Abstract：
:A healthy gut is predominantly occupied by bacteria which play a vital role in nutrition and health. Any change in normal gut homeostasis imposes gut dysbiosis. So far, efforts have been made to mitigate the gastrointestinal symptoms using modern day probiotics. The majority of the probiotics strains used currently belong to the genera Lactobacillus, Clostridium, Bifidobacterium and Streptococcus. Recent advancements in culturomics by implementing newer techniques coupled with the use of gnotobiotic animal models provide a subtle ground to develop novel host specific probiotics therapies. In this review article, the recent advances in the development of microbe-based therapies which can now be implemented to treat a wide spectrum of diseases have been discussed. However, these probiotics are not classified as drugs and there is a lack of stringent law enforcement to protect the end users against the pseudo-probiotic products. While modern probiotics hold strong promise for the future, more rigorous regulations are needed to develop genuine probiotic products and characterize novel probiotics using the latest research and technology. This article also highlights the possibility of reducing antibiotic usage by utilizing probiotics developed using the latest concepts of syn and ecobiotics.
journal_name
Indian J Microbioljournal_title
Indian journal of microbiologyauthors
Kumar R,Sood U,Gupta V,Singh M,Scaria J,Lal Rdoi
10.1007/s12088-019-00808-ysubject
Has Abstractpub_date
2020-03-01 00:00:00pages
12-25issue
1eissn
0046-8991issn
0973-7715pii
808journal_volume
60pub_type
杂志文章,评审abstract：:The effect of crude extract (Ce), seed coating agent (SCA) and whole bacterial broth culture (WBC) of Lysobacter strains was evaluated against the causal agent of clubroot formation in Cruciferous vegetables. The ability of four Lysobacter strains (L. antibioticus 6-B-1, L. antibioticus 6-T-4, L. antibioticus 13-B-1 a...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-018-0716-2
更新日期：2018-09-01 00:00:00
abstract：:The gene coding for ferric enterobactin binding protein from E. coli O157:H7 was amplifi ed. This gene was cloned and expressed as C-terminal His (6)-tagged protein. The SDS-PAGE analysis of the total protein revealed only two distinct bands, with molecular masses of 31kDa and 34kDa. The Ni-NTA chromatography purifi e...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-009-0044-7
更新日期：2009-09-01 00:00:00
abstract：:Ergosterol, an important component of the fungal cell membrane, is not only essential for fungal growth and development but also very important for adaptation to stress in fungi. Ergosterol is also a direct precursor for steroid drugs. The biosynthesis of ergosterol can be divided into three modules: mevalonate, farne...
journal_title：Indian journal of microbiology
pub_type： 杂志文章,评审
doi：10.1007/s12088-017-0657-1
更新日期：2017-09-01 00:00:00
abstract：:Cell biomass and metal salt concentration have great influence on morphology of biosynthesized nanoparticle. The aim of present study was to evaluate the effect of varying cell density and gold salt concentrations on synthesis of nanoparticles and its morphology, which has not been studied in bacteria till now. When c...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-016-0598-0
更新日期：2016-12-01 00:00:00
abstract：:A keratinolytic bacterium Elizabethkingia meningoseptica KB042 was isolated from dropped off feathers. The bacterium showed 82.50 ± 0.3% feather degradation when grown on medium containing 10 g/l chicken feathers with initial pH 7.0 at 37°C, 150 rpm in 6 days. The pH of the medium was increased up to 10.02 ± 0.10 duri...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-010-0014-0
更新日期：2010-10-01 00:00:00
abstract：:As one of the most significant swine diseases, in recent years, swine influenza (SI) has had an immense impact on public health and has raised extensive public concerns in China. Swine are predisposed to both avian and human influenza virus infections, between that and/or swine influenza viruses, genetic reassortment ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章,评审
doi：10.1007/s12088-013-0419-7
更新日期：2014-03-01 00:00:00
abstract：:Trichophyton spp. is one of the main causative agents of dermatophytosis such as tinea ungium and tinea pedis. Resistance to antifungal drugs is a significant clinical problem in dermatophytosis. The main molecular mechanism of antifungal resistance to conventional therapy in dermatophytes is the expression of efflux ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-020-00895-2
更新日期：2020-12-01 00:00:00
