Abstract:
:The hepatotoxicity cases due to herbal medical products have been increased in recent years. Teucrium polium (TP) (mountain germander) is one of the most popular species of the Lamiaceae family and is commonly used for increasing breast milk formation and for relieving gastrointestinal complaints in the last months of pregnancy and postpartum periods. Here are presented 3 cases of serious hepatotoxicity due to TP. Three female patients aged 33, 31, and 37 years were admitted to clinic with jaundice and serious elevated liver enzymes for a period of 2 years. The patients were using TP for approximately 40 days to 3 months. Two of the 3 used TP during their previous pregnancies and were monitored for similar complaints by another center. After discontinuation of TP and supportive care, the liver function tests were decreased to normal limits within 3 months in all 3 patients. In addition to the potential hepatotoxic effect of TP, physiological changes in the postpartum period may increase the severity of hepatotoxicity. TP should be considered in differential diagnosis in patients presenting similar history and complaints, where it is used commonly.
journal_name
Ann Saudi Medjournal_title
Annals of Saudi medicineauthors
Dag M,Özturk Z,Aydnl M,Koruk I,Kadayfç Adoi
10.5144/0256-4947.2014.541subject
Has Abstractpub_date
2014-11-01 00:00:00pages
541-3issue
6eissn
0256-4947issn
0975-4466journal_volume
34pub_type
杂志文章abstract::In this study, 103 Saudi males and 172 Saudi females were referred for medical check-up for employment purposes and/or as undergraduate students. Clinical evaluation of all participants included full cardiovascular examination, with the following investigations being performed: ECG, chest x-ray, and cross-sectional ec...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1996.417
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Toxoplasmosis, caused by Toxoplasma gondii, is diagnosed mainly by serological methods that are hindered by insufficient sensitivity. When it fails, it becomes necessary to rely on either direct detection of the parasite or DNA detection by polymerase chain reaction (PCR). We aimed to establis...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2012.14.7.1200
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Data on thyroid surgery in children are scarce. OBJECTIVE:Analyze outcome data on thyroid surgery in a pediatric population. DESIGN:Medical record review. SETTING:Tertiary health care institution. PATIENTS AND METHODS:We collected demographic and clinical data on patients 18 years or younger who had thyr...
journal_title:Annals of Saudi medicine
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doi:10.5144/0256-4947.2020.316
更新日期:2020-07-01 00:00:00
abstract::A retrospective study of 22 adult patients with dermatomyositis (DM) or polymyositis (PM) was performed. Male to female ratio was 1:2.7. Mean age of onset was 37.3 +/- (16.3) and symptoms were present for a mean of 11.2 +/- 14.6 months before diagnosis. Primary polymyositis was diagnosed in 11 (50%), primary dermatomy...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1993.525
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Fragile X syndrome is the most common cause of inherited mental retardation. Patients with fragile X syndrome show variable mental disability, typical long and narrow facial appearance with large ears and prominent fontanelle and frequent macro-orchidism. It is generally associated with a fragile site at Xq ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2000.214
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:This report describes our experience with 15 consecutive emergency cervical cerclages performed at Al Yamamah Hospital. PATIENTS AND METHODS:Between February 1994 and February 1997, 15 women with singleton pregnancies between 18 and 26 weeksâ gestation, with a cervical dilatation between 3 and 10 cm and wit...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1999.23
更新日期:1999-01-01 00:00:00
abstract:AIMS:Type 2 diabetes mellitus (T2DM) is characterized by both decreased insulin sensitivity and impaired insulin secretion. The 2 phases of insulin secretion are the first-phase insulin secretion (1st ISEC) and the second-phase insulin secretion. In this study, we tried to build clinical-metabolic models to predict the...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2015.138
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Clinical presentation of type II diabetes mellitus (DM) has frequently been observed at an early age in developing countries, probably as a result of genetic, epidemiological and demographic factors. This study aimed to investigate the pattern of familial clustering of type II DM in patients who developed cl...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1999.308
更新日期:1999-07-01 00:00:00
abstract::During December 1987 to December 1990 the incidence of neural tube defects in the Asir region located in southwestern Saudi Arabia was 0.82/1000. These results were drawn from a survey conducted of all cases of neural tube defects referred to the main hospital at Abha City (Asir Central Hospital) (ACH). Anencephaly wa...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1992.449
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Each of the metabolic syndrome (MetS) components (central obesity, hypertriglyceridemia, hypertension, low high-density lipoprotein cholesterol, and insulin resistance) may arise from an underlying disease or factors such as hormonal or pharmacological factors. These components arising seconda...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2013.566
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Patients with thalassemia may complain of numbness and weakness of the lower extremities. The aim of the study was to document whether these patients suffer from a polyneuropathy and to determine any contributing factors for the development of neuropathy. PATIENTS AND METHODS:We examined 30 patients with th...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2006.358
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Body mass index (BMI) is the most widely used measure to define obesity and predict its complications, such as diabetes and hypertension, but its accuracy and usefulness in Saudi subjects is unknown. This study aimed to assess the validity of standard BMI cut-point values in the Saudi populati...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.4103/0256-4947.57165
更新日期:2009-11-01 00:00:00
abstract::Schistosomiasis (also known as bilharzia, bilharziasis, bilharziosis or snail fever) is a human disease syndrome caused by infection from one of several species of parasitic trematodes of the genus Schistosoma. The three main species infecting humans are S haematobium, S japonicum, and S mansoni. S japonicum is most c...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.4103/0256-4947.51800
更新日期:2009-03-01 00:00:00
