Synthesis of folic acid conjugated photoluminescent carbon quantum dots with ultrahigh quantum yield for targeted cancer cell fluorescence imaging.

Abstract:

:Folic acid functionalized carbon quantum dots (FA-CQDs) with ultrahigh quantum yield (50 %) were synthesized by one-pot hydrothermal route using citric acid. The synthesized CQDs were characterized by fluorescence spectroscopy, transmission electron microscopy (TEM), dynamic light scattering (DLS) and X-ray diffraction. The cell viability of about 95 % and 97 % were obtained for MTT assay of the CQDs and FA-CQDs toward MCF-7 cells after 24 h of incubation respectively. The FA-CQDs were successfully applied for targeted imaging of ovarian cancer (type HeLa) and human breast adenocarcinoma (type MCF7) cells using fluorescence microscope.

authors

Saljoughi H,Khakbaz F,Mahani M

doi

10.1016/j.pdpdt.2020.101687

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

101687

eissn

1572-1000

issn

1873-1597

pii

S1572-1000(20)30040-5

journal_volume

30

pub_type

杂志文章
  • PDT with TOOKAD(®) studied in the chorioallantoic membrane of fertilized eggs.

    abstract:BACKGROUND:The potential application of TOOKAD(®)-PDT for the treatment of blood vessels was investigated. TOOKAD(®) (WST09), a novel palladium-bacteriopheophorbide absorbs light in the near IR with a high quantum yield of intersystem crossing. Our study assessed the efficacy of this drug in inducing vascular damage wi...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/S1572-1000(05)00006-2

    authors: Rück A,Böhmler A,Steiner R

    更新日期:2005-03-01 00:00:00

  • The effect of indocyanine green-based photodynamic therapy on healthy fibroblast and keratinocyte cells.

    abstract:BACKGROUND:Photodynamic therapy is a promising invention to treat infections and cancer where conventional treatments are insufficient and have many side effects. Photodynamic therapy is mainly emphasized as having minimal side effects on healthy cells during local applications, even so photosensitizer can accumulate i...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101891

    authors: Topaloğlu N,Kadıköylü G,Onak G,Karaman O

    更新日期:2020-09-01 00:00:00

  • Multimodal cancer cell therapy using Au@Fe2O3 core-shell nanoparticles in combination with photo-thermo-radiotherapy.

    abstract::In this study, gold coated iron oxide nanoparticle (Au@Fe2O3 NP) was synthesized in a core-shell structure. Photothermal and radiosensitization effects of Au@Fe2O3 NPs were investigated on KB human mouth epidermal carcinoma cell line. Cell death and apoptosis were measured to study the effects of nanoparticles in comb...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2018.08.003

    authors: Hosseini V,Mirrahimi M,Shakeri-Zadeh A,Koosha F,Ghalandari B,Maleki S,Komeili A,Kamrava SK

    更新日期:2018-12-01 00:00:00

  • Real-world experience with 5-aminolevulinic acid for the photodynamic diagnosis of bladder cancer: Diagnostic accuracy and safety.

    abstract:BACKGROUND:5-Aminolevulinic acid (ALA)-mediated photodynamic diagnosis (PDD) has recently been approved in Japan for the management of non-muscle invasive bladder cancer. As such, the current study aimed to investigate the real-world diagnostic accuracy and safety of ALA-PDD-assisted transurethral resection of bladder ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101999

    authors: Yamamoto S,Fukuhara H,Karashima T,Inoue K

    更新日期:2020-12-01 00:00:00

  • Photodynamic inactivation of methicillin-resistant Staphylococcus aureus on skin using a porphyrinic formulation.

    abstract::Staphylococcus aureus is responsible for skin and soft tissue infections. Having in mind increased antibiotic resistance, in this study the efficacy of antimicrobial photodynamic therapy (aPDT) with a porphyrinic formulation (FORM) as photosensitizer (PS) to photoinactivate methicillin-resistant Staphylococcus aureus ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101754

    authors: Braz M,Salvador D,Gomes ATPC,Mesquita MQ,Faustino MAF,Neves MGPMS,Almeida A

    更新日期:2020-06-01 00:00:00

  • Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm.

    abstract:BACKGROUND:An appropriate photosensitizer (PS) for photodynamic inactivation should have a pronounced antimicrobial efficacy but low dark toxicity. The aim of this study is to investigate the concentration-dependent antimicrobial efficacies of methylene blue (MB) and chlorin e6 (Ce6), against Streptococcus mutans biofi...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101817

    authors: Nie M,Deng DM,Wu Y,de Oliveira KT,Bagnato VS,Crielaard W,Rastelli ANS

    更新日期:2020-09-01 00:00:00

  • Application of 5-aminolevulinic acid photodynamic therapy for vaginal intraepithelial neoplasia, a report of six cases.

