The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials.

Abstract:

:The novel oral anticoagulants (NOACs) have rapidly emerged as an alternative therapy to warfarin. Several recent phase 3 randomized control trials have demonstrated the efficacy and safety of the NOACs in the treatment for patients with nonvalvular atrial fibrillation. As the NOACs are incorporated in clinical practice, questions have begun to arise concerning their optimal use in commonly encountered situations. In this review, we provide a summary of the available evidence from the phase 3 randomized control trials specifically with regard to 1 such scenario, the periprocedural management of NOACs, with a goal of providing guidance for practicing clinicians.

journal_name

Am Heart J

journal_title

American heart journal

authors

Krishnamoorthy A,Sherwood MW,Lopes RD,Becker RC

doi

10.1016/j.ahj.2014.12.008

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

315-22

issue

3

eissn

0002-8703

issn

1097-6744

pii

S0002-8703(14)00745-5

journal_volume

169

pub_type

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