Pasteurella multocida Pm0442 Affects Virulence Gene Expression and Targets TLR2 to Induce Inflammatory Responses.

abstract：:In vitro and in vivo research based on cell lines and animals are likely to be insufficient in elucidating authentic biological and physiological phenomena mimicking human systems, especially for generating pre-clinical data on targets and biomarkers. There is an obvious need for a model that can further bridge the ga...

journal_title：Frontiers in microbiology

authors： Tan KS,Yan Y,Koh WLH,Li L,Choi H,Tran T,Sugrue R,Wang Y,Chow VT

更新日期：2018-11-14 00:00:00

abstract：:Two-component regulatory systems (TCSSs) are key regulatory elements responsible for the adaptation of bacteria to environmental stresses. A classical TCSS is typically comprised of a sensory histidine kinase and a corresponding response regulator. Here, we used homologous recombination to construct a Mycobacterium sm...

journal_title：Frontiers in microbiology

authors： Dadura K,Płocińska R,Rumijowska-Galewicz A,Płociński P,Żaczek A,Dziadek B,Zaborowski A,Dziadek J

更新日期：2017-11-03 00:00:00

abstract：:Bacterial species differ greatly in the number and location of the rRNA operons which may be present in the bacterial chromosomes and plasmids. Most bacterial species contain more than one ribosomal RNA operon copy in their genomes, with some species containing up to 15 such copies. We review the number and location o...

journal_title：Frontiers in microbiology

authors： Espejo RT,Plaza N

更新日期：2018-06-08 00:00:00

abstract：:A core issue in microbial ecology is the need to elucidate the ecological processes and underlying mechanisms involved in microbial community assembly. However, the extent to which these mechanisms differ in importance based on traits of taxa with different niche breadth is poorly understood. Here, we used high-throug...

journal_title：Frontiers in microbiology

authors： Luo Z,Liu J,Zhao P,Jia T,Li C,Chai B

更新日期：2019-02-11 00:00:00

abstract：:Aquatic environments are reservoirs of the human pathogen Vibrio cholerae O1, which causes the acute diarrheal disease cholera. Upon low temperature or limited nutrient availability, the cells enter a viable but non-culturable (VBNC) state. Characteristic of this state are an altered morphology, low metabolic activity...

journal_title：Frontiers in microbiology

authors： Brenzinger S,van der Aart LT,van Wezel GP,Lacroix JM,Glatter T,Briegel A

更新日期：2019-04-17 00:00:00

abstract：:Copper mining and the byproducts associated with the industry have led to serious pollution in the Loess Plateau of China. There is a potential in improving the ecological restoration efficiency of such degraded land through combining microbial and plant remediation approaches. However, the community structure and fun...

journal_title：Frontiers in microbiology

authors： Jia T,Yao Y,Wang R,Wu T,Chai B

更新日期：2020-05-28 00:00:00

abstract：:Parasites are now known to be ubiquitous across biological systems and can play an important role in modulating algal populations. However, there is a lack of extensive information on their role in artificial ecosystems such as algal production ponds and photobioreactors. Parasites have been implicated in the demise o...

journal_title：Frontiers in microbiology

authors： Carney LT,Lane TW

更新日期：2014-06-06 00:00:00

abstract：:Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important missing ingredient during Leishmania transmission. Leishmania activel...

journal_title：Frontiers in microbiology

authors： Rogers ME

更新日期：2012-06-28 00:00:00

abstract：:Kunu is a traditional fermented single or mixed cereals-based beverage popularly consumed in many parts of West Africa. Presently, the bacterial community and mycotoxin contamination profiles during processing of various kunu formulations have never been comprehensively studied. This study, therefore, investigated the...

journal_title：Frontiers in microbiology

authors： Ezekiel CN,Ayeni KI,Ezeokoli OT,Sulyok M,van Wyk DAB,Oyedele OA,Akinyemi OM,Chibuzor-Onyema IE,Adeleke RA,Nwangburuka CC,Hajšlová J,Elliott CT,Krska R

更新日期：2019-01-09 00:00:00

abstract：:Many chronic inflammatory diseases are known to be caused by persistent bacterial or viral infections. A well-studied example is the tick-borne infection by the gram-negative spirochaetes of the genus Borrelia in humans and other mammals, causing severe symptoms of chronic inflammation and subsequent tissue damage (Ly...

journal_title：Frontiers in microbiology

authors： Binder SC,Telschow A,Meyer-Hermann M

更新日期：2012-03-22 00:00:00

abstract：:Sponges that harbor microalgal or, cyanobacterial symbionts may benefit from photosynthetically derived carbohydrates, which are rich in carbon but devoid of nitrogen, and may therefore encounter nitrogen limitation. Diazotrophic communities associated with two Caribbean sponges, Ircinia strobilina and Mycale laxissim...

