The histology of seeded PTFE grafts in humans.


:To define the histology of PTFE femoral-popliteal grafts seeded with enzymatically-derived endothelium, we examined light level and selected scanning electron micrographs of 20 graft biopsies. Thirteen grafts were chronically occluded and the midgraft samples had a thin lining of fibrin with scattered erythrocytes and leukocytes. One anastomotic sample showed a similar pattern, while three others had neointimal fibrous hyperplasia. Six of the seven remaining midgraft samples demonstrated confluent endothelial healing over parts of the flow surface. The cells were commonly distributed along one side of the graft as viewed in cross-section. Distribution patterns were not improved by changing from a single inoculum with two graft rotation-incubation periods to a sequential inoculation separated by a graft rotation. Circumferential distribution was achieved in one instance in which inoculation was characterized by a relatively high cell density. No luminal endothelium was seen when inoculation cell densities were very low. Smooth muscle cells and fibroblasts were not seen in the subendothelial "inner capsules" of the midgrafts. We conclude that endothelialization occurs in a high proportion of seeded PTFE grafts in humans, that the donor vein surface area should measure at least 5.25% of the inoculated graft surface, that further modifications in the seeding technique will be required to achieve consistent circumferential endothelial distribution, that subendothelial smooth muscle cell invasion is uncommon in the midgraft, but that anastomotic neointimal fibrous hyperplasia probably contributed to some graft failures.


Ann Vasc Surg


Herring MB,LeGrand DR




Has Abstract


1989-04-01 00:00:00














  • Intermediate follow-up after endovascular aneurysm repair: can we forgo CT scanning in certain patients?

    abstract::Current recommendations for follow-up after endovascular repair of abdominal aortic aneurysms (EVAR) include yearly computed tomographic (CT) scans after the first year. We hypothesize that this is unnecessary for patients who have aneurysm sacs that are stable or shrinking at 1 year and no evidence of endoleak. To ex...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Tomlinson J,McNamara J,Matloubieh J,Hart J,Singh MJ,Davies MG,Rhodes JM,Illig KA

    更新日期:2007-11-01 00:00:00

  • Outcomes of Bypass Support Use during Inferior Vena Cava Resection and Reconstruction.

    abstract:BACKGROUND:The safety and effectiveness of using venovenous and cardiopulmonary bypass for resection of the inferior vena cava (IVC) is not well studied. The goal of this study was to compare outcomes following IVC resection with and without bypass support. METHODS:We analyzed all patients undergoing IVC resection at ...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Glebova NO,Hicks CW,Piazza KM,Lum YW,Abularrage CJ,Black JH 3rd

    更新日期:2016-01-01 00:00:00

  • Stent-Assisted Coil Embolization of a Symptomatic Renal Artery Aneurysm at a Bifurcation Point.

    abstract:BACKGROUND:Symptomatic renal artery aneurysms at bifurcation points present challenging clinical scenarios rarely amenable to endovascular repair due to concerns regarding parenchymal loss following intervention. Herein, we add to the scant body of literature describing successful endovascular repair of a saccular, sym...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Nassiri N,Huntress LA

    更新日期:2017-07-01 00:00:00

  • Popliteal vein thrombosis after radiofrequency ablation of greater saphenous vein for varicose vein.

    abstract::Percutaneous endovenous techniques, such as radiofrequency ablation (RFA), have become the preferred method for treatment for varicose veins associated with great saphenous vein (GSV) insufficiency. Reports have shown safety and efficacy of these techniques with relatively few complications. Deep venous thrombosis aft...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Tan TW,Chong TT,Marcaccio EJ Jr

    更新日期:2010-11-01 00:00:00

  • Amputation-free Survival in Patients with Critical Limb Ischemia Treated with Paclitaxel-eluting Stents and Paclitaxel-coated Balloons.

    abstract:OBJECTIVE:The aim of this study was to evaluate the performance of paclitaxel-eluting stents (PESs) and paclitaxel-coated balloons (PCBs) on amputation-free survival in patients with critical limb ischemia (CLI). METHODS:A retrospective review of all patients with Rutherford stage 5 and 6 limb ischemia undergoing endo...

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    authors: Phair J,Carnevale M,Lipsitz EC,Shariff S,Scher L,Garg K

    更新日期:2020-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Sullivan VV,Higgenbotham C,Shanley CJ,Fowler J,Lampman RM,Whitehouse WM Jr,Wolk SW

    更新日期:2003-05-01 00:00:00

  • In vitro effects of Nd:YAG laser radiation on blood: a quantitative and morphologic analysis.

    abstract::Use of the Neodymium: yttrium -aluminum -garnet (Nd:YAG) laser to recanalize stenosed arteries may require delivery of the beam through blood. To assess the degree of hemolysis and debris formation, 54 samples of citrated whole blood were exposed to Nd:YAG laser radiation of varying powers (10, 20 and 30 watts) and du...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Borrero E,Rosenthal D,Otis JB

    更新日期:1988-01-01 00:00:00

  • Interactions at the blood/material interface.

    abstract::The complex interactions occurring at the blood/material interface of implanted blood-contacting biomaterials largely determine the clinical efficacy of small diameter vascular grafts. Physical characteristics of the material such as chemical composition, electrical charge, surface texture, elastic modulus, and porosi...

