Prevalence of hyperhomocysteinemia in vascular disease: comparative study of thrombotic venous disease vis-à-vis occlusive arterial disease.

Abstract:

:Studies on hyperhomocysteinemia in vascular occlusive disease have included mostly patients with arterial occlusion. However, more recent studies have included cases of venous occlusive disease as well. Our present study is aimed at comparing the prevalence of hyperhomocysteinemia in venous occlusive disease vis-à-vis arterial occlusive disease in the North Indian urban population. Homocysteine was estimated by chemiluminescent immunoassay in 205 normal controls and 536 patients, 244 presenting with arterial occlusion and 292 with venous thrombotic disease. The mean homocysteine in patients with arterial occlusion was 21.79 +/- 0.09 micromol/L (mean +/- standard error of measurement), in patients with venous thrombosis was 25.53 +/- 0.1 micromol/L, and in controls was 11.33 +/- 0.18 micromol/L. The prevalence of hyperhomocysteinemia (> 15 micromol/L) was 56.38% in arterial occlusive disease and 54.64% in venous thrombosis. In patients with peripheral vascular occlusive disease, patients with deep venous thrombosis (DVT) had the highest mean homocysteine level (25.51 micromol/L), which was even higher (32.14 micromol/L) when associated with pulmonary embolism (PE). There is a high prevalence of hyperhomocysteinemia in arterial and venous occlusive disease. Hence, in all patients with vascular occlusive disease, hyperhomocysteinemia should be elucidated and treated. In addition, long-term follow-up is required to ascertain whether the reduction in homocysteine decreases the thrombotic events and whether homocysteine levels can actually be of prognostic or predictive value in cases of DVT with PE.

journal_name

Vascular

journal_title

Vascular

authors

Bhargava S,Parakh R,Manocha A,Ali A,Srivastava LM

doi

10.2310/6670.2007.00031

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

149-53

issue

3

eissn

1708-5381

issn

1708-539X

journal_volume

15

pub_type

杂志文章

相关文献

Vascular文献大全
  • Inflammatory carotid pseudotumor: case report and review of the literature.

    abstract::Inflammatory carotid pseudotumor is a rare differential of a unilateral neck swelling in the carotid triangle. A 48-year-old man presented with a firm non-tender gradually progressive left neck swelling for five months. Computed tomography angiogram revealed a mass encasing the common carotid. Patient underwent excisi...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.1177/1708538112474261

    authors: Sen I,Stephen E,Agarwal S,Chugh S,Walter N

    更新日期:2014-04-01 00:00:00

  • Use of proximal aortic cuffs as an adjunctive procedure during endovascular aortic aneurysm repair.

    abstract::The purpose of this study was to evaluate the incidence and durability of additional proximal cuffs during endovascular abdominal aortic aneurysm repair (EVAR). A retrospective review of 90 EVAR patients was conducted. Postoperative survival, proximal sealing zone-related complications, and secondary procedures were a...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1258/rsmvasc.13.1.16

    authors: Biebl M,Hakaim AG,Lau LL,Oldenburg WA,Klocker J,Neuhauser B,Paz-Fumagalli R,McKinney JM,Stockland A

    更新日期:2005-01-01 00:00:00

  • May-Thurner syndrome: case report and review of the literature involving modern endovascular therapy.

    abstract::May-Thurner syndrome is a rare clinical entity involving venous obstruction of the left lower extremity. Obstruction occurs secondary to compression of the left common iliac vein between the right common iliac artery and the underlying vertebral body. Current management largely involves endovascular therapy. A review ...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.2310/6670.2009.00027

    authors: Moudgill N,Hager E,Gonsalves C,Larson R,Lombardi J,DiMuzio P

    更新日期:2009-11-01 00:00:00

  • Transradial interventions in contemporary vascular surgery practice.

    abstract:OBJECTIVES:Upper extremity arterial access is often required for endovascular procedures, especially for antegrade access to the visceral aortic branches. Radial arterial access has been shown previously to have low complication rates, and patients tolerate the procedure well and are able to recover quickly. However, t...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538118797556

    authors: Stern JR,Elmously A,Smith MC,Connolly PH,Meltzer AJ,Schneider DB,Ellozy SH

    更新日期:2019-02-01 00:00:00

  • Perioperative baseline β-blockers: An independent protective factor for post-carotid endarterectomy hypertension.

    abstract:OBJECTIVE:Post-carotid endarterectomy hypertension is a well-recognized phenomenon closely related to surgical complications. This study aimed to determine whether different kinds of perioperative antihypertensive drugs had a protective effect on post-carotid endarterectomy hypertension and influence on intraoperative ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120946538

    authors: Teng L,Fang J,Zhang Y,Liu X,Qu C,Shen C

    更新日期:2020-08-09 00:00:00

  • Long-term outcomes and factors influencing late survival following elective abdominal aortic aneurysm repair: A 24-year experience.

