Abstract：
OBJECTIVES:To determine the incidence of urinary incontinence in men with prostate cancer treated with definitive external-beam radiation therapy and to analyze the impact of various patient and treatment variables on the development of urinary incontinence. METHODS:The records of all 758 men who received definitive external-beam radiation therapy at our institution between October 1986 and December 1994 were reviewed. The development of incontinence was recorded and graded according to the Late Effects Normal Tissues/Radiation Therapy Oncology Group (LENT/RTOG) scoring system. RESULTS:Late grade 2 or higher urinary incontinence developed in 4 of 758 patients (0.5%) (3 grade 2; 1 grade 3). The actuarial urinary incontinence rate was 1.3% at 5 years. Patients with a history of prior transurethral resection of the prostate (TURP) had higher rates of urinary incontinence than patients without prior TURP (prior TURP 3 of 132 [2%] versus 1 of 626 [0.2%]; P = 0.02). CONCLUSIONS:Urinary incontinence following definitive external-beam radiation therapy for clinically localized prostate cancer is a rare event. Previous TURP increases the risk of incontinence, although the risk remains low. There is no evidence that higher doses to the prostate using conformal techniques are associated with an increased risk of urinary incontinence.
journal_name
Urologyjournal_title
Urologyauthors
Lee WR,Schultheiss TE,Hanlon AL,Hanks GEdoi
10.1016/s0090-4295(96)00085-4subject
Has Abstractpub_date
1996-07-01 00:00:00pages
95-9issue
1eissn
0090-4295issn
1527-9995pii
S0090-4295(96)00085-4journal_volume
48pub_type
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