    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Greisler HP

    更新日期:1990-01-01 00:00:00

  • Do not bite the hand that feeds you.

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    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Dryton G,Allen KB,Borkon AM,Aggarwal S,Davis JR

    更新日期:2015-02-01 00:00:00

  • Simulated Wound Assessment Using Digital Planimetry versus Three-Dimensional Cameras: Implications for Clinical Assessment.

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    journal_title:Annals of vascular surgery

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    authors: Williams KJ,Sounderajah V,Dharmarajah B,Thapar A,Davies AH

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    journal_title:Annals of vascular surgery

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    authors: Lehnert B,Wadouh F

    更新日期:1992-03-01 00:00:00

  • Posttraumatic lingual artery pseudoaneurysm treated with ultrasound-guided percutaneous thrombin injection.

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    pub_type: 杂志文章


    authors: Masella PC,Hanson MM,Hall BT,Verghese JJ,Kellicut DC

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  • Endovascular management of severe bleeding after major abdominal surgery.

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    authors: Boufi M,Hashemi AA,Azghari A,Hartung O,Ramis O,Moutardier V,Alimi YS

    更新日期:2013-11-01 00:00:00

  • Pancreaticoduodenal artery aneurysm associated with median arcuate ligament syndrome.

    abstract::Aneurysm of the pancreaticoduodenal artery arcade has a well-documented association with occlusion of the celiac axis. The etiology of celiac occlusion is most commonly atherosclerotic disease. Occlusion or severe stenosis of the celiac artery secondary to a median arcuate ligament is less frequently encountered, and ...

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    pub_type: 杂志文章,评审


    authors: Armstrong MB,Stadtlander KS,Grove MK

    更新日期:2014-04-01 00:00:00

  • Oxygen Delivery Therapy with EPIFLO Reduces Wound Hyperperfusion in Patients with Chronic Leg Ulcers: A Laser Speckle Contrast Analysis.

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    pub_type: 杂志文章


    authors: Varetto G,Verzini F,Trucco A,Frola E,Spalla F,Gibello L,Boero M,Capaldi G,Rispoli P

    更新日期:2020-04-01 00:00:00

  • Interfascial Plane Blocks Reduce Postoperative Pain and Morphine Consumption in Thoracic Outlet Decompression.

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    journal_title:Annals of vascular surgery

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  • Great saphenous vein stripping with liberal use of subfascial endoscopic perforator vein surgery (SEPS).

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    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Jeanneret C,Fischer R,Chandler JG,Galeazzi RL,Jäger KA

    更新日期:2003-09-01 00:00:00

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  • Spinal cord, bowel, and buttock ischemia after endovascular aneurysm repair.

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  • Ischemic colitis following translumbar thrombin injection for treatment of endoleak.

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    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Gambaro E,Abou-Zamzam AM Jr,Teruya TH,Bianchi C,Hopewell J,Ballard JL

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  • Balloon angioplasty induces heat shock protein 70 in human blood vessels.

    abstract::Balloon angioplasty produces a mechanically induced injury to the blood vessel wall. Heat shock protein 70 (HSP70) is a molecular chaperone whose expression can be induced by chemical or thermal stress. Thus, we hypothesized that the mechanical injury associated with balloon angioplasty would lead to increases in the ...

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  • A stroke/vascular neurology service increases the volume of urgent carotid endarterectomies performed in a tertiary referral center.

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  • Preservation of Stent Graft after Iatrogenic Type III Endoleak during Open Transperitoneal Surgical Intervention for Complicated Type II Endoleak.

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  • Endovascular Treatment of Juxtarenal Abdominal Aortic Aneurysms Recurring to the "Vent Technique".

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  • Evaluation of thrombogenicity of fluoropassivated polyester patches following carotid endarterectomy.

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Pedrini L,Dondi M,Magagnoli A,Magnoni F,Pisano E,Del Giudice E,Santoro M

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    journal_title:Annals of vascular surgery

    pub_type: 杂志文章


    authors: Greant P,Van den Brande P

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    pub_type: 杂志文章


    authors: Ichihashi S,Higashiura W,Itoh H,Tabayashi N,Sakaguchi S,Kichikawa K

    更新日期:2013-08-01 00:00:00

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    pub_type: 杂志文章


    authors: Radak D,Tanaskovic S,Vucurevic G,Aleksic N,Opric D,Ilijevski N

    更新日期:2010-08-01 00:00:00

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    pub_type: 杂志文章


    authors: Nekkanti M,Sivagnanam K,Bhat PS

    更新日期:2016-02-01 00:00:00

  • Repair of Delayed Type 1a Endoleak using Fenestrated and Parallel Endografts.

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    pub_type: 杂志文章


    authors: Reddy NP,Ham SW,Weaver FA,Rowe VL,Ziegler KR,Han SM

    更新日期:2018-05-01 00:00:00