The effects of fasting on 24-h gastric secretion of patients with duodenal ulcers resistant to ranitidine.

abstract：BACKGROUND:Non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious gastrointestinal side effects. Faecal calprotectin assay represents a simple and practical method for diagnosis of NSAID enteropathy. Intestinal micro-organisms are necessary for the development of NSAID-induced small bowel lesions and hence it...

journal_title：Alimentary pharmacology & therapeutics

authors： Montalto M,Gallo A,Curigliano V,D'Onofrio F,Santoro L,Covino M,Dalvai S,Gasbarrini A,Gasbarrini G

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Recently, a rapid-release 100-mg 13C-urea tablet with citrate supplement (Diabact UBT) showed excellent performance in a European population. AIM:To investigate the accuracy of a 50-mg tablet-based 13C-urea breath test protocol. METHODS:: Consecutive dyspeptic patients referred for upper endoscopy were rec...

journal_title：Alimentary pharmacology & therapeutics

authors： Wong WM,Lam SK,Lai KC,Chu KM,Xia HH,Wong KW,Cheung KL,Lin SK,Wong BC

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Pancreatic enzyme replacement therapy (PERT) is necessary to prevent severe maldigestion and unwanted weight loss associated with exocrine pancreatic insufficiency (EPI) due to chronic pancreatitis (CP) or pancreatic surgery (PS). AIM:To assess the long-term safety and efficacy of pancrelipase (pancreatin) ...

journal_title：Alimentary pharmacology & therapeutics

authors： Gubergrits N,Malecka-Panas E,Lehman GA,Vasileva G,Shen Y,Sander-Struckmeier S,Caras S,Whitcomb DC

更新日期：2011-05-01 00:00:00

abstract：AIM:To study the effect of prokinetic treatment with cisapride in patients with constipation-predominant irritable bowel syndrome. PATIENTS AND METHODS:Ninety-six patients were randomly assigned to treatment with either cisapride 5 mg three times daily or placebo three times daily for a period of 12 weeks. The dosage ...

journal_title：Alimentary pharmacology & therapeutics

authors： Schütze K,Brandstätter G,Dragosics B,Judmaier G,Hentschel E

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Two variants in the organic cation transporter gene cluster have been recently reported to confer susceptibility to Crohn's disease (CD). AIM:To investigate these variants in CD and ulcerative colitis (UC), and their interaction with CARD15 gene and correlation to clinical subphenotypes. METHODS:Case-contr...

journal_title：Alimentary pharmacology & therapeutics

authors： Palmieri O,Latiano A,Valvano R,D'Incà R,Vecchi M,Sturniolo GC,Saibeni S,Peyvandi F,Bossa F,Zagaria C,Andriulli A,Devoto M,Annese V

更新日期：2006-02-15 00:00:00

abstract：BACKGROUND:Bodybuilding supplements can cause a profound cholestatic syndrome. AIM:To describe the drug-Induced liver injury network's experience with liver injury due to bodybuilding supplements. METHODS:Liver injury pattern, severity and outcomes, potential genetic associations, and exposure to anabolic steroids by...

journal_title：Alimentary pharmacology & therapeutics

authors： Stolz A,Navarro V,Hayashi PH,Fontana RJ,Barnhart HX,Gu J,Chalasani NP,Vega MM,Bonkovsky HL,Seeff LB,Serrano J,Avula B,Khan IA,Cirulli ET,Kleiner DE,Hoofnagle JH,DILIN Investigators.

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:It is not clear which dose of clarithromycin (500 mg b.d. or 250 mg b.d.) is more effective for Helicobacter pylori eradication in proton pump inhibitor-based triple therapies. METHODS:We undertook a meta-analysis of the effect of 7-day triple therapies consisting of a proton pump inhibitor (P), and clarith...

journal_title：Alimentary pharmacology & therapeutics

authors： Huang J,Hunt RH

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) genotype 6 is common among patients from Southeast Asia and the surrounding regions, where HCV prevalence is also high. HCV genotype 6 has great genetic diversity and different response to antiviral therapy compared with the more commonly known genotype 1. AIM:Our goal was to provide...

journal_title：Alimentary pharmacology & therapeutics

authors： Chao DT,Abe K,Nguyen MH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Pantoprazole is a new substituted benzimidazole that blocks the H+/K(+)-ATPase in the gastric mucosa and thus inhibits acid secretion. METHODS:Efficacy and tolerability of pantoprazole (40 mg at breakfast) and ranitidine (300 mg at bedtime) in the treatment of uncomplicated acute duodenal ulcer were compare...

