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Poly-guanidinoethylphenylethers organised around a benzene ring: synthesis and evaluation of their antibacterial and cytotoxic properties.

Abstract：

:A new family of poly-guanidinium species with a benzene core as the organising agent has been developed. Their antibacterial properties have been evaluated against reference Gram positive and Gram negative bacteria, and their cytotoxicity against eukaryotic cells. Most of these compounds exhibited Minimum Inhibitory Concentrations in the micromolar range.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Massimba Dibama H,Mourer M,Duval RE,Regnouf-de-Vains JB

doi

10.1016/j.bmcl.2014.09.013

subject

Has Abstract

pub_date

2014-10-15 00:00:00

pages

4791-3

issue

20

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(14)00938-X

journal_volume

24

pub_type

杂志文章

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