Electrophysiologic assessment of auditory and visual function in the newborn.

abstract：:Neonatology has optimized medical outcomes for high-risk newborns yet neurodevelopmental outcomes continue to be a concern. Basic science, clinical research, and environmental design perspectives have shown the impact of the caregiving environment on the developing brain and the role of professional caregivers in prov...

journal_title：Clinics in perinatology

authors： Browne JV

更新日期：2011-12-01 00:00:00

abstract：:Multiple pregnancies represent a state of magnified nutritional requirements, resulting in a greater nutrient drain on maternal resources and an accelerated depletion of nutritional reserves. Maternal weight gain to 20 weeks and between 20 and 28 weeks has the greatest effect on birthweight in twin and triplet pregnan...

journal_title：Clinics in perinatology

authors： Luke B

更新日期：2005-06-01 00:00:00

abstract：:Although therapies in addition to whole-body cooling are being developed to treat the neonate at risk for hypoxic-ischemic encephalopathy, we have no quickly measured serum inflammatory or neuronal biomarkers to acutely and accurately identify brain injury or to follow the efficacy of therapy. This review covers infla...

journal_title：Clinics in perinatology

authors： Chalak LF

更新日期：2016-09-01 00:00:00

abstract：:Moderate preterm, late preterm, and early term deliveries represent a major and growing public health concern. These deliveries are associated with significant financial burden and pose serious risks to mothers and newborns. Women who deliver at moderate and late gestational ages in one pregnancy are at increased risk...

journal_title：Clinics in perinatology

authors： Ananth CV,Friedman AM,Gyamfi-Bannerman C

更新日期：2013-12-01 00:00:00

abstract：:Preterm births remain a major cause of neonatal morbidity and mortality despite our efforts over the past several decades. Our improved understanding of the complex mechanisms surrounding preterm labor, however, has resulted in the development of numerous biologic and clinical predictors of spontaneous preterm births....

journal_title：Clinics in perinatology

authors： Lu GC,Goldenberg RL

更新日期：2000-06-01 00:00:00

abstract：:Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...

journal_title：Clinics in perinatology

authors： Carr BR,Gant NF

更新日期：1983-10-01 00:00:00

abstract：:The extensive data from animal models of BPD and specific aspects of lung injury have helped to expand and refine the concept of pathogenesis introduced by Northway et al. Given the complexity and heterogeneity of the human illness, it is unreasonable to presume that any single model or research group could elucidate ...

journal_title：Clinics in perinatology

authors： deLemos RA,Coalson JJ

更新日期：1992-09-01 00:00:00

abstract：:Familial hypothyroidism results from both thyroidal and extrathyroidal dysfunction. Specific intrathyroidal abnormalities in thyroid hormone synthesis causing goitrous hypothyroidism are iodide trap defect, organification defect, "coupling" defect, iodoprotein defect, and dehalogenase defect. The diagnostic studies fo...

journal_title：Clinics in perinatology

authors： Jackson IM

更新日期：1976-03-01 00:00:00

abstract：:The specific pathologic processes preceding the onset of irreversible cerebral injury seem to be a combination of several complex mechanisms due to the severity and duration of the insult to the biochemical modifications in the brain. An early diagnosis of the newborn at high risk for brain damage is relevant for prev...

journal_title：Clinics in perinatology

authors： Buonocore G,Perrone S

更新日期：2004-03-01 00:00:00

abstract：:This article examines the role of biologic and environmental factors in determining the long-term outcomes of extremely low-birth weight infants. Research focusing on follow-up to at least 4 years of age is reviewed. Methodologic issues related to sampling, the use of control groups, and diagnostic criteria are also d...

journal_title：Clinics in perinatology

authors： Lester BM,Miller-Loncar CL

更新日期：2000-06-01 00:00:00

abstract：:The last decades of bilirubin research seem to have clarified the basic mechanisms by which bilirubin enters the brain. Clinical studies have so far failed to show any value of the presently known risk factors in predicting bilirubin toxicity in the newborn infant, however. This indicates that bilirubin entry into the...

journal_title：Clinics in perinatology

authors： Bratlid D

更新日期：1990-06-01 00:00:00

abstract：:Phototherapy is now the preferred method of treatment for neonatal hyperbilirubinemia by virtue of its noninvasive nature and its relative freedom from major complications. It is also convenient, easy to use, and inexpensive in terms of personnel, equipment, and disposals. Long-term experience with phototherapy has de...

journal_title：Clinics in perinatology

authors： Tan KL

更新日期：1991-09-01 00:00:00

abstract：:Neutropenia is a relatively common problem in the NICU, recognized in as many as 8% of patients at some time during their hospital stay. In most instances, neutropenia among NICU patients is of short duration and has little influence on outcome. In other cases it is prolonged and severe, and constitutes a serious anti...

journal_title：Clinics in perinatology

authors： Christensen RD,Calhoun DA,Rimsza LM

更新日期：2000-09-01 00:00:00

abstract：:It is now recognized that pregnancy is associated with significant changes in maternal thyroid function that are largely mediated by the placenta. The author summarizes the understanding of these changes during pregnancy and follows with a discussion of fetal thyroid system ontogenesis. ...

journal_title：Clinics in perinatology

authors： Fisher DA

更新日期：1983-10-01 00:00:00

abstract：:There were approximately 2 million deaths worldwide from tuberculosis in 1997, 98% of them in developing countries. Factors implicated in the resurgence of tuberculosis in the United States in the late 80s and early 90s included increased immigration from countries with high prevalence, HIV infection, emergence of res...

