Living Donation of Vascularized Composite Allografts.

Abstract:

:Living donation has become a medically and ethically accepted practice in solid organ transplantation. Published proceedings from the international kidney transplant community and from the Ethics Committee of The Transplantation Society articulated the general principles and specific recommendations for living donation, which remain the backbone of Centers for Medicare and Medicaid Services and Organ Procurement and Transplantation Network requirements and policies. Meanwhile, there have been major advancements in another revolutionary field of transplant medicine: vascularized composite allotransplantation. Recent interventions have demonstrated potential for superior functional and aesthetic outcomes in a single operation when compared to staged conventional reconstructions. In view of these successes, the indications for vascularized composite allotransplantation are expected to broaden to include less extensive types of transplants, which would introduce the possibility of using living vascularized composite allotransplantation donors. In this article, the authors discuss the feasibility and ethics associated with living donation of vascularized composite allografts. The authors explore the current guidelines and policies set by the Organ Procurement and Transplantation Network regarding living organ donation. In addition, the authors provide several clinical scenarios in which living donation of vascularized composite allotransplantation could be used to augment the reconstructive ladder currently used by reconstructive surgeons to guide their reconstructive strategies.

journal_name

Plast Reconstr Surg

authors

Pomahac B,Alhefzi M,Bueno EM,McDiarmid SV,Levin LS

doi

10.1097/PRS.0000000000004659

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

405e-411e

issue

3

eissn

0032-1052

issn

1529-4242

pii

00006534-201809000-00053

journal_volume

142

pub_type

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