Rich Club Organization and Cognitive Performance in Healthy Older Participants.

Abstract:

:The human brain is a complex network that has been noted to contain a group of densely interconnected hub regions. With a putative "rich club" of hubs hypothesized to play a central role in global integrative brain functioning, we assessed whether hub and rich club organizations are associated with cognitive performance in healthy participants and whether the rich club might be differentially involved in cognitive functions with a heavier dependence on global integration. A group of 30 relatively older participants (range = 39-79 years of age) underwent extensive neuropsychological testing, combined with diffusion-weighted magnetic resonance imaging to reconstruct individual structural brain networks. Rich club connectivity was found to be associated with general cognitive performance. More specifically, assessing the relationship between the rich club and performance in two specific cognitive domains, we found rich club connectivity to be differentially associated with attention/executive functions-known to rely on the integration of distributed brain areas-rather than with visuospatial/visuoperceptual functions, which have a more constrained neuroanatomical substrate. Our findings thus provide first empirical evidence of a relevant role played by the rich club in cognitive processes.

journal_name

J Cogn Neurosci

authors

Baggio HC,Segura B,Junque C,de Reus MA,Sala-Llonch R,Van den Heuvel MP

doi

10.1162/jocn_a_00821

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

1801-10

issue

9

eissn

0898-929X

issn

1530-8898

journal_volume

27

pub_type

杂志文章
  • Changes in events alter how people remember recent information.

    abstract::Observers spontaneously segment larger activities into smaller events. For example, "washing a car" might be segmented into "scrubbing," "rinsing," and "drying" the car. This process, called event segmentation, separates "what is happening now? from "what just happened." In this study, we show that event segmentation ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2010.21524

    authors: Swallow KM,Barch DM,Head D,Maley CJ,Holder D,Zacks JM

    更新日期:2011-05-01 00:00:00

  • Consistent Neural Activity Patterns Represent Personally Familiar People.

    abstract::How does the brain encode and organize our understanding of the people we know? In this study, participants imagined personally familiar others in a variety of contexts while undergoing fMRI. Using multivoxel pattern analysis, we demonstrated that thinking about familiar others elicits consistent fine-grained patterns...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01151

    authors: Thornton MA,Mitchell JP

    更新日期:2017-09-01 00:00:00

  • Performance Monitoring during Visual Priming.

    abstract::Repetitive performance of single-feature (efficient or pop-out) visual search improves RTs and accuracy. This phenomenon, known as priming of pop-out, has been demonstrated in both humans and macaque monkeys. We investigated the relationship between performance monitoring and priming of pop-out. Neuronal activity in t...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01499

    authors: Westerberg JA,Maier A,Woodman GF,Schall JD

    更新日期:2020-03-01 00:00:00

  • Cerebellar transcranial direct current stimulation impairs the practice-dependent proficiency increase in working memory.

    abstract::How the cerebellum is involved in the practice and proficiency of non-motor functions is still unclear. We tested whether transcranial direct current stimulation (tDCS) over the cerebellum (cerebellar tDCS) induces after-effects on the practice-dependent increase in the proficiency of a working memory (WM) task (Stern...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.20112

    authors: Ferrucci R,Marceglia S,Vergari M,Cogiamanian F,Mrakic-Sposta S,Mameli F,Zago S,Barbieri S,Priori A

    更新日期:2008-09-01 00:00:00

  • The Prospective Sense of Agency is Rooted in Local and Global Properties of Intrinsic Functional Brain Networks.

    abstract::The sense of agency (SoA) refers to a constitutional aspect of the self describing the extent to which individuals feel in control over their actions and consequences thereof. Although the SoA has been associated with mental health and well-being, it is still unknown how interindividual variability in the SoA is embed...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01590

    authors: Di Plinio S,Perrucci MG,Ebisch SJH

    更新日期:2020-09-01 00:00:00

  • Gamma band synchronization and the formation of representations in visual word processing: evidence from repetition and homophone priming.

