Abstract:
:To determine whether serum beta 2 microglobulin could be useful as a tumor marker in patients with testicular cancers, sera stored in our serum bank from 23 patients were assayed by radioimmunoassay for beta 2 microglobulin levels. Sera were selected from 12 preorchiectomy patients, 8 patients who had undergone orchiectomy, and 3 patients who had undergone orchiectomy and retroperitoneal lymphadenectomy. Patients with other genitourinary tract disorders and normal age and sex-matched controls were assayed for comparison. The laboratory range for normal serum beta 2 microglobulin values was 1.1 to 2.4 mg/L. Patients without documented testicular tumors had values ranging from 1.4 to 9.7 mg/L. Values for normal controls ranged from 1.7 to 2.4 mg/L. Only 3 patients (12.5 per cent) had elevated serum beta 2 microglobulin values. Serum beta 2 microglobulin seems to have no value as a tumor marker in patients with testicular tumors.
journal_name
Urologyjournal_title
Urologyauthors
Johnson H Jr,Flye MW,Javadpour Ndoi
10.1016/0090-4295(80)90614-7subject
Has Abstractpub_date
1980-11-01 00:00:00pages
522-4issue
5eissn
0090-4295issn
1527-9995pii
0090-4295(80)90614-7journal_volume
16pub_type
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