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Origin of methicillin-resistant Staphylococcus aureus health care-associated infections: evaluation of the role of anterior nares.

Abstract：

:Methicillin-resistant Staphylococcus aureus (MRSA) health care-associated infections (HAIs) are a cause of extended hospitalizations and escalating health care costs. We typed 49 MRSA HAIs and their corresponding admission nasal MRSA isolates to determine strain-relatedness and better define the role of anterior nares in the causation of HAI and the value of decolonization. Based on repetitive extragenic palindromic sequencing polymerase chain reaction results, the majority of our patients possibly acquired MRSA HAI from nonnasal sources (36 out of 49; 74%). Among the remaining patients (13 out of 49; 26%) the nasal and clinical HAI isolates matched, indicating potential benefit of decolonization among this subsegment of patients. These findings may be relevant to institutions such as Veterans Health Administration hospitals that already have universal screening programs but are looking at ways to further reduce MRSA HAI incidence.

journal_name

Am J Infect Control

journal_title

American journal of infection control

authors

Jinadatha C,Hussain Z,Erickson TA,Villamaria FC,Copeland LA,Huber TW

doi

10.1016/j.ajic.2015.05.026

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

1125-7

issue

10

eissn

0196-6553

issn

1527-3296

pii

S0196-6553(15)00615-X

journal_volume

43

pub_type

杂志文章

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