Acceleration of capsule formation around silicone implants by infection in a guinea pig model.

Abstract:

:Fibrous capsules surrounding silicone implants were investigated in a new guinea pig model to delineate some of the factors leading to capsular contracture. Both the implant surfaces and tissue capsules were examined by light and scanning transmission electron microscopy (STEM + SEM) with x-ray energy spectroscopy (XES). The capsular tissues were qualitatively similar to those recovered clinically, showing dense parallel collagen deposits, fibroblasts, myofibroblasts, macrophages, and foreign-body giant cells. Silicone was positively identified within intercellular vacuoles and the rough endoplasmic reticulum of macrophages by XES. Tissue recovered from the capsules that surrounded implants that were contaminated with S. aureus presented a qualitatively similar histologic spectrum. The contaminated specimens did show an accelerated response. SEM showed a cellular invasion of the silicone envelopes. We conclude that the model accurately simulates the clinical situation and suggests that immune mechanisms may play a key role in capsular contracture.

journal_name

Plast Reconstr Surg

authors

Kossovsky N,Heggers JP,Parsons RW,Robson MC

doi

10.1097/00006534-198401000-00021

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

91-8

issue

1

eissn

0032-1052

issn

1529-4242

journal_volume

73

pub_type

杂志文章
  • Comparison of local recurrence and distant metastases between breast cancer patients after postmastectomy radiotherapy with and without immediate TRAM flap reconstruction.

    abstract:BACKGROUND:The purpose of this study was to compare the local recurrence and distant metastasis of postmastectomy radiotherapy for breast cancer patients with and without immediate transverse rectus abdominis musculocutaneous (TRAM) flap reconstruction. METHODS:Between March of 1997 and October of 2001, 191 breast can...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000220527.35442.44

    authors: Huang CJ,Hou MF,Lin SD,Chuang HY,Huang MY,Fu OY,Lian SL

    更新日期:2006-10-01 00:00:00

  • Method for intraoperative positioning of the nipple-areola complex in vertical scar reduction mammaplasty.

    abstract::The desired shape and position of the nipple-areola complex may be difficult to achieve in vertical scar reduction mammaplasty when using the standard technique of preoperative marking of the so-called mosque-shaped areolar pattern of excision. We describe our modified approach of intraoperative final positioning of t...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200005000-00028

    authors: Vogt PM,Mühlberger T,Torres A,Peter FW,Steinau HU

    更新日期:2000-05-01 00:00:00

  • Combined anterolateral thigh flap and vascularized fibula osteoseptocutaneous flap in reconstruction of extensive composite mandibular defects.

    abstract::Extensive composite defects of the oromandibular area are usually created after the surgical treatment of T3 and T4 cancers, requiring complex reconstructive plastic surgical procedures. The preferred treatment method for this type of defect is reconstruction with two free flaps. The use of the vascularized fibula ost...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200201000-00008

    authors: Wei FC,Celik N,Chen HC,Cheng MH,Huang WC

    更新日期:2002-01-01 00:00:00

  • Trigonocephaly-associated hypotelorism: is treatment necessary?

    abstract::This study was designed to examine whether hypotelorism associated with trigonocephaly might be self-correcting. Only patients who required surgical treatment and had undergone preoperative and postoperative anthropometric measurements were included. In no case was any attempt made to correct the hypotelorism surgical...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199603000-00001

    authors: Fearon JA,Kolar JC,Munro IR

    更新日期:1996-03-01 00:00:00

  • Comparison of Outcomes following Autologous Breast Reconstruction Using the DIEP and Pedicled TRAM Flaps: A 12-Year Clinical Retrospective Study and Literature Review.

    abstract:BACKGROUND:There are few studies that compare the deep inferior epigastric artery perforator (DIEP) flap to the pedicled transverse rectus abdominis myocutaneous (pTRAM) flap for use in reconstructive breast surgery. The authors examined four factors that aid in decision-making: donor-site morbidity, need for surgery r...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/PRS.0000000000001747

    authors: Knox ADC,Ho AL,Leung L,Tashakkor AY,Lennox PA,Van Laeken N,Macadam SA

    更新日期:2016-07-01 00:00:00

  • Nasolabial rotation flaps based on the upper lateral lip subunit for superficial and large defects of the upper lateral lip.

