The need for cost-effective choices to treat patients with bipolar 1 disorders including asenapine.

Abstract:

BACKGROUND:Bipolar 1 disorders (BPD) are a chronic disorder with prevalence rates of up to 2.6% of the adult population or higher and appreciable direct and indirect costs. As a result, these are a concern to health authorities especially given the low age of onset. Consequently, there is a need to treat BPD patients well and improve their quality-of-life. Pharmacotherapy includes mood stabilizers and atypical antipsychotics (AAPs). AAPs have different mechanisms of action and side-effects, so treatment needs to be tailored. Asenapine in clinical trials is as effective as olanzapine, with less metabolic side-effects. METHODS:Chitnis and colleagues assessed the cost-effectiveness of asenapine among patients in healthcare databases. RESULTS AND CONCLUSION:They showed in routine care that asenapine also reduces hospital and emergency room admissions, making it cost neutral in BPD, which is of interest to health authorities and clinicians.

journal_name

J Med Econ

authors

Godman B

doi

10.3111/13696998.2015.1073736

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

871-3

issue

11

eissn

1369-6998

issn

1941-837X

journal_volume

18

pub_type

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