abstract：:Rapid and more sensitive methods for the detection and quantification of viable Legionella cells have been developed. In this paper, a comparative analysis of environmental water samples using the ScanVIT-Legionella™ method and the traditional "gold standard" method of culturing is realised indicating the usefulness o...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-013-0363-6
更新日期：2013-06-01 00:00:00
abstract：:Scoparia dulcis of Scrophulariaceae is an annual herb distributed through out the tropics. Penicillium citrinum was obtained from apparently healthy roots, stem, leaves and fruits of this plant. Callus and multiple shoots produced during micropropagation from various explants were also symptomless but showed occurrenc...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-010-0065-2
更新日期：2010-10-01 00:00:00
abstract：:Phytoplasma, an emerging plant pathogen is an endocellular obligate parasite of plant phloem tissues with highly reduced genomes and low GC content. They contain a minimal set of genes essential for survival as an intracellular parasite. The role of G-Quadruplexes in pathogenicity has been reported in a variety of mic...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-019-00831-z
更新日期：2019-12-01 00:00:00
abstract：:Extracellular polymeric substances (EPS) of microbial origin are a complex mixture of biopolymers comprising polysaccharides, proteins, nucleic acids, uronic acids, humic substances, lipids, etc. Bacterial secretions, shedding of cell surface materials, cell lysates and adsorption of organic constituents from the envi...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-008-0006-5
更新日期：2008-03-01 00:00:00
abstract：:Thermophilic bacteria are actively prevalent in hot water springs. Their potential to grow and sustain at higher temperatures makes them exceptional compare to other microorganism. The present study was initiated to isolate, identify and determine the feasibility of extraction of copper using thermophilic heterotrophi...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-011-0073-x
更新日期：2011-10-01 00:00:00
abstract：:A marked reduction in uptake of α-santonin, accompanied by loss of ability of cells to transform the substrate, is observed on shocking Sphingomonas paucimobilis strain S ATCC 43388 cells by freeze - thaw method. The shock fluid shows a 26% quench in fluorescence at 350nm on incubation with the substrate. Addition of ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-007-0064-0
更新日期：2007-12-01 00:00:00
abstract：:The native population of phosphate solubilizing bacteria (PSB) was studied in the rhizosphere of chickpea, mustard and wheat grown in different regions of Haryana. A total of 193 PSB were isolated from 245 rhizospheric samples collected from south-west and north-east zones. The PSB count showed large variations (3-67 ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-009-0016-y
更新日期：2009-06-01 00:00:00
abstract：:Among the cultivated mushroom, the genus Pleurotus is the second largest produced worldwide and the most produced in Brazil. The application of agricultural by-products (wastes) as substrate supplement is an effective approach to generate quality food while promoting a circular economy in agriculture. The manuscript e...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-019-00805-1
更新日期：2019-09-01 00:00:00
abstract：:The biodiversity of epilithic cyanobacteria from one of the unexplored habitats of freshwater streams of Kakoijana reserve forest of Assam, India was estimated. This paper lists a total of 29 species representing 18 genera of 12 families and 4 orders as per recent system of classification. Morphological descriptions, ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-007-0043-5
更新日期：2007-09-01 00:00:00
abstract：:A Gram negative, yellow pigmented, rod shaped bacterium designated as RL(T) was isolated from a hot water spring (90-98 °C) located at Manikaran in Northern India. The isolate grows at 60-80 °C (optimum, 70 °C) and at pH 7.0-9.0 (optimum pH 7.2). Phylogenetic analysis of 16S rRNA gene sequences and levels of DNA-DNA r...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-015-0538-4
更新日期：2015-12-01 00:00:00
abstract：:Sulfate-reducing bacteria (SRB) were found to be capable of tolerating a certain amount of oxygen (O2), but how they affect oxygen reduction reaction (ORR) has not been clear. The present work investigated the impact of SRB on ORR in 3.5 wt% sodium chloride solution with the cyclic voltammetry method. The addition of ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-017-0667-z
更新日期：2017-09-01 00:00:00
abstract：:Diversity analysis of Clostridium botulinum strains is complicated by high microheterogeneity caused by the presence of 9-22 copies of rrs (16S rRNA gene). The need is to mine genetic markers to identify very closely related strains. Multiple alignments of the nucleotide sequences of the 212 rrs of 13 C. botulinum str...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-015-0514-z