    abstract:BACKGROUND:Reconstruction of the defects of the upper lateral lip is still one of the most difficult challenges for plastic surgeons. No method specific to the superficial and larger defects of the upper lateral lip has been proposed before. Nasolabial rotation flaps based on the upper lateral lip subunit for superfici...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e31825dc09f

    authors: Burget GC,Hsiao YC

    更新日期:2012-09-01 00:00:00

  • Randomized comparison of the single-injection volar subcutaneous block and the two-injection dorsal block for digital anesthesia.

    abstract:BACKGROUND:Two commonly used methods of digital nerve block with local anesthetic are the two-injection dorsal technique and the single-injection volar subcutaneous technique. The authors compared these two digital block techniques with respect to local anesthetic injection pain and recipient preference of anesthetic t...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.prs.0000237016.00941.96

    authors: Williams JG,Lalonde DH

    更新日期:2006-10-01 00:00:00

  • Extended transverse rectus abdominis musculocutaneous flap.

    abstract::The transverse rectus abdominis musculocutaneous flap is widely used for breast reconstruction, but it does not have a rich blood supply. A previous article described the inclusion of superficial epigastric vessels and superficial circumflex iliac vessels to "supercharge" the flap. Subsequent experience has shown that...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199309001-00033

    authors: Takayanagi S

    更新日期:1993-09-01 00:00:00

  • Classifying deformities of the columella base in rhinoplasty.

    abstract:BACKGROUND:Although much has been published with regard to the columella assessed on the frontal and lateral views, a paucity of literature exists regarding the basal view of the columella. The objective of this study was to evaluate the spectrum of columella deformities and devise a working classification system based...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000000022

    authors: Lee MR,Tabbal G,Kurkjian TJ,Roostaeian J,Rohrich RJ

    更新日期:2014-04-01 00:00:00

  • A prospective, randomized surveillance study of postoperative wound infections after plastic surgery: a study of incidence and surveillance methods.

    abstract::In a postoperative wound infection study in plastic surgery, 315 patients were randomized to either outpatient wound control after 30 days (group I) or self-control by questionnaire (group II). We present a new definition of wound infection based on physiologic wound healing. The surveillance of postoperative wound in...

    journal_title:Plastic and reconstructive surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006534-199509001-00028

    authors: Andenaes K,Amland PF,Lingaas E,Abyholm F,Samdal F,Giercksky KE

    更新日期:1995-09-01 00:00:00

  • Accompanying arteries of the lesser saphenous vein and sural nerve: anatomic study and its clinical applications.

    abstract::The arteries adjacent to the lesser saphenous vein and sural nerve were investigated in 10 fresh cadavers that had been systemically injected with a lead oxide-gelatin mixture. The accompanying arteries were found to lie along the lesser saphenous vein and sural nerve and to nourish the skin through venocutaneous and ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199901000-00018

    authors: Nakajima H,Imanishi N,Fukuzumi S,Minabe T,Fukui Y,Miyasaka T,Kodama T,Aiso S,Fujino T

    更新日期:1999-01-01 00:00:00

  • A new, fast surgical knot for skin closures.

    abstract::A modified surgeon's knot is proposed. Tying is based on twisting the throws instead of laying them down flat. The second (granny) throw is snugged against the first in a locking manner. The knot is tied rapidly by needleholder and is particularly useful for skin sutures with monofilament thread. ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198503000-00026

    authors: Meiss L

    更新日期:1985-03-01 00:00:00

  • Incidence of cervical branch injury with "marginal mandibular nerve pseudo-paralysis" in patients undergoing face lift.

    abstract::The anatomy of the cervical and marginal mandibular branches of the facial nerve is reviewed. In the senior author's practice, "pseudoparalysis of the marginal mandibular nerve" due to cervical branch injury occurred in 34 of 2002 superficial musculoaponeurotic system-platysma face lifts (1.7 percent) and was associat...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.PRS.0000061004.74788.33

    authors: Daane SP,Owsley JQ

    更新日期:2003-06-01 00:00:00

  • APACHE II scoring for the prediction of immediate surgical complications in head and neck cancer patients.

