Neurocutaneous melanosis with extensive intracerebral and spinal cord involvement. Report of two cases.

Abstract:

:Two unusual cases of neurocutaneous melanosis are presented. Both patients had congenital giant hairy nevi and both developed hydrocephalus, seizures, and myelopathy. The first patient displayed multicentric cerebral and spinal cord melanosis, as opposed to the more commonly described basilar leptomeningeal involvement. The second patient had total spinal leptomeningeal involvement, and ventriculoperitoneal shunting for hydrocephalus produced peritoneal metastasis of melanoma. An individual born with a congenital giant hairy nevus or marked generalized cutaneous pigmentation should be closely observed for the development of malignant melanoma of the nervous system.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Faillace WJ,Okawara SH,McDonald JV

doi

10.3171/jns.1984.61.4.0782

subject

Has Abstract

pub_date

1984-10-01 00:00:00

pages

782-5

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

61

pub_type

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