Prediction of compartment syndrome based on analysis of biochemical parameters.

Abstract:

BACKGROUND:The possibility of predicting severe compartment syndrome using simple biochemical parameters was evaluated in a single-center study of 55 patients who presented with acute femoral embolism and who were treated with open surgical embolectomy. METHODS:Parameters related to tissue damage and oxidative metabolism (i.e., lactate, bilirubin, myoglobin, uric acid, glucose, and fibrinogen) were monitored in ipsilateral femoral vein blood. RESULTS:Several statistically significant predictors of relevant compartment syndrome after surgical reperfusion were found, including lactate, uric acid, transcutaneous oxygen pressure, bilirubin, intrafascial pressure, and serum myoglobin. Glycemia and serum albumin did not significantly change over time. CONCLUSIONS:The lactate concentration in femoral vein blood sampled during surgical embolectomy can be used for the stratification of additional postoperative risk of clinically significant compartment syndrome complicating reperfusion after acute embolism of the femoral artery.

journal_name

Ann Vasc Surg

authors

Mitas P,Vejrazka M,Hruby J,Spunda R,Pecha O,Lindner J,Spacek M

doi

10.1016/j.avsg.2012.12.006

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

170-7

issue

1

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(13)00322-1

journal_volume

28

pub_type

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