    abstract:BACKGROUND:Abdominal aortic aneurysms can be either treated by an open abdominal aortic aneurysm repair or an endovascular repair. Comparing clinical predictors of outcomes and those which influence survival rates in the long term is important in determining the choice of treatment offered and the decision-making proce...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115586682

    authors: Khashram M,Jenkins JS,Jenkins J,Kruger AJ,Boyne NS,Foster WJ,Walker PJ

    更新日期:2016-04-01 00:00:00

  • A systematic review of isolated radial artery harvesting as a conduit for lower limb bypass grafting.

    abstract:BACKGROUND:Whilst autologous vein conduits have been heralded as the first-line approach for patients undergoing lower limb bypass grafting procedures, patients with peripheral arterial occlusive disease may have exhausted venous options given prior use for cardiac surgery, varicose vein surgery, or lower limb revascul...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538118802055

    authors: Wee I,Choong AM

    更新日期:2019-04-01 00:00:00

  • Early outcomes after left subclavian artery revascularisation in association with thoracic endovascular aortic repair.

    abstract::Approximately 40-50% of patients undergoing thoracic endovascular aortic repair require left subclavian artery coverage for adequate proximal landing zone. Many of these patients undergo left subclavian artery revascularisation. However, outcomes data for left subclavian artery revascularisation in the context of thor...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538116647631

    authors: Oladokun D,Patterson BO,Brownrigg JR,deBruin JL,Holt PJ,Loftus I,Thompson MM

    更新日期:2017-02-01 00:00:00

  • Morphologic predictors of aortic expansion in chronic type B aortic dissection.

    abstract:AIM:To identify morphologic factors affecting aortic expansion in patients with uncomplicated type B aortic dissections. METHODS:Computed tomography data of 24 patients (18 male; median age: 61 years), diagnosed with acute uncomplicated type B aortic dissections between 2002 and 2013, were retrospectively reviewed. Al...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115591941

    authors: Kotelis D,Grebe G,Kraus P,Müller-Eschner M,Bischoff M,von Tengg-Kobligk H,Böckler D

    更新日期:2016-04-01 00:00:00

  • Importance of gender-specific role models in vascular surgery.

    abstract::The percentage of female physicians selecting vascular surgery for residency and/or fellowship lags behind percentages in general surgery selections. A number of factors, such as mentorship, gender biases, lifestyle, and job characteristics, have been proposed as explanations for the lower percentage of applicants. Th...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2008.00024

    authors: Shortell CK,Cook C

    更新日期:2008-05-01 00:00:00

  • Immediate surgery for acute internal carotid artery dissection and thrombosis during filter deployment prior to stenting: a case report.

    abstract::Carotid artery stenting (CAS) is a validated option in the treatment of selected extracranial carotid artery stenosis. Carotid artery dissection during CAS is a rare but potentially devastating complication. We report a case of acute dissection and thrombosis of the left internal carotid artery during filter tip wire ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538113478774

    authors: Tolva V,Bertoni GB,Bianchi PG,Keller GC,Casana R

    更新日期:2013-08-01 00:00:00

  • Outcome of lower extremity revascularization for peripheral artery occlusive disease: is there a difference between men and women?

    abstract::The incidence of peripheral arterial occlusive disease (PAD) increases with age. Women represent a growing percentage of the elderly population who present with PAD. While speculation exists that gender affects outcome after revascularization procedures, the literature is confusing and often conflicting. This review c...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.1258/vasc.2010.ra0042

    authors: Seymour KA,Sadowitz B,Amankwah KS,Gahtan V

    更新日期:2011-04-01 00:00:00

  • Two-stage combined basilic-brachial vein transposition.

    abstract::In the present report, we describe a two-stage technique of combined basilic and brachial vein transposition. Our patient had a brachial-basilic vein fistula created, but during the second stage for the transposition, a low basilic-brachial vein confluence was found. Instead of abandoning the procedure, the brachial v...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2009.00008

    authors: Kakkos SK,Haddad GK

    更新日期:2009-03-01 00:00:00

  • The different scenarios of urgent carotid revascularization for crescendo and single transient ischemic attack.

    abstract:OBJECTIVE:Carotid stenosis with crescendo-transient-ischemic-attack (cTIA) requires a prompt intervention to reduce the stroke risk. Few data are reported in literature about cTIA suggesting a different perioperative risk compared with patients with single TIA (sTIA). This study aimed to compare the outcome of carotid ...