journal_title：Frontiers in microbiology

authors： Zhang F,Vicente J,Hill RT

更新日期：2014-10-28 00:00:00

abstract：:Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria. It was found in previous studies that IS26 and class 1 integrons integrated on plasmids to speed the dissemination of antibiotic-r...

journal_title：Frontiers in microbiology

authors： Zhao H,Chen W,Xu X,Zhou X,Shi C

更新日期：2018-10-23 00:00:00

abstract：:Acinetobacter baumannii is one of the most important nosocomial pathogens, and thus it is required to investigate how it disseminate in hospitals and infect patients. We performed whole genome sequencing for 24 A. baumannii strains isolated successively from the blood of a single patient to evaluate whether repeated i...

journal_title：Frontiers in microbiology

authors： Kim SJ,Kim YJ,Ko KS

更新日期：2018-11-27 00:00:00

abstract：:The environment of Lake Baikal is a well-known source of microbial diversity. The strain Streptomyces sp. IB2014/011-12, isolated from samples collected at Lake Baikal, was found to exhibit potent activity against Gram-positive bacteria. Here, we report isolation and characterization of linear polyketide alpiniamide A...

journal_title：Frontiers in microbiology

authors： Paulus C,Rebets Y,Zapp J,Rückert C,Kalinowski J,Luzhetskyy A

更新日期：2018-08-22 00:00:00

abstract：:The selection of yeasts intended as starters for table olives is a complex process, including a characterization step at laboratory level and a validation at lab level and factory-scale. The characterization at lab level deals with the assessment of some technological traits (growth under different temperatures and at...

journal_title：Frontiers in microbiology

authors： Bevilacqua A,Corbo MR,Sinigaglia M

更新日期：2012-05-31 00:00:00

abstract：:Through the expression of the accessory gene regulator quorum sensing cascade, Staphylococcus aureus is able to produce an extensive array of enzymes, hemolysins and immunomodulators essential to its ability to spread through the host tissues and cause disease. Many have argued for the discovery and development of quo...

journal_title：Frontiers in microbiology

authors： Quave CL,Horswill AR

更新日期：2014-12-12 00:00:00

abstract：:The impact of subacute rumen acidosis (SARA) on the rumen bacterial community has been frequently studied in in vivo trials. Here we investigated whether these alterations can be mirrored by using the rumen simulation technique (RUSITEC) as an in vitro model for this disease. We hypothezised that the bacterial communi...

journal_title：Frontiers in microbiology

authors： Brede M,Orton T,Pinior B,Roch FF,Dzieciol M,Zwirzitz B,Wagner M,Breves G,Wetzels SU

更新日期：2020-08-07 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of Chlamydia trachomatis (C. trachomatis). Here, we used a lncRNA microarray to detect the global lncRNA expression profiles in HeLa cells transfect...

journal_title：Frontiers in microbiology

authors： Wen Y,Chen H,Luo F,Zhao L,Shu M,Su S,Zhao Y,Huang Q,Li Z

更新日期：2020-12-17 00:00:00

abstract：:There is increasing evidence that volatile organic compounds (VOCs) play an important role in the interactions between fungi and bacteria, two major groups of soil inhabiting microorganisms. Yet, most of the research has been focused on effects of bacterial volatiles on suppression of plant pathogenic fungi whereas li...

journal_title：Frontiers in microbiology

authors： Schmidt R,Etalo DW,de Jager V,Gerards S,Zweers H,de Boer W,Garbeva P

更新日期：2016-01-05 00:00:00

abstract：:The present study aimed to understand the biofilm formation mechanism of Propionibacterium acnes by analyzing the components and structure of the biofilms. P. acnes strains were isolated from the surface of explanted cardiac pacemaker devices that exhibited no clinical signs of infection. Culture tests using a simple ...

journal_title：Frontiers in microbiology

authors： Okuda KI,Nagahori R,Yamada S,Sugimoto S,Sato C,Sato M,Iwase T,Hashimoto K,Mizunoe Y

更新日期：2018-02-14 00:00:00

abstract：:The dearth of new antibiotics in the face of widespread antimicrobial resistance makes developing innovative strategies for discovering new antibiotics critical for the future management of infectious disease. Understanding the genetics and evolution of antibiotic producers will help guide the discovery and bioenginee...

