Abstract:
:Methods for calculating the activity to be administered during yttrium-90 radioembolization (RE) are largely based on empirical toxicity and efficacy analyses, rather than dosimetry. At the same time, it is recognized that treatment planning based on proper dosimetry is of vital importance for the optimization of the results of RE. The heterogeneous and often clustered intrahepatic biodistribution of millions of point-source radioactive particles poses a challenge for dosimetry. Several studies found a relationship between absorbed doses and treatment outcome, with regard to both toxicity and efficacy. This should ultimately lead to improved patient selection and individualized treatment planning. New calculation methods and imaging techniques and a new generation of microspheres for image-guided RE will all contribute to these improvements. The aim of this review is to give insight into the latest and most important developments in RE dosimetry and to suggest future directions on patient selection, individualized treatment planning, and study designs.
journal_name
Cardiovasc Intervent Radioljournal_title
Cardiovascular and interventional radiologyauthors
Smits ML,Elschot M,Sze DY,Kao YH,Nijsen JF,Iagaru AH,de Jong HW,van den Bosch MA,Lam MGdoi
10.1007/s00270-014-1042-7subject
Has Abstractpub_date
2015-04-01 00:00:00pages
261-9issue
2eissn
0174-1551issn
1432-086Xjournal_volume
38pub_type
杂志文章,评审abstract:PURPOSE:We report our experience of the safety of partial recanalization of the portal vein using a novel endovascular radiofrequency (RF) catheter for portal vein tumor thrombosis. METHODS:Six patients with liver cancer and tumor thrombus in the portal vein underwent percutaneous intravascular radiofrequency ablation...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-012-0451-8
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Radioembolization has emerged as a treatment modality for patients with primary and secondary liver tumours. This observational study CIRT-FR (CIRSE Registry for SIR-Spheres Therapy in France) aims to evaluate real-life clinical practice on all patients treated with transarterial radioembolization (TARE) using ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-020-02643-x
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To evaluate the origins of feeders of hepatocellular carcinoma (HCC) in the caudate lobe (S1). MATERIALS AND METHODS:Eighty-eight HCCs (mean diameter 21.4 mm) were treated by chemoembolization. The tumor-feeding caudate artery was confirmed when a tumor stain was demonstrated on angiogram and iodized oil was a...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-010-0036-3
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To evaluate the effect of previous transarterial iodized oil tissue marking (ITM) on technical parameters, three-dimensional (3D) computed tomographic (CT) rendering of the electroporation zone, and histopathology after CT-guided irreversible electroporation (IRE) in an acute porcine liver model as a potential ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-014-0910-5
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To present a series of cases of non-cirrhotic patients with symptomatic massive portal thrombosis treated by percutaneous techniques. All patients underwent a TIPS procedure in order to maintain the patency of the portal vein by facilitating the outflow. METHODS:A total of six patients were treated for thrombo...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-004-0241-z
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:Post-EVAR surveillance has a major impact upon patients, carers and healthcare resources. We hypothesised that elective indication, on-IFU anatomy, use of a modern device or normal first CTA, or a combination of these categories, might predict a rate of secondary intervention low enough to alter current su...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-016-1303-8
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND AND AIMS:Complications of portal hypertension, such as variceal hemorrhage and ascites, are associated with significant increases in both mortality and complications during pregnancy. Transjugular intrahepatic portosystemic shunt (TIPS) is a well-established procedure for treating portal hypertension, but th...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-015-1053-z
更新日期:2015-10-01 00:00:00
abstract::The purpose of this study was to assess the role of hepatic arterial embolization (HAE) and chemoembolization (HACE) in patients with large-volume liver metastases. Patients with metastatic neuroendocrine tumors, melanomas, or gastrointestinal stromal tumors (GISTs) with >75% liver involvement who underwent HAE or HAC...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-007-9186-3
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To describe the technique and feasibility of renal artery angioplasty and stenting from the radial artery. METHODS:A series of 19 patients were evaluated for transradial renal artery intervention. Procedures were performed using carbon dioxide gas (CO2) as the preferred angiographic contrast agent. Interventio...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-001-0114-7
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To compare the feasibility, safety, and efficacy with small and large irinotecan drug-eluting beads (DEBIRI) for treating hepatic colorectal metastases. METHODS:Using our prospectively maintained, multi-center, intra-arterial therapy registry, we identified 196 patients treated with a combination of large bead...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00270-014-1011-1
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:To address the feasibility of prophylactic temporary occlusion of the cystic artery using a detachable coil during 90Y radioembolization. MATERIALS AND METHODS:From January 2012 to October 2016, nine patients underwent temporary occlusion of the cystic artery during 90Y radioembolization. Based on the planning...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-017-1688-z
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:The purpose of the study is to report 12-month efficacy and safety results from the subgroup of Japanese patients in the prospective IMPERIAL 2:1 randomized controlled trial (RCT). METHODS:The global IMPERIAL RCT was designed to compare performance of the Eluvia Drug-Eluting Vascular Stent System (Boston Scien...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00270-019-02355-x
更新日期:2020-02-01 00:00:00
abstract::An aneurysm of the right renal artery was discovered in a patient suffering from cerebral arterial angiodysplasia and arterial hypertension. The aneurysm was large necked, which made selective endovascular treatment very difficult. To perform the embolization of the aneurysm, a balloon remodelling technique was used. ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s002700010049
更新日期:2000-05-01 00:00:00