    journal_title:Vascular

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1708538118799225

    authors: Pini R,Faggioli G,Gargiulo M,Gallitto E,Cacioppa LM,Vacirca A,Pisano E,Pilato A,Stella A

    更新日期:2019-02-01 00:00:00

  • Clinical outcomes of extended endovascular recanalization of 16 consecutive Buerger's disease patients.

    abstract:OBJECTIVE:Buerger's disease is one of the worst diseases causing peripheral artery occlusions (especially lower extremity) with increased morbidity and mortality. Endovascular treatment of the diseased arteries gains preference over bypass surgery nowadays. Here, we aimed to present the clinical outcomes of 16 consecut...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538118805623

    authors: Kacmaz F,Kaya A,Keskin M,Keceoglu S,Algin IH,Yilmazkaya B,Ilkay E

    更新日期:2019-06-01 00:00:00

  • Endovascular aneurysm sealing as an alternative for the treatment of failed endovascular aneurysm repair.

    abstract:OBJECTIVE:The Nellix EndoVascular Aneurysm Sealing (EVAS) system has offered a novel approach in the treatment of abdominal aortic aneurysm (AAA). While it is currently indicated as a primary procedure in patients with infrarenal AAA with suitable anatomy according to the indications for use, a few studies aimed to add...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538119897525

    authors: Lareyre F,Mialhe C,Dommerc C,Mbeutcha A,Raffort J

    更新日期:2020-06-01 00:00:00

  • The relationship between plaque cap morphology and access technique in lower extremity chronic total occlusion.

    abstract:OBJECTIVES:To evaluate access success according to plaque cap morphology in subjects with lower limb chronic total occlusion. METHODS:A retrospective study was performed for a three-year period. Subjects with lower extremity chronic total occlusion (Rutherford category 3-6, ischaemia) were included in the study. Cap m...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538118809855

    authors: Turkyilmaz S,Kavala AA

    更新日期:2019-04-01 00:00:00

  • Mortality outcomes of ruptured abdominal aortic aneurysms and rural presentation.

    abstract:OBJECTIVES:Centralisation of vascular surgery services has coincided with a move towards endovascular repair of ruptured abdominal aortic aneurysms with the goal to improve patient outcomes. The aim of this study was to assess the effect of rural presentation and transfer times on survival from ruptured abdominal aorti...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115599315

    authors: Munday E,Walker S

    更新日期:2016-10-01 00:00:00

  • Secondary Relining With Focal Flaring of Novel-Generation Balloon-Expandable Covered Stents for Endovascular Treatment of Significant Diameter Mismatch in the Aorto-Iliac Territory.

    abstract:OBJECTIVES:The aim of this study was to report on the safety and feasibility of secondary relining with focal flaring of novel-generation balloon-expandable covered stents for endovascular treatment of significant diameter mismatch in the aorto-iliac territory. Significant diameter mismatch was defined as >20% differen...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120945056

    authors: D'Oria M,Griselli F,Mastrorilli D,Gorgatti F,Bassini S,Riccitelli F,Calvagna C,Zamolo F,Lepidi S

    更新日期:2020-07-29 00:00:00

  • Treatment of aortic graft infection by in situ reconstruction with Omniflow II biosynthetic prosthesis.

    abstract::Currently available conduits for in situ reconstruction after excision of infected aortic grafts have significant limitations. The Omniflow II vascular prosthesis is a biosynthetic graft associated with a low incidence of infection that has succesfully been used in the treatment of infected infrainguinal bypass. We re...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115621195

    authors: Krasznai AG,Snoeijs M,Siroen MP,Sigterman T,Korsten A,Moll FL,Bouwman LH

    更新日期:2016-12-01 00:00:00

  • American board of vascular surgery: the first 7 years.

    abstract::The American Board of Vascular Surgery (ABVS) was incorporated in 1996 with a vision of improved training standards and certification of vascular surgeons. At that time, 91% of those holding American Board of Surgery Certificates of Added Qualifications in Vascular Surgery supported the formation of the ABVS. Subseque...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.1258/rsmvasc.12.1.20

    authors: Stanley JC,Veith FJ

    更新日期:2004-01-01 00:00:00

  • The correlation of the platelet-to-lymphocyte ratio with the severity of stenosis and stroke in patients with carotid arterial disease.

    abstract::Objectives Platelet-to-lymphocyte ratio is a novel biomarker, recently shown to be correlated with atherosclerotic inflammation. This study investigated the role of platelet-to-lymphocyte ratio in patients with carotid artery stenosis and stroke. Methods Patients, who underwent carotid angiography with Multiple Detect...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538116673770

    authors: İdil Soylu A,Arıkan Cortcu S,Uzunkaya F,Atalay YO,Bekçi T,Güngör L,Belet Ü

