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Hyperbaric oxygen treatment outcome for different indications from a single center.

Abstract：

BACKGROUND:Hyperbaric oxygen (HBO) is used as an adjunctive therapy for a variety of indications. However, there is a lack of high-quality research evaluating HBO treatment outcomes for different indications available in the current literature. METHODS:We retrospectively reviewed all patients who underwent HBO therapy at a single hyperbaric center from January 2010 to December 2013 using predetermined criteria to analyze successful, improved, or failed treatment outcomes for the following indications: chronic refractory osteomyelitis, diabetic foot ulcer, failed flap or skin graft, osteoradionecrosis, soft tissue radiation necrosis, and multiple coexisting indications. RESULTS:Among the included 181 patients treated with adjunctive HBO at our center, 81.8% had either successful or improved treatment outcomes. A successful or improved outcome was observed in 82.6% of patients treated for chronic refractory osteomyelitis (n = 23), 74.1% for diabetic foot ulcer (n = 27), 75.7% for failed flap or skin graft (n = 33), 95.7% for osteoradionecrosis (n = 23), 88.1% for soft tissue radiation necrosis (n = 42), and 72.4% for multiple coexisting indications (n = 29). Among 4 patients treated for other indications, 100% of the cases were either successful or improved. CONCLUSIONS:This study has provided a comprehensive outcome survey of using HBO for the previously mentioned indications at our center. It supplements the literature with more evidence to support the consideration of HBO in different indications.

journal_name

Ann Vasc Surg

journal_title

Annals of vascular surgery

authors

Skeik N,Porten BR,Isaacson E,Seong J,Klosterman DL,Garberich RF,Alexander JQ,Rizvi A,Manunga JM Jr,Cragg A,Graber J,Alden P,Sullivan T

doi

10.1016/j.avsg.2014.07.034

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

206-14

issue

2

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(14)00529-9

journal_volume

29

pub_type

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