abstract::Substantial improvements have been made in the systemic treatment of colorectal cancer over the last two decades. Median overall survival (OS) of patients with metastatic colorectal cancer (mCRC) has been constantly increased and the most recent first-line studies exceeded the 30-month median overall survival. The sta...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,评审
doi:10.1007/s00270-019-02278-7
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To assess the role of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) in patients with hepatocellular carcinoma (HCC) and transjugular intrahepatic portosystemic shunts (TIPS). METHODS:Between January 1999 and September 2004, 6 patients with HCC and TIPS were treated wi...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-005-0063-7
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To prospectively evaluate safety and efficacy of a novel vascular closure device (Glubran 2 Seal) after peripheral angiography in patients with peripheral arterial occlusive disease (PAOD). METHODS:From December 2010 to June 2011, all consecutive patients with PAOD undergoing peripheral angiography were prospe...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-012-0428-7
更新日期:2013-04-01 00:00:00
abstract::We report about a patient presenting with back pain 4 months after an uneventful endovascular implantation of an aortic stent graft. Computed tomography scan revealed a migration of the stent with consecutive endoleakage, kink formation, and movement of the stent toward the spine, which caused destruction of the aorti...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-013-0695-y
更新日期:2013-12-01 00:00:00
abstract::During the placement of a Gianturco coil in a patient with renal cell carcinoma, the cotton threads of the steel coil remained fixed to the introducing catheter tip, and the coil was unintentionally withdrawn from the selected renal artery back into the aorta. By snare technique the coil was caught with another angiog...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02551979
更新日期:1980-01-01 00:00:00
abstract::An intrahepatic arterioportal fistula causing portal hypertension was successfully palliated with steel coils. The patient remains well 2 1/2 years after embolization. The 13 previously reported cases of transcatheter embolization of large intrahepatic arterioportal fistulae are reviewed. Percutaneous transcatheter em...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章,评审
doi:10.1007/BF02577034
更新日期:1988-10-01 00:00:00
abstract::The Kimray-Greenfield inferior vena cava filter, which is used to prevent pulmonary embolization from the pelvis and lower extremities, has a high patency rate and a low complication rate. In one patient, however, thrombus formation at the apex of the filter during introduction resulted in the filter's failure to open...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552427
更新日期:1981-01-01 00:00:00
abstract::Stent-assisted coil embolization is a well-described technique for the treatment of wide-necked intracranial aneurysms. We describe a modification of this technique used successfully to occlude a wide-necked internal iliac artery aneurysm. ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-009-9675-7
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:Two stent types (a new Wallstent and a Z-stent) were investigated in 30 patients with recurrent malignant superior vena caval syndrome (SVCS). METHODS:Eligibility requirements were that the patient had recurrent symptoms after appropriate radiation therapy, chemotherapy, or both; >/= 75% of the vessel was occl...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577610
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of a newly developed fully covered irradiation stent (FCIS) compared with a partially covered irradiation stent (PCIS) in patients with unresectable malignant dysphagia. MATERIALS AND METHODS:Data of 195 patients [158 (81.0%) males, median age of 75 years (range 49-89 years)] ...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-019-02252-3
更新日期:2019-08-01 00:00:00
abstract::Intraarterial administration of chemotherapeutic agents provides greater local concentration at the tumor site without increased systemic toxicity. Although intravenous infusion of cisplatin is known to cause peripheral neuropathy and intraarterial administration has been reported to cause lumbosacral plexopathy, brac...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577128
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Large hepatic hemangiomas can cause symptoms such as pain and bleeding. No consensus currently exists on the optimal management of large and symptomatic hemangiomas. The purpose of this study was to evaluate the role of transarterial bleomycin-lipiodol embolization (B/LE) in the treatment of symptomatic larg...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-018-2010-4
更新日期:2018-11-01 00:00:00
abstract::The purpose of this study was to determine radiological or physical factors to predict the risk of residual mass or local recurrence of primary and secondary hepatic tumors treated by radiofrequency ablation (RFA). Eighty-two patients, with 146 lesions (80 hepatocellular carcinomas, 66 metastases), were treated by RFA...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-007-9208-1
更新日期:2008-01-01 00:00:00
abstract::Varicography, consisting of direct puncture and injection into a varicosity, is the diagnostic procedure of choice in the assessment of varicose veins of the lower limbs. It must be performed in cases of recurrent posterior varicose veins of the leg, after negative ascending phlebography, when looking for possible dra...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02577400
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness of transcatheter arterial embolization (TAE) for gastrointestinal (GI) bleeding caused by GI lymphoma. MATERIALS AND METHODS:The medical records of 11 patients who underwent TAE for GI bleeding caused by GI lymphoma between 2001 and 2015 were reviewed retrospectively. RESULTS:A t...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-016-1422-2
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To identify whether long-term symptom relief and stent patency vary with the use of covered versus uncovered stents for the treatment of benign SVC obstruction. METHODS AND MATERIALS:We retrospectively identified all patients with benign SVC syndrome treated to stent placement between January 2003 and December...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/s00270-018-1906-3
更新日期:2018-05-01 00:00:00
abstract::Polyurethane Bayer was tested as an occlusive agent for experimental embolization in postmortem and postnephrectomy kidneys which served as a tumor model. Coaxial and balloon catheters were used for the embolization. To make polyurethane radiopaque, the material was labeled with different water-soluble, oily and solid...
journal_title:Cardiovascular and interventional radiology
pub_type: 杂志文章
doi:10.1007/BF02552764
更新日期:1983-01-01 00:00:00