    abstract:BACKGROUND:Aggressive surgical treatment of oral and oropharyngeal cancers may be compromised by significant surgical complications. Early identification of patients at risk for postoperative complications may assist in clinical decision-making. The objective of this study was to assess the value of the Acute Physiolog...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000259038.36210.f8

    authors: Grant CA,Dempsey GA,Lowe D,Brown JS,Vaughan ED,Rogers SN

    更新日期:2007-05-01 00:00:00

  • Are Quantitative Measures of Academic Productivity Correlated with Academic Rank in Plastic Surgery? A National Study.

    abstract:BACKGROUND:The purpose of this study was to investigate the correlation between quantitative measures of academic productivity and academic rank among full-time academic plastic surgeons. METHODS:Bibliometric indices were computed for all full-time academic plastic surgeons in the United States. The primary study vari...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000001531

    authors: Susarla SM,Lopez J,Swanson EW,Miller D,O'Brien-Coon D,Zins JE,Serletti JM,Yaremchuk MJ,Manson PN,Gordon CR

    更新日期:2015-09-01 00:00:00

  • Breast reconstruction with the latissimus dorsi flap: women's preference for scar location.

    abstract:BACKGROUND:Refinements made in latissimus dorsi breast reconstruction have improved the aesthetic appearance of the breast without changing the donor-site location. The optimal location for donor-site placement, from a patient's perspective, is still unknown. The purpose of this study was to assess women's preference f...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e3181de1b41

    authors: Bailey S,Saint-Cyr M,Zhang K,Mojallal A,Wong C,Ouyang D,Maia M,Zhang S,Rohrich RJ

    更新日期:2010-08-01 00:00:00

  • Defining fat necrosis in plastic surgery.

    abstract:BACKGROUND:Fat necrosis is a well-known complication of free tissue transfer and fat grafting that is becoming increasingly reported in the literature. However, there is no clear consensus on how fat necrosis is defined and classified in the plastic surgery literature. METHODS:A systematic review of the literature was...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/PRS.0000000000000700

    authors: Rao A,Saadeh PB

    更新日期:2014-12-01 00:00:00

  • Ultrasound diagnosis of cleft lip and cleft palate before birth.

    abstract::Real-time ultrasonography in pregnancy can accurately detect gestational age, position of the fetus, position of the placenta, sex of the fetus, and many congenital anomalies before birth. To date, however, there has been no report of detection of a cleft lip-palate deformity by ultrasound. Two cases, in approximately...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198112000-00002

    authors: Christ JE,Meininger MG

    更新日期:1981-12-01 00:00:00

  • Telescoping and glue technique in vein grafts for arterial defects.

    abstract::Fibrin glue was applied at the anastomotic site of the vein graft that was placed in rat femoral artery defects by the telescoping anastomotic technique at both proximal and distal anastomoses. All 35 vein grafts thus placed were patent, yielding a statistically higher patency rate than those placed in the same femora...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199511000-00026

    authors: Saitoh S,Nakatsuchi Y

    更新日期:1995-11-01 00:00:00

  • Recurrent ventral herniation in Ehlers-Danlos syndrome.

    abstract::Ehlers-Danlos syndrome is an inherited collagen disorder characterized by skin hyperextensibility, joint laxity, and tissue friability. In this study, it was hypothesized that Ehlers-Danlos syndrome is frequently undiagnosed in patients who present for repair of ventral abdominal wall hernias. A retrospective chart re...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-200012000-00012

    authors: Girotto JA,Malaisrie SC,Bulkely G,Manson PN

    更新日期:2000-12-01 00:00:00

  • Treatment of breast animation deformity in implant-based reconstruction with pocket change to the subcutaneous position.

    abstract:UNLABELLED:Breast animation may be an unfortunate result of subpectoral implant-based reconstruction following mastectomy. This article reviews a novel approach to the treatment of animation deformity in cases of reconstruction, whereby the pectoralis major muscle is sutured down to the chest wall and the implant is tr...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000001277

    authors: Hammond DC,Schmitt WP,O'Connor EA

    更新日期:2015-06-01 00:00:00

  • The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture.

    abstract:BACKGROUND:Capsular contracture remains a major problem following prosthetic breast implantation, especially in patients undergoing irradiation. Recent studies suggest that such radiation injuries are a cascading process of cytokine activation, with transforming growth factor (TGF)-β acting as the "master switch." Beca...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e3182131bea

    authors: Katzel EB,Koltz PF,Tierney R,Williams JP,Awad HA,O'Keefe RJ,Langstein HN