    abstract::The formation of an object's cortical representation seems to rely on synchronized neuronal activity within the gamma band frequency range (gamma band activity [GBA]). In this study, we investigated whether electroencephalogram (EEG) GBA, and its phase synchronization between electrodes, is necessary for the formation...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.20136

    authors: Matsumoto A,Iidaka T

    更新日期:2008-11-01 00:00:00

  • Integrated contextual representation for objects' identities and their locations.

    abstract::Visual context plays a prominent role in everyday perception. Contextual information can facilitate recognition of objects within scenes by providing predictions about objects that are most likely to appear in a specific setting, along with the locations that are most likely to contain objects in the scene. Is such id...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.20027

    authors: Gronau N,Neta M,Bar M

    更新日期:2008-03-01 00:00:00

  • The Timing of Regular Sequences: Production, Perception, and Covariation.

    abstract::The temporal structure of behavior provides information that allows the tracking of temporal regularity in the sensory and sensorimotor domains. In turn, temporal regularity allows the generation of predictions about upcoming events and to adjust behavior accordingly. These mechanisms are essential to ensure behavior ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00805

    authors: Schwartze M,Kotz SA

    更新日期:2015-09-01 00:00:00

  • Neural correlates of post-error slowing during a stop signal task: a functional magnetic resonance imaging study.

    abstract::The ability to detect errors and adjust behavior accordingly is essential for maneuvering in an uncertain environment. Errors are particularly prone to occur when multiple, conflicting responses are registered in a situation that requires flexible behavioral outputs; for instance, when a go signal requires a response ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.20071

    authors: Li CS,Huang C,Yan P,Paliwal P,Constable RT,Sinha R

    更新日期:2008-06-01 00:00:00

  • Opposing dorsal/ventral stream dynamics during figure-ground segregation.

    abstract::The visual system has been commonly subdivided into two segregated visual processing streams: The dorsal pathway processes mainly spatial information, and the ventral pathway specializes in object perception. Recent findings, however, indicate that different forms of interaction (cross-talk) exist between the dorsal a...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00497

    authors: Wokke ME,Scholte HS,Lamme VA

    更新日期:2014-02-01 00:00:00

  • Facial expressions and the evolution of the speech rhythm.

    abstract::In primates, different vocalizations are produced, at least in part, by making different facial expressions. Not surprisingly, humans, apes, and monkeys all recognize the correspondence between vocalizations and the facial postures associated with them. However, one major dissimilarity between monkey vocalizations and...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,评审

    doi:10.1162/jocn_a_00575

    authors: Ghazanfar AA,Takahashi DY

    更新日期:2014-06-01 00:00:00

  • Decoding Dynamic Brain Patterns from Evoked Responses: A Tutorial on Multivariate Pattern Analysis Applied to Time Series Neuroimaging Data.

    abstract::Multivariate pattern analysis (MVPA) or brain decoding methods have become standard practice in analyzing fMRI data. Although decoding methods have been extensively applied in brain-computer interfaces, these methods have only recently been applied to time series neuroimaging data such as MEG and EEG to address experi...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,评审

    doi:10.1162/jocn_a_01068

    authors: Grootswagers T,Wardle SG,Carlson TA

    更新日期:2017-04-01 00:00:00

  • Transcranial direct current stimulation enhances verbal working memory training performance over time and near transfer outcomes.

    abstract::Studies attempting to increase working memory (WM) capacity show promise in enhancing related cognitive functions but have also raised criticism in the broader scientific community given the inconsistent findings produced by these studies. Transcranial direct current stimulation (tDCS) has been shown to enhance WM per...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1162/jocn_a_00657

    authors: Richmond LL,Wolk D,Chein J,Olson IR

    更新日期:2014-11-01 00:00:00

  • The strategic control of gaze direction in the Tower-of-London task.

    abstract::In this paper, we describe a novel approach to the study of problem solving involving the detailed analysis of natural scanning eye movements during the "one-touch" Tower-of-London (TOL) task. We showed subjects a series of pictures depicting two arrangements of colored balls in pockets within the upper and lower halv...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/089892900562499

    authors: Hodgson TL,Bajwa A,Owen AM,Kennard C

    更新日期:2000-09-01 00:00:00

  • Reward-Sensitive Basal Ganglia Stabilize the Maintenance of Goal-Relevant Neural Patterns in Adolescents.

