Polydatin Inhibits Mitochondrial Dysfunction in the Renal Tubular Epithelial Cells of a Rat Model of Sepsis-Induced Acute Kidney Injury.

abstract：UNLABELLED:The most effective group of drugs for the treatment of severe pain is opioid analgesics. Their use, however, is limited by decreased effects in neuropathic and chronic pain as a result of increased pain and development of tolerance. Gabapentin (GBP) is effective in both experimental models of chronic pain an...

journal_title：Anesthesia and analgesia

authors： Eckhardt K,Ammon S,Hofmann U,Riebe A,Gugeler N,Mikus G

更新日期：2000-07-01 00:00:00

abstract：INTRODUCTION:The mechanisms by which mechanical ventilation (MV) can injure remote organs, such as the kidney, remain poorly understood. We hypothesized that upregulation of systemic inflammation, as reflected by plasma interleukin-6 (IL-6) levels, in response to a lung-injurious ventilatory strategy, ultimately result...

journal_title：Anesthesia and analgesia

authors： Kuiper JW,Versteilen AM,Niessen HW,Vaschetto RR,Sipkema P,Heijnen CJ,Groeneveld AB,Plötz FB

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Chemical pleurodesis causes severe pain, prompting physicians to perform thoracoscopic talc poudrage under general or neuroleptanalgesia. We describe a novel method for pain control in five patients with pneumothoraces and severe chronic obstructive pulmonary disease. METHODS:Patients were premedicated with...

journal_title：Anesthesia and analgesia

authors： Lee P,Colt HG

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this study was to determine whether injection rate affects the spread of hypobaric spinal anesthesia. Hypobaric spinal anesthesia was performed on 20 patients for total hip arthroplasty. Dural puncture was performed with a 22-gauge Whitacre needle. All patients received 10 mg of hypobaric tetracaine wit...

journal_title：Anesthesia and analgesia

authors： Atchison SR,Wedel DJ,Wilson PR

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:In cardiac surgery, pulmonary hypertension is an important prognostic factor for which several treatments have been suggested over time. In this systematic review and meta-analysis, we compared the efficacy of inhaled aerosolized vasodilators to intravenously administered agents and to placebo in the treatme...

journal_title：Anesthesia and analgesia

authors： Elmi-Sarabi M,Deschamps A,Delisle S,Ased H,Haddad F,Lamarche Y,Perrault LP,Lambert J,Turgeon AF,Denault AY

更新日期：2017-08-01 00:00:00

abstract：:Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injur...

journal_title：Anesthesia and analgesia

authors： van Caster P,Eiling S,Boekholt Y,Behmenburg F,Dorsch M,Heinen A,Hollmann MW,Huhn R

更新日期：2018-02-01 00:00:00

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：UNLABELLED:Clinical pathways are being introduced by hospitals to reduce costs and control unnecessary variation in care. We studied 766 inpatients to measure the impact of a perioperative clinical pathway for patients undergoing knee replacement surgery on hospital costs. One hundred twenty patients underwent knee rep...

journal_title：Anesthesia and analgesia

authors： Macario A,Horne M,Goodman S,Vitez T,Dexter F,Heinen R,Brown B

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

journal_title：Anesthesia and analgesia

authors： Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

更新日期：2017-03-01 00:00:00

abstract：UNLABELLED:In this prospective investigation, we evaluated the efficacy and accuracy of transcutaneous monitoring of CO2 (TC-CO2) in infants and children after cardiothoracic surgery. Cardiothoracic surgery patients whose ETCO2 and arterial CO2 values did not correlate (gradient > or = 5 mm Hg) during the first postope...

journal_title：Anesthesia and analgesia

authors： Tobias JD,Wilson WR Jr,Meyer DJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Frailty, a state of decreased physiological reserve, is strongly associated with perioperative mortality in older adults. However, the mechanism by which frailty is associated with mortality is not yet understood. Autonomic dysfunction in the form of decreased intraoperative hemodynamic variability has been ...

journal_title：Anesthesia and analgesia

authors： James LA,Levin MA,Lin HM,Deiner SG

更新日期：2019-06-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：UNLABELLED:Tropisetron is a 5-hydroxytryptamine subtype 3 receptor antagonist that is primarily used in the prevention of chemotherapy-induced nausea and vomiting. We evaluated the prophylactic effect of tropisetron on postoperative nausea and vomiting associated with epidural morphine. Dexamethasone and saline served ...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Tzeng JI,Ho ST,Chen JY,Chu CC,So EC

更新日期：2002-03-01 00:00:00

abstract：UNLABELLED:Several pharmacological interventions reduce perioperative stress hormone release during surgery under general anesthesia. Listening to music and therapeutic suggestions were also studied, but mostly in awake patients, and these have a positive effect on postoperative recovery and the need for analgesia. In ...

journal_title：Anesthesia and analgesia

authors： Migneault B,Girard F,Albert C,Chouinard P,Boudreault D,Provencher D,Todorov A,Ruel M,Girard DC

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Three cases of drug-induced liver injury (DILI) have been reported after desflurane anesthesia. However, no previous reports have detected serum autoantibodies such as that reported with DILI from halothane or isoflurane. METHODS AND RESULTS:We describe the first documentation of cytochrome P450 2E1 IgG4 au...

journal_title：Anesthesia and analgesia

authors： Anderson JS,Rose NR,Martin JL,Eger EI,Njoku DB

更新日期：2007-06-01 00:00:00

abstract：:This study was designed to evaluate the impact of routine end-tidal anesthetic gas monitoring on the intraoperative hemodynamic stability and early recovery profile in 253 consenting ASA physical status I-III patients undergoing elective otolaryngologic procedures with isoflurane or enflurane anesthesia. Patients were...

