Hidradenitis suppurativa and concomitant pyoderma gangrenosum treated With infliximab.

Abstract:

:Pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS) are rare chronic inflammatory dermatoses of unknown etiologies that often are refractory to conventional treatments. The therapeutic benefits of tumor necrosis factor a (TNF-α) inhibitors have been reported in patients with refractory PG or HS. The copresentation of these 2 diseases has previously been described in several cases in the literature and may present a therapeutic challenge. We present the case of a 51-year-old man who developed widespread inflammatory ulcers affecting approximately 50% of the body surface area and subsequent chronic debilitation from severe pain. He was ultimately diagnosed with concurrent PG and HS. Both diseases remitted in response to treatment with infliximab, which resulted in complete restoration of skin integrity and resolution of his chronic severe pain.

journal_name

Cutis

journal_title

Cutis

authors

Groleau PF,Grossberg AL,Gaspari AA

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

337-42

issue

6

eissn

0011-4162

issn

2326-6929

journal_volume

95

pub_type

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