    abstract:BACKGROUND:Vaginal intraepithelial neoplasia (VAIN) has a high-risk for recurrence and may precede genital cancers, such as vaginal cancer and/or other invasive diseases. Human papillomavirus (HPV)-induced VAIN may occur after loop electrosurgical excision procedures (LEEPs) or panhysterectomy. 5-aminolevulinic acid (A...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101837

    authors: Cai H,Ma T,Che Y,Yan L,Ding Z,Sun H

    更新日期:2020-09-01 00:00:00

  • Photodiagnosis and treatment of condyloma acuminatum using 5-aminolevulinic acid and homemade devices.

    abstract:BACKGROUND:The objective of this study was to improve the feasibility of applying topic 5-aminolevulinic acid (ALA) in photodiagnosis (PD) and treatment of condyloma caused by human papillomavirus (HPV) using two homemade handheld devices and to discuss the photodynamic therapy (PDT) as a suitable alternative for each ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.pdpdt.2011.09.001

    authors: Inada NM,Costa MM,Guimarães OC,Ribeiro Eda S,Kurachi C,Quintana SM,Lombardi W,Bagnato VS

    更新日期:2012-03-01 00:00:00

  • Treatment of verrucous carcinoma in penis with topical aminolevulinic acid photodynamic therapy: An effective and safe treatment method.

    abstract:BACKGROUND:Verrucous carcinoma of the penis is a rare disease characterized by verrucous lesions. The traditional treatment methods for verrucous carcinoma result in loss of sexual function are not satisfactory. The purpose of this study was to evaluate the safety and effect of topical aminolevulinic acid photodynamic ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2018.08.015

    authors: He X,Zhang J,Tan L,Wang W,Song Y,Wang H,Zhang X,Kou H,Lu Y

    更新日期:2018-12-01 00:00:00

  • Fluorescence-guided surgical management of medication-related osteonecrosis of the jaws.

    abstract::Medication-related osteonecrosis of the jaw (MRONJ) results in progressive destruction of the jawbones, and advanced cases demand surgical intervention. The total removal of necrotic bone is required to prevent recurrence and infection. However, determining the limits between necrotic and healthy bone is a challenge. ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章,评审

    doi:10.1016/j.pdpdt.2020.102003

    authors: Tomo S,da Cruz TM,Figueira JA,Cunha JLS,Miyahara GI,Simonato LE

    更新日期:2020-12-01 00:00:00

  • Evaluation of changes in choroidal vascularity during acute anterior uveitis attack in patients with ankylosing spondylitis by using binarization of EDI-optical coherence tomography images.

    abstract:BACKGROUND:To evaluate the effect of the first acute anterior uveitis (AAU) attack on the choroid by using an image binarization tool on images from enhanced depth imaging (EDI)-optical coherence tomography (OCT) scans in patients with ankylosing spondylitis (AS). METHODS:In this study, three groups were formed: uveit...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101778

    authors: Balci S,Turan-Vural E

    更新日期:2020-09-01 00:00:00

  • Red fluorescence of plaque in the dentition-a comparison of Quantitative Light-induced Fluorescence-Digital (QLF-D) images and conventional images of disclosed plaque.

    abstract:BACKGROUND:Quantitative Light-induced Fluorescence-Digital (QLF-D) detects red fluorescence of plaque, but is almost solely used on labial anterior tooth surfaces. As distribution and formation of plaque varies distinctly within the dentition, our aim was to investigate, how red fluorescing plaque is related to disclos...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.102063

    authors: Ganss C,Glanz A,Glanz T,Schlueter N,Ruf S

    更新日期:2020-12-01 00:00:00

  • The assessment of different bleaching agents' efficiency on discoloured teeth using image-processing methods.

    abstract:BACKGROUND:Although triple antibiotic paste (TAP) has been successfully used as an intracanal medicament for regenerative endodontic treatments, TAP has also been shown to cause discolouration. The aim of this study is to investigate the efficacy of different bleaching agents to bleach teeth discoloured from TAP. METH...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101901

    authors: Ozkocak I,Hekim M,Gokturk H,Adem K,Comert O

    更新日期:2020-09-01 00:00:00

  • In vitro light distributions from intracranial PDT balloons.

    abstract:BACKGROUND:Optical fibres can be placed in balloons to deliver light for intracranial photodynamic therapies. METHOD:A series of fibres, with either cleaved ends or terminating in cylindrical diffusers, housed in two different balloons, containing various solutions were investigated. The aim of the experiments perform...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2007.06.003

    authors: Moseley H,Mclean C,Hockaday S,Eljamel S

    更新日期:2007-09-01 00:00:00

  • Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial").