abstract::Two hundred twenty-four patients presenting consecutively with massive upper gastrointestinal hemorrhage were endoscoped within 24 hours to determine the site of bleeding. Outcome was evaluated in relation with presenting variables. Duodenal ulcer was found to be the most common source of bleeding. Endoscopy demonstra...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1991.539
更新日期:1991-09-01 00:00:00
abstract::Enterococci with high level of aminoglycosides resistance are being reported from different parts of the world with increasing frequency. Treatment of infections caused by such isolates is associated with a high incidence of failure or relapse. This is attributed to the loss of the synergetic effect of aminoglycosides...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1994.290
更新日期:1994-07-01 00:00:00
abstract::Placental steroid sulphatase deficiency (SSD) is an X-linked inborn error of metabolism. Congenital X-linked ichthyosis (XLI) is a genetic disorder of keratinisation caused by steroid sulphatase (STS) deficiency, which results in a scaling skin condition in male infants shortly after birth. It may be associated with f...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2018.445
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Although the rate of multiple drug resistance is high, there is no published data on the transmission rate of drug-resistant strains of Mycobacterium tuberculosis in the Aegean region of western Turkey that are based on molecular methods. METHODS:IS6110 and pTBN12 restriction fragment length polymorphism (R...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2004.102
更新日期:2004-03-01 00:00:00
abstract::A wide variety of long-term complications may be noted following conventional cancer treatment. These include overwhelming postsplenectomy sepsis syndrome, central and peripheral nervous system toxicity, cardiovascular complications, chronic liver damage, and secondary malignancy. Follow-up monitoring usually incorpor...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1997.622
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:Autosomal recessive primary microcephaly (MCPH) is a clinically and genetically heterogeneous disorder. Patients with MCPH exhibit reduced occipito-frontal head circumference and non-progressive intellectual disability. To date, 17 genes have been known as an underlying cause of MCPH in humans. ASPM (abnorma...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2016.391
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Exposure to stressful working conditions without adequate stress-coping strategies may lead to stress and even psychiatric morbidity. There are a dearth of studies on stress-coping strategies among consultant physicians in the Arabian Gulf. OBJECTIVES:Determine stress-coping strategies among consultants in ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2018.214
更新日期:2018-05-01 00:00:00
abstract::Although the medical literature contains adequate accounts of the pathophysiology of various benign prostatic disorders, it is often necessary to revisit these lesions, to reexamine the relationships between known benign lesions and more sinister, malignant disorders, in the light of new advances in our understanding ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1998.22
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Primary breast lymphoma is a rare disease. The small number of patients and the paucity of data make large-series studies difficult. We conducted a pooled analysis to evaluate the treatment outcome and prognostic factors in patients with primary breast lymphoma. METHODS:In a search of PUBMED and MEDLINE we ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2005.288
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Genomic scan analyses have suggested that the chemokine receptor cluster (CCR2, CCR3, CCR5 <300 kb span) on the short arm of chromosome 3 may contribute to susceptibility to HIV-1 infection and to the expression of a number of inflammatory diseases. Two single-nucleotide polymorphisms (SNP) an...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.4103/0256-4947.60516
更新日期:2010-03-01 00:00:00
abstract::Acute kidney injury (AKI) is one of the most challenging problems faced by clinicians in the tropics owing to its fast-changing burden. AKI in the tropics is strikingly different from that in the developed world in terms of etiology and presentation. In addition, there is a stark contrast between well-developed and po...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.4103/0256-4947.84620
更新日期:2011-09-01 00:00:00
abstract::Cerebral palsy (CP) is a common pediatric disorder occurring in about 2 to 2.5 per 1000 live births. It is a chronic motor disorder resulting from a non-progressive (static) insult to the developing brain. CP is the clinical presentation of a wide variety of cerebral cortical or sub-cortical insults occurring during t...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章,评审
doi:10.5144/0256-4947.2006.123
更新日期:2006-03-01 00:00:00
abstract::Eighteen cases of traumatic fracture dislocation were managed surgically using a technique which involved an anterior cervical approach followed by discectomy, bone graft, and insertion of a metal plate. The patients were mobilized early to prevent the usual complications of bedsores, deep vein thrombosis, pulmonary e...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1991.189
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is limited data available on the characteristics of local Saudi patients diagnosed with congestive heart failure (CHF) and on their adherence to guidelines for managing the disease. This study aimed to fill this gap. DESIGN AND SETTING:Retrospective study of patients treated at King Abd...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2012.583
更新日期:2012-11-01 00:00:00
abstract::Submucosal diathermy of the inferior turbinate (SMDIT) is a generally safe procedure to control inferior turbinate hypertrophy. We present a case of a cerebrospinal fluid (CSF) leak at the craniocervical junction after SMDIT done in another institution. A 27-year-old man presented 3 weeks after undergoing SMDIT with s...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.2018.143
更新日期:2018-03-01 00:00:00
abstract::Over a period of 14 years, 1246 patients had emergency gastroscopy because of upper gastrointestinal tract (UGIT) bleeding. The endoscopic findings in these patients showed duodenal ulcer disease (DUD) in 364 (29.2%) was the most common followed by esophageal varices in 302 (24.2%), erosive gastritis in 198 (15.9%), g...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1995.606
更新日期:1995-11-01 00:00:00
abstract::The ever-increasing incidence of diabetes mellitus is a cause for growing public health concern in both developed and developing countries. In this study, we aim to explore the special demographic and clinical features of diabetes, as seen in a large sample of Yemeni patients, and to compare these features with those ...
journal_title:Annals of Saudi medicine
pub_type: 杂志文章
doi:10.5144/0256-4947.1997.402
更新日期:1997-07-01 00:00:00