    更新日期:2011-06-01 00:00:00

  • Comparison of Allergan, Mentor, and Sientra Contoured Cohesive Gel Breast Implants: A Single Surgeon's 10-Year Experience.

    abstract:BACKGROUND:Contoured cohesive gel breast implants have been recently approved in the United States. These implants have been available for premarket approval studies for selected surgeons. The purpose of this study was to assess a single surgeon's outcomes in three specific clinical situations-breast augmentation, seco...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000001675

    authors: Doren EL,Pierpont YN,Shivers SC,Berger LH

    更新日期:2015-11-01 00:00:00

  • The dual role of perichondrium in cartilage wound healing.

    abstract::Cartilage structures from the head and neck possess a certain but limited capacity to heal after injury. This capacity is accredited to the perichondrium. In this study, the role of the inner (cambium) and the outer (fibrous) layers of the perichondrium in cartilage wound healing in vitro is investigated. For the firs...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.PRS.0000020991.10201.6C

    authors: Duynstee ML,Verwoerd-Verhoef HL,Verwoerd CD,Van Osch GJ

    更新日期:2002-09-15 00:00:00

  • Lessons from American Board of Plastic Surgery Maintenance of Certification Tracer Data: A 16-Year Review of Clinical Practice Patterns and Evidence-Based Medicine in Cleft Palate Repair.

    abstract:BACKGROUND:As a component of the Maintenance of Certification process from 2003 to 2019, the American Board of Plastic Surgery tracked 20 common plastic surgery operations. By evaluating the data collected over 16 years, the authors are able to examine the practice patterns of pediatric/craniofacial surgeons in the Uni...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000007018

    authors: Kearney AM,Gart MS,Brandt KE,Gosain AK

    更新日期:2020-08-01 00:00:00

  • Teaching plastic surgeons how to be better teachers.

    abstract::The purpose of this article is to introduce plastic surgeons to a theory of adult education. Most surgeons have been hired by their parent institution because of their clinical skills, and rightly so. At the same time, these same surgeons choose or are expected to be involved to varying degrees in the surgical educati...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e318252f19d

    authors: Weber RA,Armstrong EG

    更新日期:2012-05-01 00:00:00

  • On the origins of components separation.

    abstract:SUMMARY:The method of abdominal hernia repair known as components separation, described by Ramirez et al. in 1990, has enjoyed widespread popularity because of the sound anatomical principles it uses and most importantly the clinical success of the procedure. Although the authors who described this technique made no pr...

    journal_title:Plastic and reconstructive surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/PRS.0b013e3181b98ab8

    authors: Halvorson EG

    更新日期:2009-11-01 00:00:00

  • Improving reemployment rates after limb salvage of acute severe tibial fractures by microvascular soft-tissue reconstruction.

    abstract::Patients with severe open tibial fractures may have a low rate of reemployment after reconstruction. Sixty-five limb-salvage patients were followed for at least 2 years to determine the factors that influence future employment. The preinjury conditions found to influence reemployment included age less than 40, higher ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199404001-00019

    authors: Francel TJ

    更新日期:1994-04-01 00:00:00

  • Surgical correction of the inverted nipple with a tendon graft: hammock procedure.

    abstract::Our procedure, in which the inverted nipple was suspended using autogenous tendon grafts, was easy to perform, and it was not necessary to cut the lactiferous ducts. There was no deformity of the nipple or areola after this procedure, and the surgical scars were inconspicuous. Three patients who were followed up for o...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199011000-00030

    authors: Kurihara K,Maezawa N,Yanagawa H,Imai T

    更新日期:1990-11-01 00:00:00

  • Living Donation of Vascularized Composite Allografts.

    abstract::Living donation has become a medically and ethically accepted practice in solid organ transplantation. Published proceedings from the international kidney transplant community and from the Ethics Committee of The Transplantation Society articulated the general principles and specific recommendations for living donatio...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000004659

    authors: Pomahac B,Alhefzi M,Bueno EM,McDiarmid SV,Levin LS

    更新日期:2018-09-01 00:00:00