    abstract:INTRODUCTION:Conventional photodynamic therapy (cPDT) is considered a very effective treatment of actinic keratosis (AK) lesions. However, its use is limited by the fact that this procedure could be very painful. The use of topical anesthetics such as tetracaine or lignocaine/prilocaine has shown disappointing results ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101758

    authors: Brumana MB,Milani M,Puviani M

    更新日期:2020-06-01 00:00:00

  • Raman spectroscopy combined with multiple algorithms for analysis and rapid screening of chronic renal failure.

    abstract::Chronic renal failure (CRF) is a symptom of kidney damage in the terminal stages. If a patient is not treated, then CRF will progress to uremia, which greatly reduces the lifespan of the patient. However, current screening strategies, including routine urine tests and medical imaging investigations, have poor sensitiv...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2020.101792

    authors: Chen C,Yang L,Li H,Chen F,Chen C,Gao R,Lv XY,Tang J

    更新日期:2020-06-01 00:00:00

  • Clinical study on clinical operation and post-treatment reactions of HMME-PDT in treatment of PWS.

    abstract:OBJECTIVE:To analyze the clinical efficacy of hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) in treating port-wine stains (PWS), and its clinical operation skills and operation essentials. METHOD:A total of 16 cases of PWS with negative HMME skin test results were included in this study. Their treate...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章,评审

    doi:10.1016/j.pdpdt.2017.09.013

    authors: Zhang Y,Zou X,Chen H,Yang Y,Lin H,Guo X

    更新日期:2017-12-01 00:00:00

  • Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of photoaging.

    abstract:OBJECTIVE:The aim of this pilot study was to compare the efficacy of ALA-PDT and red light alone in the treatment of photoaging. METHODS:A total of 14 adults with photoaging skin were recruited. ALA-PDT or red light alone was applied to the forearm extensor. Before and after treatment, the treated sites were examined ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2014.02.007

    authors: Ji J,Zhang LL,Ding HL,Wang HW,Huang Z,Wang XX,Wang PR,Wang XL

    更新日期:2014-06-01 00:00:00

  • Enhancement of blood porphyrin emission intensity with aminolevulinic acid administration: a new concept for photodynamic diagnosis of early prostate cancer.

    abstract:BACKGROUND:The objective of this paper was to verify if the oral administration of δ-aminolevulinic acid (ALA) in animals with prostate tumor can increase the sensitivity of cancer diagnosis by protoporphyrin IX blood autofluorescence. In this study, the autofluorescence of blood porphyrin was analyzed using fluorescen...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2010.12.006

    authors: Silva FR,Bellini MH,Nabeshima CT,Schor N,Vieira ND Jr,Courrol LC

    更新日期:2011-03-01 00:00:00

  • Long-term Improvement on Photoaging After ALA Photodynamic Therapy for Actinic Keratosis: A Retrospective Study.

    abstract:BACKGROUND:5-aminolevulinic acid photodynamic therapy (ALA-PDT) is not only the first-line treatment for actinic keratosis (AK), but also demonstrated to improve photoaging during AK field treatment. However, its long-term improvement effect on photoaging remains elusive. OBJECTIVE:To evaluate the long-term improvemen...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2021.102181

    authors: Zhang L,Zhao Z,Wang P,Zhang G,Wang B,Shi L,Liu X,Zhou Z,Wang X

    更新日期:2021-01-08 00:00:00

  • Optical biopsy using spectral camera in BCC and oral leukoplakia.

    abstract::Basal cell carcinoma is one of the most common neoplasmatic diseases of the skin. Oral leukoplakia is precancerous stage. Early diagnosis of both diseases gives very good treatment results. Fluorescence spectroscopy is a new modality of diagnostics using excitation of absorbed PPIX in tumor. Spectroscopy is an objecti...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2008.10.001

    authors: Sieron A,Gibinski P,Pustelny T,Kwiatek S,Opilski Z,Kawczyk-Krupka A,Woznica T,Maciak E,Kubica W,Urbanczyk M,Latos W

    更新日期:2008-12-01 00:00:00

  • The influence of photodynamic therapy on the immune response.

    abstract::Photodynamic therapy (PDT) is a clinically approved therapeutic modality used for the management of several types of tumors as well as non-malignant diseases. Most of the effects of this treatment regimen result from direct action of singlet oxygen and reactive oxygen species. However, accumulating evidence indicates ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/S1572-1000(05)00098-0

    authors: Nowis D,Stokłosa T,Legat M,Issat T,Jakóbisiak M,Gołąb J

    更新日期:2005-12-01 00:00:00

  • Validity and reliability of autofluorescence-based quantification method of dental plaque.