journal_title：Anesthesia and analgesia

authors： Wang J,Liu J,White PF,Klein KW,Browne RH

更新日期：1994-09-01 00:00:00

abstract：:Tracheal temperature--the temperature of the tracheal wall--is believed to reflect the core temperature. The trachea reacts quickly to temperature changes because it is surrounded by various large arteries and veins. Using the blood temperature from the cardiopulmonary bypass (CPB) and the jugular vein temperature as ...

journal_title：Anesthesia and analgesia

authors： Yamakage M,Kawana S,Watanabe H,Namiki A

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

journal_title：Anesthesia and analgesia

authors： Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

更新日期：2011-03-01 00:00:00

abstract：:The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership with the US Food and Drug Administration, convened a meeting of sedation e...

journal_title：Anesthesia and analgesia

authors： Williams MR,Ward DS,Carlson D,Cravero J,Dexter F,Lightdale JR,Mason KP,Miner J,Vargo JJ,Berkenbosch JW,Clark RM,Constant I,Dionne R,Dworkin RH,Gozal D,Grayzel D,Irwin MG,Lerman J,O'Connor RE,Pandharipande P,Rappap

更新日期：2017-03-01 00:00:00

abstract：:Although clonidine has been shown to increase the duration of local anesthetic action and prolong postoperative analgesia when included in single-injection nerve blocks, a controlled investigation of the efficacy of this practice to improve analgesia for continuous perineural local anesthetic infusion has not been rep...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Morey TE,Enneking FK

更新日期：2003-09-01 00:00:00

abstract：UNLABELLED:We evaluated the blood-sparing effects of intraoperative moderate acute normovolemic hemodilution (ANH) combined with intraoperative tranexamic acid treatment and shed blood reinfusion in patients undergoing off-pump coronary artery bypass (OPCAB). One-hundred consecutive OPCAB patients (baseline hematocrit ...

journal_title：Anesthesia and analgesia

authors： Casati V,Benussi S,Sandrelli L,Grasso MA,Spagnolo S,D'Angelo A

更新日期：2004-05-01 00:00:00

abstract：:The respiratory variations in the plethysmographic (PLET) waveform of the pulse oximeter during mechanical ventilation can be automatically quantified as the PLET variation index (PVI(®)). Like other dynamic variables, the PVI may provide useful information about fluid responsiveness but only when the patient is recei...

journal_title：Anesthesia and analgesia

authors： Perel A

更新日期：2014-12-01 00:00:00

abstract：:R-phenylisopropyl-adenosine, which has an affinity for the adenosine A1 receptor higher than that for the A2 receptor, and N-ethylcarboxamide-adenosine, which has near equal affinity for the A1 and A2 receptors, were injected intrathecally into rats to evaluate differences in antinociceptive effect and motor impairmen...

journal_title：Anesthesia and analgesia

authors： Karlsten R,Gordh T Jr,Hartvig P,Post C

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Inhalation agents are being used in place of intravenous agents to provide sedation in some intensive care units. We performed a systematic review and meta-analysis of prospective randomized controlled trials, which compared the use of volatile agents versus intravenous midazolam or propofol in critical care...

journal_title：Anesthesia and analgesia

authors： Jerath A,Panckhurst J,Parotto M,Lightfoot N,Wasowicz M,Ferguson ND,Steel A,Beattie WS

更新日期：2017-04-01 00:00:00

abstract：UNLABELLED:As medical costs continue to escalate, there is willingness to consider the role played by nontraditional factors in health. We investigated the usefulness of tape-recorded hypnosis instruction on perioperative outcome in surgical patients in a prospective, randomized, and partially blinded study. Sixty pati...

journal_title：Anesthesia and analgesia

authors： Ghoneim MM,Block RI,Sarasin DS,Davis CS,Marchman JN

更新日期：2000-01-01 00:00:00

abstract：:Outcomes after cardiac arrest remain poor more than a half a century after closed chest cardiopulmonary resuscitation (CPR) was first described. This review article is focused on recent insights into the physiology of blood flow to the heart and brain during CPR. Over the past 20 years, a greater understanding of hear...

journal_title：Anesthesia and analgesia

authors： Lurie KG,Nemergut EC,Yannopoulos D,Sweeney M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, a selective α2-adrenergic agonist currently approved for continuous intensive care unit sedation, is being widely evaluated for its role as a potential anesthetic. The closed-loop anesthesia delivery system (CLADS) is a method to automatically administer propofol total intravenous anesthesia...

journal_title：Anesthesia and analgesia

authors： Dutta A,Sethi N,Sood J,Panday BC,Gupta M,Choudhary P,Puri GD

更新日期：2019-07-01 00:00:00

abstract：:This study used the activated clotting time (ACT) to determine the clinical onset of four different doses of heparin after bolus injection into the central circulation. Ten consenting adults (Group A) undergoing coronary artery bypass grafting were given 350 U/kg of bovine lung heparin and had simultaneous duplicate a...

journal_title：Anesthesia and analgesia

authors： Heres EK,Speight K,Benckart D,Marquez J,Gravlee GP

更新日期：2001-06-01 00:00:00

abstract：:An early transesophageal echocardiography (TEE) study reported that there was high inter- and intraobserver variability in measurements of wall thickening (WT). This study reevaluated TEE for the measurement of WT in the transverse plane and, for the first time, evaluated it in the longitudinal plane. Ten patients wer...

journal_title：Anesthesia and analgesia

authors： Konstadt SN,Abrahams HP,Nejat M,Reich DL

更新日期：1994-04-01 00:00:00