X,Bouskill NJ,Niboyet A,Barthes L,Dijkstra P,Field CB,Hungate BA,Lerondelle C,Pommier T,Tang J,Terada A,Tourna M,Poly F

更新日期：2016-05-17 00:00:00

abstract：:Probiotic bacteria are recognized for their health-promoting properties, including maintenance of gut epithelial integrity and host immune system homeostasis. Taking into account the beneficial health-promoting effects of GABA, the presence of the gadB gene, encoding glutamate decarboxylase that converts L-glutamate t...

journal_title：Frontiers in microbiology

authors： Sokovic Bajic S,Djokic J,Dinic M,Veljovic K,Golic N,Mihajlovic S,Tolinacki M

更新日期：2019-03-18 00:00:00

abstract：:We characterized the mechanism of fluoroquinolone-resistance in two isolates of Streptococcus pseudopneumoniae having fluoroquinolone-efflux as unique mechanism of resistance. Whole genome sequencing and genetic transformation experiments were performed together with phenotypic determinations of the efflux mechanism. ...

journal_title：Frontiers in microbiology

authors： Alvarado M,Martín-Galiano AJ,Ferrándiz MJ,Zaballos Á,de la Campa AG

更新日期：2017-10-26 00:00:00

abstract：:Formate dehydrogenase H (FDH-H) and [NiFe]-hydrogenase 3 (Hyd-3) form the catalytic components of the hydrogen-producing formate hydrogenlyase (FHL) complex, which disproportionates formate to H2 and CO2 during mixed acid fermentation in enterobacteria. FHL comprises minimally seven proteins and little is understood a...

journal_title：Frontiers in microbiology

authors： Pinske C

更新日期：2018-06-11 00:00:00

abstract：:Pathogens have evolved mechanisms to modulate host cell functions and avoid recognition and destruction by the host damage response. For many years, researchers have focused on proteins as the main effectors used by pathogens to hijack host cell pathways, but only recently with the development of deep RNA sequencing t...

journal_title：Frontiers in microbiology

authors： Bayer-Santos E,Marini MM,da Silveira JF

更新日期：2017-03-21 00:00:00

abstract：:Tuberculosis (TB) disease is an international health concern caused by the bacteria Mycobacterium tuberculosis (Mtb). Evolution of multi-drug-resistant strains may cause bacterial persistence, rendering existing antibiotics ineffective. Hence, development of new or repurposing of currently approved drugs to fight Mtb ...

journal_title：Frontiers in microbiology

authors： Naicker N,Sigal A,Naidoo K

更新日期：2020-04-29 00:00:00

abstract：:The crosstalk between the gut microbiota and immune state of the host is an essential focus in academia and clinics. To explore the dynamic role of the microbiota in response to immune deficiency, we comprehensively assessed the microbiome of 90 mouse fecal samples, across three time points including two immunodeficie...

journal_title：Frontiers in microbiology

authors： Zheng S,Zhao T,Yuan S,Yang L,Ding J,Cui L,Xu M

更新日期：2019-11-01 00:00:00

abstract：:Composed of trillions of individual microbes, the human gut microbiota has adapted to the uniquely diverse environments found in the human intestine. Quickly responding to the variances in the ingested food, the microbiota interacts with the host via reciprocal biochemical signaling to coordinate the exchange of nutri...

journal_title：Frontiers in microbiology

authors： Selber-Hnatiw S,Rukundo B,Ahmadi M,Akoubi H,Al-Bizri H,Aliu AF,Ambeaghen TU,Avetisyan L,Bahar I,Baird A,Begum F,Ben Soussan H,Blondeau-Éthier V,Bordaries R,Bramwell H,Briggs A,Bui R,Carnevale M,Chancharoen M,Chevass

更新日期：2017-07-17 00:00:00

abstract：:The ability of human enteric pathogens to colonize plants and use them as alternate hosts is now well established. Salmonella, similarly to phytobacteria, appears to be capable of producing the plant hormone auxin via an indole-3-pyruvate decarboxylase (IpdC), a key enzyme of the IPyA pathway. A deletion of the Salmon...

journal_title：Frontiers in microbiology

authors： Cox CE,Brandl MT,de Moraes MH,Gunasekera S,Teplitski M

更新日期：2018-01-12 00:00:00