    abstract:BACKGROUND:The aim of this study was to evaluate validity and reliability of autofluorescence-based plaque quantification (APQ) method. METHODS:The facial surfaces of 600 sound anterior teeth of 50 subjects were examined. The subjects received dental plaque examination using Turesky modified Quigley Hein plaque index ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2015.10.003

    authors: Han SY,Kim BR,Ko HY,Kwon HK,Kim BI

    更新日期:2015-12-01 00:00:00

  • Improving the competency of dental hygiene students in detecting dental restorations using quantitative light-induced fluorescence technology.

    abstract:OBJECTIVES:The purpose of this study was to determine the usefulness of a quantitative light-induced fluorescence (QLF) technology in detecting dental restorations by comparing the detection ability of dental hygiene students between using conventional visual inspection alone and visual inspection combined with QLF tec...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pdpdt.2016.12.010

    authors: Oh HY,Jung HI,Lee JW,de Jong EJ,Kim BI

    更新日期:2017-03-01 00:00:00

  • PDT induced bystander effect on human xenografted colorectal tumors as evidenced by sodium MRI.

    abstract:BACKGROUND:Previous in vivo studies on photodynamic therapy (PDT)-treated, high cellular density tumors showed evidences of a bystander effect accompanying the therapy, cellular death continuing beyond the limits of the photochemical reactions in time and space. This process is generated by the initially damaged cells ...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2012.03.001

    authors: Poyer F,Thomas CD,Garcia G,Croisy A,Carrez D,Maillard P,Lupu M,Mispelter J

    更新日期:2012-12-01 00:00:00

  • Optical coherence tomography in the diagnosis of actinic keratosis-A systematic review.

    abstract:BACKGROUND:Optical coherence tomography (OCT) is a real-time non-invasive imaging tool, introduced in dermatology in the late 1990s. OCT uses near-infrared light impulses to produce images which can be displayed in cross-sectional and en-face mode. The technique has been used to image skin diseases especially non-melan...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章,评审

    doi:10.1016/j.pdpdt.2017.02.003

    authors: Friis KBE,Themstrup L,Jemec GBE

    更新日期:2017-06-01 00:00:00

  • Endoscopic photodynamic therapy for oesophageal disease.

    abstract::Photodynamic therapy is a very important technique for the eradication of widespread oesophageal mucosal disease which has the potential to degenerate to cancer. Patients unsuitable or unwilling to undergo radical therapy can be cured using photodynamic therapy. We predominantly treat patients with high-grade dysplasi...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2006.03.008

    authors: Barr H,Kendall C,Bazant-Hegemark F,Stone N

    更新日期:2006-06-01 00:00:00

  • Synthesis, spectral characterization, crystal structure, cytotoxicity and apoptosis-Inducing activity of two derivatives of 2-hydroxy-1,4-naphthaquinone.

    abstract::A phenaxazone compound [5H-Benzo[a]phenoxazin-5-one (BP)] along with an aminoquinone[2-[(o-hydroxyphenyl)amino]-1,4-naphthaquinone (HAN)] derivatives were synthesized from lawsone using ultrasound irradiation technique. The structure of the compounds were characterized by elemental analysis and various spectral studie...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2017.01.180

    authors: P R KR,Fernandez A,Laila SP,B A,C S S,V S V

    更新日期:2017-03-01 00:00:00

  • 5-aminolevulinic acid mediated photodynamic therapy inhibits survival activity and promotes apoptosis of A375 and A431 cells.

    abstract:OBJECTIVES:The purpose of this study was to investigate the effects of 5-aminolaevulinic acid mediated photodynamic therapy (ALA-PDT) on the survival activity and apoptosis of human melanoma cell line A375 and non-melanoma skin carcinoma cell line A431 cells. The mechanism for cellular apoptosis was explored. METHODS:...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2018.01.004

    authors: Cai J,Zheng Q,Huang H,Li B

    更新日期:2018-03-01 00:00:00

  • Photophysical properties and in vitro photocytotoxicity of disodium salt 2.4-di(alpha-methoxyethyl)-deuteroporphyrin-IX (Dimegine).

    abstract::Photophysical and in vitro photocytotoxicity studies were performed for the photosensitizer Dimegine, a disodium salt 2.4-di(alpha-methoxyethyl)-deuteroporphyrin-IX with very low systemic toxicity. The singlet oxygen and luminescence quantum yield were ΦΔ = 0,65 ± 0,06, and Φƒ=0,11 ± 0,01 respectively, and were indepe...

    journal_title:Photodiagnosis and photodynamic therapy

    pub_type: 杂志文章

    doi:10.1016/j.pdpdt.2018.11.006

    authors: Dadeko AV,Lilge L,Kaspler P,Murav'eva TD,Starodubtcev AM,Kiselev VM,Zarubaev VV,Ponomarev GV

    更新日期:2019-03-01 00:00:00