    abstract::Maturation of basal ganglia (BG) and frontoparietal circuitry parallels developmental gains in working memory (WM). Neurobiological models posit that adult WM performance is enhanced by communication between reward-sensitive BG and frontoparietal regions, via increased stability in the maintenance of goal-relevant neu...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01572

    authors: Hubbard NA,Romeo RR,Grotzinger H,Giebler M,Imhof A,Bauer CCC,Gabrieli JDE

    更新日期:2020-08-01 00:00:00

  • "Do you see yonder cloud?"--On priming concepts, a new test, and a familiar outcome. Reply to Lucas et al.: "Familiarity or conceptual priming? Good question! Comment on Stenberg, Hellman, Johansson, and Rosén (2009)".

    abstract::Lucas, Voss, and Paller sympathize with our intentions but disagree with our findings. They argue that a relation between frequency and conceptual priming may have been obscured by methodological details in our second experiment, therefore failing to complete a bridge between conceptual priming and FN400 with name fre...

    journal_title:Journal of cognitive neuroscience

    pub_type: 评论,杂志文章

    doi:10.1162/jocn.2009.21268

    authors: Stenberg G,Johansson M,Hellman J,Rosén I

    更新日期:2010-04-01 00:00:00

  • Feature diagnosticity affects representations of novel and familiar objects.

    abstract::Many features can describe a concept, but only some features define a concept in that they enable discrimination of items that are instances of a concept from (similar) items that are not. We refer to this property of some features as feature diagnosticity. Previous work has described the behavioral effects of feature...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00661

    authors: Hsu NS,Schlichting ML,Thompson-Schill SL

    更新日期:2014-12-01 00:00:00

  • Long-term memories bias sensitivity and target selection in complex scenes.

    abstract::In everyday situations, we often rely on our memories to find what we are looking for in our cluttered environment. Recently, we developed a new experimental paradigm to investigate how long-term memory (LTM) can guide attention and showed how the pre-exposure to a complex scene in which a target location had been lea...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00294

    authors: Patai EZ,Doallo S,Nobre AC

    更新日期:2012-12-01 00:00:00

  • A model that accounts for activity prior to sensory inputs and responses during matching-to-sample tasks.

    abstract::Neural network models were examined during delayed matching-to-sample tasks (DMS), and neurons in a monkey's prefrontal cortex were studied during the performance of comparable tasks. In DMS, various input stimuli follow a sample stimulus, and an output should occur whenever the sample reappears. Our previous models h...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/089892900562255

    authors: Moody SL,Wise SP

    更新日期:2000-05-01 00:00:00

  • Task-relevant output signals are sent from monkey dorsolateral prefrontal cortex to the superior colliculus during a visuospatial working memory task.

    abstract::Visuospatial working memory is one of the most extensively investigated functions of the dorsolateral prefrontal cortex (DLPFC). Theories of prefrontal cortical function have suggested that this area exerts cognitive control by modulating the activity of structures to which it is connected. Here, we used the oculomoto...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21067

    authors: Johnston K,Everling S

    更新日期:2009-05-01 00:00:00

  • Egocentric spaw representation in early vision.

    abstract::Abstract Recent physiological experiments have shown that the responses of many neurons in V1 and V3a are modulated by the direction of gaze. We have developed a neural network model of the hierarchy of maps in visual cortex to explore the hypothesis that visual features are encoded in egocentric (spatio-topic) coordi...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.1993.5.2.150

    authors: Pouget A,Fisher SA,Sejnowski TJ

    更新日期:1993-04-01 00:00:00

  • Visual experience specifically regulates synaptic molecules in rat visual cortex.

    abstract::Abstract To study environmental modulation of synaptic molecular structure, the major postsynaptic density protein (mPSDp) from rat visual cortex was monitored. This membrane component, a Ca(2+)/calmodulin-dependent protein kinase subunit, was measured during normal postnatal development and after visual deprivation. ...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.1991.3.3.252

    authors: Schoups AA,Black IB

    更新日期:1991-07-01 00:00:00

  • Feedback-related negativity codes prediction error but not behavioral adjustment during probabilistic reversal learning.