    更新日期:2017-06-01 00:00:00

  • General outcomes and risk factors for minor and major amputations in Brazil.

    abstract::Objectives Major and minor amputations are associated with significant rates of mortality. However, little is known about the impact of unplanned redo-amputation during the same hospitalization on outcomes. The objectives of this study were to identify the risk factors associated with in-hospital mortality after both ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538117736677

    authors: Leite JO,Costa LO,Fonseca WM,Souza DU,Goncalves BC,Gomes GB,Cruz LA,Nister N Jr,Navarro TP,Bath J,Dardik A

    更新日期:2018-06-01 00:00:00

  • Dissection of left iliac artery during anterior lumbar interspace fusion: Report of a case.

    abstract::Vascular injury is an uncommon complication of spine surgery. Among the different approaches, anterior lumbar interbody fusion has increased potential for vascular injuries, since the great vessels and their branches overly the disc spaces to be operated on, and retraction of these vessels is necessary to gain adequat...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538114534235

    authors: Fischer UM,Davies MG,El Sayed H

    更新日期:2015-04-01 00:00:00

  • Use of the AngioSculpt scoring balloon for infrapopliteal lesions in patients with critical limb ischemia: 1-year outcome.

    abstract::The AngioSculpt Scoring Balloon Catheter (AngioScore, Inc., Fremont, CA) is composed of a semicompliant balloon encircled by three nitinol spiral struts providing targeted lesion scoring on balloon inflation. Between April 2005 and April 2006, procedural and follow-up data on 31 patients (mean age 76 years; 54.8% male...

    journal_title:Vascular

    pub_type: 杂志文章,多中心研究

    doi:10.2310/6670.2009.00001

    authors: Bosiers M,Deloose K,Cagiannos C,Verbist J,Peeters P

    更新日期:2009-01-01 00:00:00

  • Clinical outcomes from profundoplasty performed as a sole procedure for revascularization in critically ischaemic limbs.

    abstract:OBJECTIVES:The aim of this study is to investigate the durability and clinical efficacy of profundoplasty as a sole procedure in patients presenting with critical limb ischaemia associated with profunda femoral artery disease and superficial femoral artery occlusion. METHODS:Retrospective analysis of outcomes from all...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120963901

    authors: Elsharkawi M,Elkassaby M,McVeigh N,Dowdall J,Barry M,Sheehan S

    更新日期:2020-10-14 00:00:00

  • Surgical treatment of abdominal aortic aneurysms associated with horseshoe kidney.

    abstract::Abdominal aortic aneurysm surgery associated with a horseshoe kidney (HSK) is a serious technical challenge for the surgeon. We reviewed our experience with 127 patients electively operated on between 1990 and 2004 for abdominal aortic aneurysm. Pre- and perioperative medical, surgical, and radiologic data were retros...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2006.00002

    authors: Göksel O,Cinar B,Kömürcü G,Ahin S,Eren T

    更新日期:2006-01-01 00:00:00

  • A rare complication of radial artery catheterization.

    abstract::An arterial pseudoaneurysm is a cavity which does not consist of three layers of arterial wall and is generally seen at femoral and radial artery sites due to bone fractures, arterial injuries and iatrogenic reasons such as catheterization. The treatment choice may be either surgical or conservative. Patients with pse...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1258/vasc.2010.cr0238

    authors: Inan MB,Acikgoz B,Yazicioglu L,Kaya B,Ozyurda U

    更新日期:2011-06-01 00:00:00

  • Which type of conditioning method protects the spinal cord from the ischemia-reperfusion injury in 24 hours?

    abstract:OBJECTIVE:This study was designed to test the effects of different types of preconditioning and postconditioning methods on spinal cord protection following aortic clamping. METHODS:The animals (rabbits) were divided into sham-operated, ischemic preconditioning, remote ischemic preconditioning, simultaneous aortic and...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538114568702

    authors: Sapmaz A,Ulus AT,Turan NN,Kaymaz FF,Yazıcıoğlu H,Ersöz S,Simsek E,Köksoy C

    更新日期:2015-12-01 00:00:00

  • Association of statins with aortic, peripheral, and visceral artery aneurysm development.

    abstract::Objectives Prior studies examining the effects of statins on arterial aneurysm development and progression yielded conflicting results due to their smaller size and presence of residual confounders. The objective of this study is to examine the association of statins with risk of being diagnosed with aortic, periphera...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538116684942

    authors: Mansi IA,Frei CR,Halm EA,Mortensen EM

    更新日期:2017-08-01 00:00:00