更新日期：2015-06-01 00:00:00
abstract：:Attempts were made to optimize the cultural conditions for the production of L-asparaginase by Streptomyces albidoflavus under submerged fermentations. Enhanced level of L-asparaginase was found in culture medium supplemented with maltose as carbon source. Yeast extract (2%) was served as good nitrogen source for the ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-008-0018-1
更新日期：2008-09-01 00:00:00
abstract：:Bacillus subtilis XF-1 has been used as a biocontrol agent of clubroot disease of crucifers infected by Plasmodiophora brassicae, an obligate pathogen. In order to maximize the growth inhibition of the pathogen, random mutagenesis using N-methyl-N'-nitro-N-nitrosoguanidine was applied to strain XF-1. The efficacy of 2...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-014-0471-y
更新日期：2014-12-01 00:00:00
abstract：:Bacteria possessing multiple copies of 16S rRNA (rrs) gene demonstrate high intragenomic heterogeneity. It hinders clear distinction at species level and even leads to overestimation of the bacterial diversity. Fifty completely sequenced genomes belonging to 19 species of Lactobacillus species were found to possess 4-...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-016-0605-5
更新日期：2016-09-01 00:00:00
abstract：:The present study was conducted to develop and evaluate an experimental ISCOM-based infectious bursal disease (IBD) vaccine. The indigenous very virulent infectious bursal disease virus (vvIBDV) already attenuated and adapted to Vero cell line was used. After denaturation of viral proteins with sodium dodecyl sulphate...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-008-0048-8
更新日期：2008-09-01 00:00:00
abstract：:Reports in recent years indicate that the increasing emergence of resistance to drugs be using to TB treatment. The resistance to them severely affects to options for effective treatment. The emergence of multidrug-resistant tuberculosis has increased interest in understanding the mechanism of drug resistance in M. tu...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-015-0511-2
更新日期：2015-06-01 00:00:00
abstract：:The minD gene encoding an inhibitor cell division MinD homolog from Lactobacillus acidophilus VTCC-B-871 was cloned. We showed that there were 97 % homology between minD genes of L. acidophilus VTCC-B-871 and Lactobacillus rhamnosus GG and Lactobacillus rhamnosus Lc705. Based on the analysis of the DNA sequence data f...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-013-0384-1
更新日期：2013-12-01 00:00:00
abstract：:This study reports the identification of ionising radiation tolerant bacteria from a high elevation arid region of central Tibet. Nineteen isolates were isolated from soil exposed to ionising radiation at doses from 0 to 15 kGy. Isolates were phylogenetically characterised using 16S rRNA gene sequences. Most isolates ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-016-0604-6
更新日期：2016-12-01 00:00:00
abstract：:Terminalia chebula Retz. is a northern Indian plant species known for its anti-inflammatory and antimicrobial properties. T. chebula fruit powder was extracted with solvents of varying polarity and screened for bacterial growth inhibition by disc diffusion assay. The minimum inhibitory concentration (MIC) was quantifi...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-018-0754-9
更新日期：2018-12-01 00:00:00
abstract：:The enhancement of production of asperenone (Fig. 1), an inhibitor of lipoxygenase and human platelet aggregation from Aspergillus niger CFTRI 1105, was achieved by UV and nitrous acid mutagenesis. Nitrous acid mutants exhibited increased inhibitor production when compared with UV irradiated mutants. I N 41 a first-ge...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-008-0026-1
更新日期：2008-06-01 00:00:00
abstract：:Most pathogens in intestine are opportunist, called "opportunistic pathogens" that usually do not cause disease in a healthy host. Only when the host's resistance is lowered or the intestinal microecological balance is destroyed, the opportunistic pathogens are capable of causing disease. Here, two opportunistic patho...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-013-0394-z
更新日期：2013-12-01 00:00:00
abstract：:Decontamination of suspected packages, such as sealed envelopes, liquids and tools that are likely contaminated with biological agents is of great importance. In this study, we aimed to determine the gamma radiation dose required for the decontamination of paper, fabric and liquid materials without causing any damage ...
journal_title：Indian journal of microbiology
pub_type： 杂志文章
doi：10.1007/s12088-017-0691-z
更新日期：2018-03-01 00:00:00