journal_title：Alimentary pharmacology & therapeutics

authors： Judmaier G,Koelz HR

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Epidemiological studies of microscopic colitis have shown varying but increasing incidence rates. AIM:To assess the incidence of microscopic colitis in Sweden. METHODS:Nationwide cohort study performed in 1995-2015 based on biopsy reports. Age-specific and age-standardised incidence rates were calculated. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Bergman D,Clements MS,Khalili H,Agréus L,Hultcrantz R,Ludvigsson JF

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Symptoms of lactose intolerance are often attributed to lactose malabsorption but, as this relationship has not been demonstrated when a small dose of lactose similar to that contained in one cup of milk is ingested by intolerant patients, psychological factors may play a role in altered symptom perception. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Tomba C,Baldassarri A,Coletta M,Cesana BM,Basilisco G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Currently, the relationship between depression and non-alcoholic fatty liver disease (NAFLD) is not clearly defined. AIM:To determine whether depression is associated with NAFLD and NAFLD-related advanced fibrosis in a large population sample. METHODS:We performed a cross-sectional analysis using the 2007-...

journal_title：Alimentary pharmacology & therapeutics

authors： Kim D,Yoo ER,Li AA,Tighe SP,Cholankeril G,Harrison SA,Ahmed A

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:There are limited data concerning infliximab drug monitoring during de-escalation of the treatment of inflammatory bowel disease (IBD). AIM:To define the rate and the predictors of relapse following infliximab de-escalation in IBD patients in remission. METHODS:All IBD patients at a single referral centre ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lucidarme C,Petitcollin A,Brochard C,Siproudhis L,Dewitte M,Landemaine A,Bellissant E,Bouguen G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Butyrate, propionate and acetate are short chain fatty acids (SCFA), important for maintaining a healthy colon and are considered as protective in colorectal carcinogenesis. However, they may also regulate immune responses and the composition of the intestinal microbiota. Consequently, their importance in a ...

journal_title：Alimentary pharmacology & therapeutics

authors： Gill PA,van Zelm MC,Muir JG,Gibson PR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:In vitro studies suggest interactions between mesalazine (mesalamine) and thiopurines by thiopurine S-methyltransferase (TPMT) inhibition, influencing the balance of hepatotoxic 6-methylmercaptopurine ribonucleotide and immunosuppressive tioguanine (thioguanine) metabolites. AIM:To examine the in vivo pharm...

journal_title：Alimentary pharmacology & therapeutics

authors： Gilissen LP,Bierau J,Derijks LJ,Bos LP,Hooymans PM,van Gennip A,Stockbrügger RW,Engels LG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome is a widespread disorder with a marked socioeconomic burden. Previous studies support the proposal that a subset of patients with features compatible with diarrhoea-predominant IBS (IBS-D) have bile acid malabsorption (BAM). AIM:To perform a systematic review and meta-analysis to as...

journal_title：Alimentary pharmacology & therapeutics

authors： Slattery SA,Niaz O,Aziz Q,Ford AC,Farmer AD

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Hepatitis vaccination is recommended in patients with chronic liver disease. AIM:To validate Current Procedural Terminology (CPT) codes and drug codes for hepatitis vaccination in administrative databases and determine vaccination rates in hepatitis C virus (HCV)-infected patients in a single large Veterans...

journal_title：Alimentary pharmacology & therapeutics

authors： Hachem CY,Kramer JR,Kanwal F,El-Serag HB

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:No validated patient-reported outcome (PRO) measure exists for functional dyspepsia (FD) assessment. Verbal descriptions of different upper abdominal symptoms may be poorly distinguishable to patients. AIM:To investigate whether understanding of FD symptoms is enhanced by pictograms symbolising the nature o...

journal_title：Alimentary pharmacology & therapeutics

authors： Tack J,Carbone F,Holvoet L,Vanheel H,Vanuytsel T,Vandenberghe A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Omeprazole has become available in a tablet formulation, a Multiple Unit Pellet System (MUPS) containing a large number of small individually enteric-coated micropellets. AIM:To compare the acid-inhibitory effect of omeprazole MUPS 20 mg with pantoprazole 40 mg and to describe the pharmacokinetics of both d...

journal_title：Alimentary pharmacology & therapeutics

authors： Geus WP,Mathôt RA,Mulder PG,Lamers CB

更新日期：2000-08-01 00:00:00

abstract：:Bismuth preparations are commonly used to treat a variety of gastrointestinal disorders, including peptic ulcers and dyspepsia. The safety profile of currently approved bismuth preparations, such as tripotassium dicitrato bismuthate (De-Nol), bismuth subsalicylate (Pepto-Bismol) and ranitidine bismuth citrate (Pylorid...

