High low-density lipoprotein cholesterol level is the independent risk factor of primary patency rate of arteriovenous fistula.

Abstract:

OBJECTIVES:An arteriovenous fistula is the first choice of vascular access in dialysis patients. However, the correlations between patient factors and the arteriovenous fistula patency rate remain unclear. Therefore, we examined the effect of dialysis patient factors on arteriovenous fistula patency rate. METHODS:This study included 101 patients who received maintenance dialysis and used arteriovenous fistula for vascular access at Atami Hospital, International University of Health and Welfare in July 2018. A retrospective review was performed from the time of arteriovenous fistula creation to July 2018, and the primary and secondary arteriovenous fistula patency rates were investigated. The patency rate was calculated using the Kaplan-Meier method, and risk factor analysis was performed using Cox proportional hazards regression analysis. RESULTS:The primary patency rate of arteriovenous fistula was 71.2% at one year and 43.0% at five years, and the secondary patency rate was 92.7% at one year and 79.8% at five years. In the multivariate analysis, high low-density lipoprotein cholesterol (LDL-C) level and a history of diabetes were considered significant risk factors (HR 1.023, p value <0.01 and HR 2.550, p value <0.01, respectively). A log rank test was conducted on the groups of patients with LDL <90 mg/dl and LDL ≥90 mg/dl, and the <90 mg/dl group resulted in a good primary patency rate (p value 0.0327). CONCLUSIONS:High LDL-C level was considered the independent risk factors of arteriovenous fistula primary patency rate.

journal_name

Vascular

journal_title

Vascular

authors

Yamazaki T,Shirai H,Yashima J,Tojimbara T

doi

10.1177/1708538120905486

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

430-435

issue

4

eissn

1708-5381

issn

1708-539X

journal_volume

28

pub_type

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