journal_title：Frontiers in microbiology

authors： Stulberg ER,Lozano GL,Morin JB,Park H,Baraban EG,Mlot C,Heffelfinger C,Phillips GM,Rush JS,Phillips AJ,Broderick NA,Thomas MG,Stabb EV,Handelsman J

更新日期：2016-05-03 00:00:00

abstract：:N6-methyladenosine (m6A) plays important roles in a branch of biological and physiological processes. Accurate identification of m6A sites is especially helpful for understanding their biological functions. Since the wet-lab techniques are still expensive and time-consuming, it's urgent to develop computational method...

journal_title：Frontiers in microbiology

authors： Zhang J,Feng P,Lin H,Chen W

更新日期：2018-05-14 00:00:00

abstract：:Human campylobacteriosis is considered one of the most common foodborne diseases worldwide with poultry identified as the main source of infection accounting for 50-80% of human cases. Highly virulent Campylobacter spp., positive for the Type VI secretion system (T6SS), which have an increased ability to adhere to and...

journal_title：Frontiers in microbiology

authors： Sima F,Stratakos AC,Ward P,Linton M,Kelly C,Pinkerton L,Stef L,Gundogdu O,Lazar V,Corcionivoschi N

更新日期：2018-09-07 00:00:00

abstract：:Type IV pili (T4P) are surface-exposed protein fibers that play key roles in the bacterial life cycle via surface attachment/adhesion, biofilm formation, motility, and development. The order Myxococcales (myxobacteria) are members of the class Deltaproteobacteria and known for their large genome size and complex socia...

journal_title：Frontiers in microbiology

authors： Sharma G,Burrows LL,Singer M

更新日期：2018-07-19 00:00:00

abstract：:Helicobacter pylori does not encode the classical DsbA/DsbB oxidoreductases that are crucial for oxidative folding of extracytoplasmic proteins. Instead, this microorganism encodes an untypical two proteins playing a role in disulfide bond formation - periplasmic HP0231, which structure resembles that of EcDsbC/DsbG, ...

journal_title：Frontiers in microbiology

authors： Bocian-Ostrzycka KM,Łasica AM,Dunin-Horkawicz S,Grzeszczuk MJ,Drabik K,Dobosz AM,Godlewska R,Nowak E,Collet JF,Jagusztyn-Krynicka EK

更新日期：2015-10-08 00:00:00

abstract：:Subseafloor sedimentary environments harbor remarkably diverse microbial communities. However, it remains unknown if the deeply buried fossils in these sediments play ecological roles in deep microbial habitats, or whether the microbial communities inhabiting such fossils differ from those in the surrounding sediment ...

journal_title：Frontiers in microbiology

authors： Hoshino T,Morono Y,Terada T,Imachi H,Ferdelman TG,Inagaki F

更新日期：2011-11-17 00:00:00

abstract：:We report the case of a patient with acute necrotizing colitis due to invasive amebiasis associated with CD4 lymphopenia and impaired neutrophil responses. The course of the disease was characterized by CMV reactivation and severe and recurrent bacterial and fungal infections, which might be related to the decreased C...

journal_title：Frontiers in microbiology

authors： Ghrenassia E,Guihot A,Dong Y,Robinet P,Fontaine T,Lacombe K,Lescot T,Meyohas MC,Elbim C

更新日期：2017-02-13 00:00:00

abstract：:Biogenic transformation of Fe minerals, associated with extracellular electron transfer (EET), allows microorganisms to exploit high-potential refractory electron acceptors for energy generation. EET-capable thermophiles are dominated by hyperthermophilic archaea and Gram-positive bacteria. Information on their EET pa...

journal_title：Frontiers in microbiology

authors： Gavrilov SN,Zavarzina DG,Elizarov IM,Tikhonova TV,Dergousova NI,Popov VO,Lloyd JR,Knight D,El-Naggar MY,Pirbadian S,Leung KM,Robb FT,Zakhartsev MV,Bretschger O,Bonch-Osmolovskaya EA

更新日期：2021-01-11 00:00:00

abstract：:The VPAP30 strain was isolated as the highly predominant bacteria from an episode of massive larval mortality occurring in a commercial culture of the Chilean scallop Argopecten purpuratus. The main aims of this study were, to characterize and identify the pathogenic strain using biochemical and molecular methods to d...

journal_title：Frontiers in microbiology

authors： Rojas R,Miranda CD,Santander J,Romero J

更新日期：2016-09-20 00:00:00

abstract：:Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations involving substitutio...

journal_title：Frontiers in microbiology

authors： Kamiyama H,Izumida M,Umemura Y,Hayashi H,Matsuyama T,Kubo Y

更新日期：2018-08-27 00:00:00