journal_title：Alimentary pharmacology & therapeutics

authors： Tillman LA,Drake FM,Dixon JS,Wood JR

更新日期：1996-08-01 00:00:00

abstract：:Faecal impaction with or without encopresis is a very common problem. We performed a randomized, open-label, prospective study to compare the efficacy and acceptability of the treatment of faecal impaction using either mineral oil or pineapple-flavoured isotonic intestinal lavage solution containing polyethylene glyco...

journal_title：Alimentary pharmacology & therapeutics

authors： Tolia V,Lin CH,Elitsur Y

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors are effective for the healing of oesophagitis. Standard doses of omeprazole, lansoprazole or pantoprazole are sufficient for healing in mild to moderate cases of oesophagitis. AIM:To compare the efficacy of double the standard doses of omeprazole, lansoprazole or pantoprazole for main...

journal_title：Alimentary pharmacology & therapeutics

authors： Jaspersen D,Diehl KL,Schoeppner H,Geyer P,Martens E

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Imbalance between apoptosis and proliferation may be one of the mechanisms underlying H. pylori associated gastric carcinogenesis. AIM:To examine the cell kinetics of gastric intestinal metaplasia and the effect of H. pylori eradication. METHODS:Endoscopic gastric biopsies were obtained from 100 H. pylori-...

journal_title：Alimentary pharmacology & therapeutics

authors： Leung WK,Yu J,To KF,Go MY,Ma PK,Chan FK,Sung JJ

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The seroclearance of hepatitis B surface antigen (HBsAg) in patients with chronic hepatitis B (CHB) is considered to be associated with favourable clinical outcomes. AIMS:This meta-analysis was performed to establish the proportion of HBsAg loss rates among CHB patients who received combination treatment ba...

journal_title：Alimentary pharmacology & therapeutics

authors： Qiu K,Liu B,Li SY,Li H,Chen ZW,Luo AR,Peng ML,Ren H,Hu P

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:In the past decade, a number of population-based studies have examined the prevalence of coeliac disease in individuals with type 1 diabetes but prevalences have differed considerably. AIM:To examine the prevalence of coeliac disease in individuals with type 1 diabetes. METHODS:A systematic review of Engli...

journal_title：Alimentary pharmacology & therapeutics

authors： Elfström P,Sundström J,Ludvigsson JF

更新日期：2014-11-01 00:00:00

abstract：:Although up to 50% of patients diagnosed with nonulcer dyspepsia (NUD) have Helicobacter pylori infection and underlying chronic gastritis, it remains controversial whether any causal relationship exists. The results of worldwide epidemiological studies have been unconvincing. No clear-cut link has been documented bet...

journal_title：Alimentary pharmacology & therapeutics

authors： Talley NJ,Quan C

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The efficacy of cyclosporin in the management of ulcerative colitis is recognized. Not all patients respond to this treatment. Existing clinical and laboratory parameters are of little use in identifying those most likely to respond. AIMS:To determine whether in-vitro sensitivity to cyclosporin as measured ...

journal_title：Alimentary pharmacology & therapeutics

authors： McCormack G,O'Donoghue D,Baird A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:In patients with idiopathic non-cirrhotic portal hypertension (INCPH), the usual recommended strategy for management of variceal bleeding is the same as that in cirrhosis. However, this policy has been challenged by the different natural history between INCPH and cirrhosis. AIM:To compare outcomes after tra...

journal_title：Alimentary pharmacology & therapeutics

authors： Lv Y,Li K,He C,Luo B,Zhang B,Liu H,Wang Z,Guo W,Wang Q,Chen H,Bai W,Yuan X,Yu T,Li X,Yuan J,Han N,Zhu Y,Niu J,Xie H,Wang J,Chen L,Yin Z,Fan D,Li Z,Han G

更新日期：2019-04-01 00:00:00

abstract：:Epidemiological, experimental, and clinical studies have demonstrated that colon carcinogenesis may be prevented by nonsteroidal anti-inflammatory drugs (NSAIDs). Although controversy remains, recent studies, including ours, have revealed that NSAIDs suppress colon carcinogenesis at the adenoma stage where cyclooxygen...

journal_title：Alimentary pharmacology & therapeutics

authors： Ota S,Bamba H,Kato A,Kawamoto C,Yoshida Y,Fujiwara K

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome is the most common diagnosis in gastroenterology. Trials suggest certain probiotics to be beneficial. AIM:To investigate the effects of multispecies probiotic supplementation (Lactobacillus rhamnosus GG, L. rhamnosus Lc705, Propionibacterium freudenreichii ssp. shermanii JS and Bifi...

journal_title：Alimentary pharmacology & therapeutics

authors： Kajander K,Myllyluoma E,Rajilić-Stojanović M,Kyrönpalo S,Rasmussen M,Järvenpää S,Zoetendal EG,de Vos WM,Vapaatalo H,Korpela R

更新日期：2008-01-01 00:00:00