Abstract：
OBJECTIVES:This systematic review and meta-analysis aimed to reveal the magnitude of neonatal sepsis and its associated factors in East Africa. METHODS:Using PRISMA guideline, we reviewed and meta-analyzed studies from Google Scholar, Cochrane library, and PubMed; last search date: October 15, 2019. Heterogeneity across the studies was estimated. The subgroup analysis was done. Publication bias was also assessed. RESULTS:A total of 26 studies with 11,239 participants are included. The pooled prevalence of neonatal sepsis in East Africa was 29.765% (95% CI 23.36-35.94). Home delivery (AOR = 2.67; 95% CI 1.15-4.00), maternal history of urinary tract infection (UTI) (AOR = 2.083; 95% CI 0.24-3.93), gestational age/(preterm) (AOR = 1.56; 95% CI 1.04-2.08), prolonged labor (AOR = 3.23; 95% CI 0.04-6.51) and PROM (AOR = 1.95; 95% CI 0.53-3.37) were identified associated factors of neonatal sepsis. CONCLUSIONS:The prevalence of neonatal sepsis in East Africa remains high. The relevant stockholders should give attention for neonates delivered from women with intranatal fever to prevent neonatal sepsis. Pregnant women should be screened for UTI. Appropriate interventions should be put in place to manage PROM to decrease the chance of ascending microorganisms.
journal_name
Int J Public Healthjournal_title
International journal of public healthauthors
Abate BB,Kasie AM,Reta MA,Kassaw MWdoi
10.1007/s00038-020-01489-xsubject
Has Abstractpub_date
2020-12-01 00:00:00pages
1623-1633issue
9eissn
1661-8556issn
1661-8564pii
10.1007/s00038-020-01489-xjournal_volume
65pub_type
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journal_title：International journal of public health
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更新日期：2017-04-01 00:00:00
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更新日期：2013-10-01 00:00:00
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更新日期：2010-04-01 00:00:00
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更新日期：2008-01-01 00:00:00
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更新日期：2017-03-01 00:00:00
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