journal_title：Clinics in perinatology

authors： Laibl VR,Sheffield JS

更新日期：2005-09-01 00:00:00

abstract：:Historically, researchers studying the field of sleep have been divided into two main groups. The first group of sleep studies was based on behaviors and behavioral sleep. The second group of researchers based their studies on electroencephalogram EEG patterns and changes. With technologic advancements, a third group ...

journal_title：Clinics in perinatology

authors： Graven S

更新日期：2006-09-01 00:00:00

abstract：:The fetal environment is thus well suited for normal growth and development with oxygen availability exceeding oxidative needs. With impairments in blood gas exchange this excess oxygen acts as a "margin of safety," providing for the maintenance of oxidative metabolism through increases in fractional O2 extraction, al...

journal_title：Clinics in perinatology

authors： Richardson BS

更新日期：1989-09-01 00:00:00

abstract：:The phenomenal developments in molecular genetics and technological refinements which have occurred over the past decade are revolutionizing the area of prenatal genetics. State-of-the-art care commences with comprehensive preconceptional counseling. Prenatal diagnosis is now feasible from the moment of conception onw...

journal_title：Clinics in perinatology

authors： Plouffe L Jr,Donahue J

更新日期：1994-12-01 00:00:00

abstract：:Congenital heart defects (CHDs) are structural abnormalities of the heart and great vessels that are present from birth. The presence or absence of extracardiac anomalies has historically been used to identify patients with possible monogenic, chromosomal, or teratogenic CHD causes. These distinctions remain clinicall...

journal_title：Clinics in perinatology

authors： Cowan JR,Ware SM

更新日期：2015-06-01 00:00:00

abstract：:Preterm birth is a major complication of pregnancy and remains a leading cause of neonatal morbidity and mortality worldwide. Improvements in the authors' understanding of the pathophysiology of preterm labor have led to the development of novel diagnostic tools of use to identify women at greatest risk for preterm bi...

journal_title：Clinics in perinatology

authors： Ramsey PS,Andrews WW

更新日期：2003-12-01 00:00:00

abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1982-06-01 00:00:00

abstract：:Total parenteral nutrition permits normal growth and development of the infant during the adaptive phase of the short bowel syndrome. Skilled nutritional support combined with a variety of medical and surgical manipulations facilitates survival of infants with as little as 15 to 20 cm of intestinal length. ...

journal_title：Clinics in perinatology

authors： Ziegler MM

更新日期：1986-03-01 00:00:00

abstract：:Decades of research have led to the understanding of neonatal pulmonary physiology and have influenced the clinical care that neonatologists provide to the sick newborn. Advances in microprocessor technology have allowed for clinical access of the research-based measurements of neonatal pulmonary functions. These eval...

journal_title：Clinics in perinatology

authors： Bhutani VK,Sivieri EM

更新日期：2001-09-01 00:00:00

abstract：:Based on the authors' review of the literature on pediatric postoperative pain assessment with special attention to groups of vulnerable infants, this article (1) reports on type of surgery and its relationship to postoperative pain intensity; (2) reviews the characteristics of existing postoperative pain instruments ...

journal_title：Clinics in perinatology

authors： van Dijk M,Peters JW,Bouwmeester NJ,Tibboel D

更新日期：2002-09-01 00:00:00

abstract：:The increasing numbers of children born to HIV-infected women poses formidable problems for maternal and child health programs throughout the world. Between 20% and 40% of these children will be infected with HIV and most are expected to die by the age of 5 years as a result. The vast majority of the uninfected childr...

journal_title：Clinics in perinatology

authors： Chin J

更新日期：1994-03-01 00:00:00

abstract：:Pulmonary hypertension in the perinatal period can present acutely (persistent pulmonary hypertension of the newborn) or chronically. Clinical and echocardiographic diagnosis of acute pulmonary hypertension is well accepted but there are no broadly validated criteria for echocardiographic diagnosis of pulmonary hypert...

journal_title：Clinics in perinatology

authors： Keller RL

更新日期：2016-03-01 00:00:00

abstract：:Several limitations and controversies surround the definition of hypotension; however, it remains one of the most common problems faced by neonates. Approximately 15% to 30% of neonates with hypotension fail to respond to volume and/or vasopressor or inotropes. They are considered to have refractory hypotension. Altho...

journal_title：Clinics in perinatology

authors： Kumbhat N,Noori S

更新日期：2020-09-01 00:00:00

abstract：:Despite the fact that hypoglycemia is an extremely common disorder of the newborn, consensus has been difficult to reach regarding definition, diagnosis, outcome, and treatment. With improved neuroradiologic techniques, such as MRI and PET scanning becoming increasingly available, studies to determine the correlation ...

journal_title：Clinics in perinatology

authors： Yager JY

更新日期：2002-12-01 00:00:00

abstract：:This article describes the early history of the "boarder baby" phenomenon through the late 1980s and early 1990s. The characteristics of the recent "boarder baby" population and of the problem are described with particular emphasis on the role of alcohol and drug abuse and the historical lack of coordination between h...

journal_title：Clinics in perinatology

authors： Maza PL

更新日期：1999-03-01 00:00:00

abstract：:Neonatal stress responses have been investigated only in recent years. Term neonates mount substantial hormonal and metabolic responses, which are distinct from those of adult patients. These responses can be altered significantly by the effects of prematurity, the effects of graded surgical stress, and the anesthetic...

journal_title：Clinics in perinatology

authors： Anand KJ

更新日期：1990-03-01 00:00:00