    abstract::We assessed electrophysiological activity over the medial frontal cortex (MFC) during outcome-based behavioral adjustment using a probabilistic reversal learning task. During recording, participants were presented two abstract visual patterns on each trial and had to select the stimulus rewarded on 80% of trials and t...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2010.21456

    authors: Chase HW,Swainson R,Durham L,Benham L,Cools R

    更新日期:2011-04-01 00:00:00

  • Subordinate categorization enhances the neural selectivity in human object-selective cortex for fine shape differences.

    abstract::There is substantial evidence that object representations in adults are dynamically updated by learning. However, it is not clear to what extent these effects are induced by active processing of visual objects in a particular task context on top of the effects of mere exposure to the same objects. Here we show that th...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2009.21089

    authors: Gillebert CR,Op de Beeck HP,Panis S,Wagemans J

    更新日期:2009-06-01 00:00:00

  • Neurophysiological correlates of comprehending emotional meaning in context.

    abstract::Although the neurocognitive mechanisms of nonaffective language comprehension have been studied extensively, relatively less is known about how the emotional meaning of language is processed. In this study, electrophysiological responses to affectively positive, negative, and neutral words, presented within nonconstra...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2008.21151

    authors: Holt DJ,Lynn SK,Kuperberg GR

    更新日期:2009-11-01 00:00:00

  • Electrophysiological Correlates of Refreshing: Event-related Potentials Associated with Directing Reflective Attention to Face, Scene, or Word Representations.

    abstract::Refreshing is the component cognitive process of directing reflective attention to one of several active mental representations. Previous studies using fMRI suggested that refresh tasks involve a component process of initiating refreshing as well as the top-down modulation of representational regions central to refres...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_00823

    authors: Johnson MR,McCarthy G,Muller KA,Brudner SN,Johnson MK

    更新日期:2015-09-01 00:00:00

  • Leveling the Field for a Fairer Race between Going and Stopping: Neural Evidence for the Race Model of Motor Inhibition from a New Version of the Stop Signal Task.

    abstract::The stop signal task (SST) is the gold standard experimental model of inhibitory control. However, neither SST condition-contrast (stop vs. go, successful vs. failed stop) purely operationalizes inhibition. Because stop trials include a second, infrequent signal, the stop versus go contrast confounds inhibition with a...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn_a_01503

    authors: Dykstra T,Waller DA,Hazeltine E,Wessel JR

    更新日期:2020-04-01 00:00:00

  • Brain Potentials during Memory Retrieval Provide Neurophysiological Support for the Distinction between Conscious Recollection and Priming.

    abstract::Event-related brain potentials were recorded from subjects as they attempted to identify words displayed tachistoscopically. Words that had also been presented a few minutes earlier in a different context were identified more often than were words that had not been presented before. This priming effect was observed fo...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.1992.4.4.375

    authors: Paller KA,Kutas M

    更新日期:1992-10-01 00:00:00

  • Sublexical properties of spoken words modulate activity in Broca's area but not superior temporal cortex: implications for models of speech recognition.

    abstract::Many models of spoken word recognition posit that the acoustic stream is parsed into phoneme level units, which in turn activate larger representations [McClelland, J. L., & Elman, J. L. The TRACE model of speech perception. Cognitive Psychology, 18, 1-86, 1986], whereas others suggest that larger units of analysis ar...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2011.21620

    authors: Vaden KI Jr,Piquado T,Hickok G

    更新日期:2011-10-01 00:00:00

  • A process-specific functional dissociation of the amygdala in emotional memory.

    abstract::Converging evidence highlights the important role of the amygdala in the enhanced memory for emotional material. However, it is unknown whether any regional and/or hemispheric specificity exists regarding its involvement in the different memory stages, such as encoding and retrieval. We directly addressed this issue b...

    journal_title:Journal of cognitive neuroscience

    pub_type: 杂志文章

    doi:10.1162/jocn.2006.18.8.1359

    authors: Sergerie K,Lepage M,Armony JL

    更新日期:2006-08-01 00:00:00